Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Margo Peyton"'
Publikováno v:
Sunday, April 23.
Autor:
Charbel Moussa, Margo Peyton, Irina Lonskaya, Ruochong Wang, Xiaokong Gao, Xiaoguang Liu, Michaeline Hebron
Publikováno v:
Journal of Neuroimmunology. 311:1-9
The role of cell surface tyrosine kinase collagen-activated receptors known as discoidin domain receptors (DDRs) is unknown in neurodegenerative diseases. We detect up-regulation in DDRs level in post-mortem Alzheimer and Parkinson brains. Lentiviral
Autor:
Margo Peyton, Jaeil Ahn, Xiaoguang Liu, Alan J. Fowler, Michaeline Hebron, Sara Matar, Joy Arellano, Nadia Yusuf, Barbara Wilmarth, Charbel Moussa, Sorell L. Schwartz, Nathan J. Starr, Helen H. Howard, Fernando Pagan, Yasar Torres-Yaghi, Elizabeth E. Mundel, Abigail Lawler
Publikováno v:
Pharmacology Research & Perspectives
Nilotinib is a broad‐based tyrosine kinase inhibitor with the highest affinity to inhibit Abelson (c‐Abl) and discoidin domain receptors (DDR1/2). Preclinical evidence indicates that Nilotinib reduces the level of brain alpha‐synuclein and atte