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SGN-CD48A: a Novel Humanized Anti-CD48 Antibody-Drug Conjugate for the Treatment of Multiple Myeloma
Autor:
Chris Leiske, Che-Leung Law, Marsha Quick, Sa Wang, Maitrayee Goswami, Lori Westendorf, Devra Olson, Kristine A. Gordon, Margo Finn, Albina Nesterova, Sharsti Sandall, Germein Linares, Lanshan Huang, Timothy S. Lewis
Publikováno v:
Blood. 128:4470-4470
Multiple myeloma (MM) is an incurable hematologic malignancy of transformed plasma cells. New targeted biological therapeutics are needed to increase the stringency and durability of remissions. In this study we describe SGN-CD48A, a potent CD48-targ