Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Margit Nuetzel"'
Autor:
Roger Mulet-Lazaro, Stanley van Herk, Margit Nuetzel, Aniko Sijs-Szabo, Noelia Díaz, Katherine Kelly, Claudia Erpelinck-Verschueren, Lucia Schwarzfischer-Pfeilschifter, Hanna Stanewsky, Ute Ackermann, Dagmar Glatz, Johanna Raithel, Alexander Fischer, Sandra Pohl, Anita Rijneveld, Juan M. Vaquerizas, Christian Thiede, Christoph Plass, Bas J. Wouters, Ruud Delwel, Michael Rehli, Claudia Gebhard
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-22 (2024)
Abstract Leukemias with ambiguous lineage comprise several loosely defined entities, often without a clear mechanistic basis. Here, we extensively profile the epigenome and transcriptome of a subgroup of such leukemias with CpG Island Methylator Phen
Externí odkaz:
https://doaj.org/article/df577d6f414846109f3f3dcf2f2865a4
Autor:
Julia Minderjahn, Alexander Fischer, Konstantin Maier, Karina Mendes, Margit Nuetzel, Johanna Raithel, Hanna Stanewsky, Ute Ackermann, Robert Månsson, Claudia Gebhard, Michael Rehli
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-19 (2022)
How chromatin structure and gene accessibility changes during monocyte differentiation is not clearly defined. Here the authors characterize the chromatin changes during macrophage or dendritic cell maturation from monocytes and the dependence of thi
Externí odkaz:
https://doaj.org/article/9b3ed1fbfa844e7484ae6ceb15b31a69
Autor:
Uwe Schwartz, Tetsuro Komatsu, Claudia Huber, Floriane Lagadec, Conradin Baumgartl, Elisabeth Silberhorn, Margit Nuetzel, Fabienne Rayne, Eugenia Basyuk, Edouard Bertrand, Michael Rehli, Harald Wodrich, Gernot Längst
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::edb4133b6acf694c9d7aaddf3f4b4d38
https://doi.org/10.15252/rc.2023868322
https://doi.org/10.15252/rc.2023868322
Autor:
Uwe Schwartz, Tetsuro Komatsu, Claudia Huber, Floriane Lagadec, Conradin Baumgartl, Elisabeth Silberhorn, Margit Nuetzel, Fabienne Rayne, Eugenia Basyuk, Edouard Bertrand, Michael Rehli, Harald Wodrich, Gernot Laengst
SUMMARYWithin the virion, adenovirus DNA associates with the virus-encoded, protamine-like structural protein pVII. Whether this association is organized, and how genome packaging changes during infection and subsequent transcriptional activation is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::210f805a824627580793f58235d99ce9
https://doi.org/10.1101/2020.07.07.190926
https://doi.org/10.1101/2020.07.07.190926
Autor:
Sebastian Stasik, Reinhard Andreesen, Gerhard Ehninger, Michael Rehli, Lucia Schwarzfischer, Claudia Gebhard, Daniel Heudobler, Julia Wimmer, Dagmar Glatz, Christian Thiede, Margit Nuetzel
Publikováno v:
Leukemia. 33(1)
Malignant transformation is frequently associated with disease-specific epigenetic alterations, but the underlying mechanisms and pathophysiological consequences remain poorly understood. Here, we used global comparative DNA methylation profiling at
Autor:
Margit Nuetzel, Dagmar Glatz, Gerhard Ehninger, Claudia A.J. Erpelinck-Verschueren, Stanley van Herk, Bas J. Wouters, Claudia Gebhard, Lucia Schwarzfischer, Wolfgang Herr, Michael Rehli, Daniel Heudobler, Sandra Pohl, Roger Mulet-Lazaro, Christian Thiede, Ruud Delwel
Publikováno v:
Blood. 132:2608-2608
Acute myeloid leukemia (AML) represents a highly heterogeneous myeloid stem cell disorder classified based on various genetic defects. Besides genetic alterations, epigenetic changes are recognized as an additional mechanism contributing to leukemoge