Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Margit Hornof"'
Autor:
Claudia Kuntner, Daniel Dangl, Oliver Langer, Martin Hoffer, Herbert Kvaternik, Thomas Wanek, Margit Hornof
Publikováno v:
Molecular Imaging and Biology. 13:222-226
The polysaccharide chitosan is a unique material for the design of ocular drug-delivery vehicles. The aim of this study was to radiolabel chitosan with iodine-124 ((124)I) for measurement of ocular pharmacokinetics in rabbits using small-animal posit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c7ce678ad9c7f8695d906f72944f4fc5
https://doi.org/10.1007/s11307-010-0352-7
https://doi.org/10.1007/s11307-010-0352-7
Autor:
Maxim Antopolsky, Astrid Subrizi, Veli-Pekka Ranta, Antti Laukkanen, Lasse Murtomäki, Margit Hornof, Eliisa Mannermaa, Kirsi Lummepuro, Arto Urtti
Publikováno v:
JOURNAL OF CONTROLLED RELEASE. 148(1):42-48
Periocular administration is a potential way of delivering drugs to their targets in posterior eye segment (vitreous, neural retina, retinal pigment epithelium (RPE), choroid). Purpose of this study was to evaluate the role of the barriers in periocu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00ac64d5897b83bbcc88678cb9644e47
http://juuli.fi/Record/0336741310
http://juuli.fi/Record/0336741310
Publikováno v:
Acta Ophthalmologica. 86:91-96
Purpose: The use of biopolymers in peribulbar injection for controlled drug delivery provides alternative options to eyedrops and intravitreal or surgical methods. Polymerizable biopolymers are especially likely to have a role because of their partic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b44177ebb7d2f3a692d9dbf360e412f
https://doi.org/10.1111/j.1600-0420.2007.01001.x
https://doi.org/10.1111/j.1600-0420.2007.01001.x
Publikováno v:
The Journal of Gene Medicine. 10:70-80
Aim It was the aim of this study to prepare purified DNA/PEI polyplexes, which are coated with hyaluronan to facilitate CD44 receptor mediated uptake of the DNA/PEI polyplex and to reduce unspecific interactions of the complex with negatively charged
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::088e24f12d389e143f712735ca79cbf4
https://doi.org/10.1002/jgm.1125
https://doi.org/10.1002/jgm.1125
Publikováno v:
European Journal of Pharmaceutics and Biopharmaceutics. 57:9-17
The derivatization of the primary amino groups of chitosan with coupling reagents bearing thiol functions leads to the formation of thiolated chitosans. So far, three types of thiolated chitosans have been generated: chitosan-cysteine conjugates, chi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::74d588470682ef8f13ee600adbe64f2d
https://doi.org/10.1016/s0939-6411(03)00147-4
https://doi.org/10.1016/s0939-6411(03)00147-4
Publikováno v:
Scientia Pharmaceutica
Volume 71
Issue 3
Pages 165-177
Pages 255-267
Volume 71
Issue 3
Pages 165-177
Pages 255-267
It was the aim of this study to develop an oral phosphorothioate oligodeoxynucleotide (PS-ODN) drug delivery system and to evaluate its properties in vitro. Results demonstrated that the 16-mer phosphorothioate oligonucleotide used was completely sta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::156f5317a113bc9974c3cf91b19e089f
https://doi.org/10.3797/scipharm.aut-03-17
https://doi.org/10.3797/scipharm.aut-03-17
Publikováno v:
Journal of controlled release
The aim of the study was to develop a mucoadhesive ocular insert for the controlled delivery of ophthalmic drugs and to evaluate its efficacy in vivo. The inserts tested were based either on unmodified or thiolated poly(acrylic acid). Water uptake an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d2eeb77584dfc83ed1f7e05169603258
https://doi.org/10.1016/s0168-3659(03)00135-4
https://doi.org/10.1016/s0168-3659(03)00135-4
Publikováno v:
European Journal of Pharmaceutics and Biopharmaceutics. 55:185-190
The aim of this study was to evaluate the viscoelastic properties of chitosan-thioglycolic acid conjugates with different amounts of thiol groups immobilized on the polymer. The modification of chitosan was achieved via the covalent attachment of thi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea9664f17a63c2e9bfc11e05f153bacd
https://doi.org/10.1016/s0939-6411(02)00162-5
https://doi.org/10.1016/s0939-6411(02)00162-5
Publikováno v:
American Journal of Drug Delivery. 1:241-254
Within recent years the level of interest in both local and systemic vaginal drug delivery systems has increased considerably. The vagina offers numerous advantages as a site for drug delivery, such as convenient access, prolonged retention of formul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::72f7d02ff69782a7490e532c629d716f
https://doi.org/10.2165/00137696-200301040-00003
https://doi.org/10.2165/00137696-200301040-00003
Publikováno v:
Journal of Pharmaceutical Sciences. 91:2588-2592
It was the aim of this study to investigate the permeation enhancing effect of thiolated polycarbophil on the cornea of rabbits in vitro. The proposed reaction mechanism involves the opening of the tight junctions in the corneal epithelium. The modif
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::55548ad0e591c231deead53510691f20
https://doi.org/10.1002/jps.10258
https://doi.org/10.1002/jps.10258