Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Margit Szikszay"'
Autor:
Margit Szikszay, Géza Tóth, Sándor Benyhe, Fanni Tóth, Anna Borsodi, Judit Farkas, Gyongyi Horvath
Publikováno v:
Regulatory Peptides. 122:139-146
Tyr-D-Ala-Gly-Phe-D-Nle-Arg-Phe (DADN) a synthetic analogue of the endogenous Met-enkephalin-Arg-Phe (Tyr-Gly-Gly-Phe-Met-Arg-Phe; MERF), was investigated in radioligand binding assays, [(35)S]GTPgammaS stimulation experiments as well as in in vivo a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::112319ace8ba92f3ef0a431e10febed3
https://doi.org/10.1016/j.regpep.2004.06.017
https://doi.org/10.1016/j.regpep.2004.06.017
Autor:
Margit Szikszay, Gyongyi Horvath, José M. Baeyens, María Ocaña, Willias Masocha, Ahmad Agil, Esperanza Del Pozo
Publikováno v:
Journal of Pharmacology and Experimental Therapeutics. 306:1122-1128
We evaluated the modulation by Na+,K+-ATPase inhibitors of morphine-induced antinociception in the tail-flick test and [3H]naloxone binding to forebrain membranes. The antinociception induced by morphine (1-32 mg/kg, s.c.) in mice was dose-dependentl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c9b2e6fed4eb0e3884562c2842a9c4f9
https://doi.org/10.1124/jpet.103.052977
https://doi.org/10.1124/jpet.103.052977
Autor:
Gabriella Joo, Gyongyi Horvath, W. Klimscha, Gabriella Kekesi, György Benedek, Margit Szikszay, Ildiko Dobos
Publikováno v:
Anesthesiology. 93:231-241
Background The spinal administration of some N-methyl-d-aspartate receptor antagonists results in antinociception and potentiates the effects of opioids and alpha2-adrenoceptor agonists, but ketamine and its enantiomers have not been examined. The pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c00b1903d58f3b2820ba1f42cf0c212
https://doi.org/10.1097/00000542-200007000-00034
https://doi.org/10.1097/00000542-200007000-00034
Publikováno v:
Pharmacological Research. 35:561-568
The antinociceptive and motor effects of the hydrophilic α2-adrenoceptor agonist ST-91 were studied after intrathecal administration to male Wistar rats in different heat–pain tests and different test settings. Intrathecal administration of ST-91
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::46b559f9be548b6e49063b4fce3a0c41
https://doi.org/10.1006/phrs.1997.0188
https://doi.org/10.1006/phrs.1997.0188
Publikováno v:
Journal of Pharmacological and Toxicological Methods. 32:215-218
We describe a simple, noninvasive, nontraumatic, and reproducible ultrasonographic method to determine the effect of the alpha 2-adrenoceptor agonist dexmedetomidine in anesthetic dose (300 micrograms/kg subcutaneously) on the micturition reflex in i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::091b6b8daba09b04138415abb04d090c
https://doi.org/10.1016/1056-8719(94)90090-6
https://doi.org/10.1016/1056-8719(94)90090-6
Publikováno v:
European Journal of Pharmacology. 253:61-66
A comparison was made of the dose-effect relationship of intrathecally applied dexmedetomidine as concerns its mydriatic and antinociceptive effects in rats. Pupil diameter was measured with a photographic method without anesthesia. Antinociception w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d54d3acdc25eeda3f334c104041666b0
https://doi.org/10.1016/0014-2999(94)90757-9
https://doi.org/10.1016/0014-2999(94)90757-9
Publikováno v:
Acta Anaesthesiologica Scandinavica. 36:170-174
An investigation was made of the hypnotic-anaesthetic effects in rats of subcutaneous coadministration of fentanyl (25-100 micrograms.kg-1), clonidine (100-300 micrograms.kg-1) and verapamil (1-5 mg.kg-1). Hypnotic-anaesthetic efficacy was assessed v
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::486bba5875ad3e3c87a9d537aa8a1a25
https://doi.org/10.1111/j.1399-6576.1992.tb03446.x
https://doi.org/10.1111/j.1399-6576.1992.tb03446.x
Publikováno v:
Life Sciences. 50:PL215-PL220
The effects of the combinations of dexmedetomidine-fentanyl and dexmedetomidine-diazepam on the righting reflex were studied in rats. The doses that block the righting reflex for the agents given alone and for their combinations were determined with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f894b6a8ab886507e884d8678d889872
https://doi.org/10.1016/0024-3205(92)90071-v
https://doi.org/10.1016/0024-3205(92)90071-v
Autor:
Gabriella Fábián, B. Tombor, Mária Szűcs, G Emese Kicsi, Gyongyi Horvath, Ildikó Németh, Margit Szikszay
Publikováno v:
Acta biologica Hungarica. 54(2)
Morphine was provided to rats in drinking water for 21 days. Profound analgesic tolerance was detected both in hot-plate and tail-flick tests. The density of [3H]DAMGO binding sites increased by 76% in spinal cord membranes due to morphine exposure c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e77d88db0a70558158d5e584eb70a700
https://pubmed.ncbi.nlm.nih.gov/14535621
https://pubmed.ncbi.nlm.nih.gov/14535621
Publikováno v:
Life sciences. 65(24)
Endomorphin-1 and endomorphin-2 were recently postulated to be endogenous mu-opioid receptor agonists. We have investigated the antinociceptive and antihyperalgesic effects of intrathecally administered endomorphins in cumulative doses (0.1-100 micro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7aa37a9cb10d4fdf9011e3b364d5af4d
https://pubmed.ncbi.nlm.nih.gov/10619371
https://pubmed.ncbi.nlm.nih.gov/10619371