Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Margit, Dlaska"'
Publikováno v:
Clinical chemistry and laboratory medicineReferences. 60(10)
Publikováno v:
DNA and Cell Biology. 27:489-496
The end of linear chromosomes forms a lasso-like structure called the t-loop. Such t-loops resemble a DNA recombination intermediate, where the single-stranded 3' overhang is arrested in a stretch of duplex DNA. Presumably, such a t-loop can also be
Autor:
Günther Sperk, Thomas Czech, Margit Dlaska, Christoph Baumgartner, Susanne Pirker, Christine E. Bandtlow
Publikováno v:
European Journal of Neuroscience. 20:195-206
Mesial temporal lobe epilepsy (TLE) is associated with pronounced anatomical and biochemical changes in the hippocampal formation including extensive neurodegeneration, reorganization of mossy fibres and sprouting of interneurons. Although the anatom
Publikováno v:
Cell cycle (Georgetown, Tex.). 12(13)
Immortal cells require a mechanism of telomere length control in order to divide infinitely. One mechanism is telomerase, an enzyme that compensates the loss of telomeric DNA. The second mechanism is the alternative lengthening of telomeres (ALT) pat
Autor:
Ewald, Wöll, Richard, Greil, Wolfgang, Eisterer, Oliver, Bechter, Michael A, Fridrik, Birgit, Grünberger, August, Zabernigg, Beate, Mayrbäurl, Gudrun, Russ, Margit, Dlaska, Peter, Obrist, Josef, Thaler
Publikováno v:
Anticancer research. 31(12)
Patients suffering from advanced gastric cancer still have a poor prognosis and treatment options are limited. In our previous phase II trial (AGMT-Gastric-1), we showed that the combination of oxaliplatin and irinotecan was well tolerated and effect
Autor:
Eberhard Gunsilius, Wolfgang Hilbe, Margit Dlaska, Thomas Schmid, Andreas Pircher, Christian M. Kähler, Gerold Kawaguchi, Sergej Skvortsov
Publikováno v:
Oncology reports. 19(2)
Bone marrow-derived endothelial progenitor cells (EPC) play an important role in neovascularisation and tumor growth. However, the clinical relevance of EPCs on blood vessel formation in non-small cell lung cancer (NSCLC) is unclear. EPC numbers in c
Publikováno v:
Cancer detection and prevention. 30(5)
Background : S100 A2 and hnRNP A2/B1 (heterogeneous ribonucleoprotein A2/B1) with its splicing variant hnRNP B1 are proteins which are involved in cellular proliferation, differentiation and protein synthesis and are up-regulated in non-small cell lu
Autor:
Stephan Dirnhofer, Margit Dlaska, Wolfgang Hilbe, Wolfgang Eisterer, Thomas Kühr, Ewald Wöll, Andreas Mildner, Hans-Christoph Duba, Thomas Schmid, Frieda Oberwasserlechner
Publikováno v:
International Journal of Oncology.
A real-time PCR technique with automated computerized analysis (TaqMan ) was tested to detect K-ras mutations in 66 patients suffering from NSCLC. This technology is characterized by high reproducibility of data and a time-saving analysis procedure.
Publikováno v:
Experimental hematology. 30(1)
Objective Expression of the catalytic subunit of the telomerase enzyme hTERT is essential for prolonging the replicative lifespan and is the rate-limiting step in cellular immortalization and carcinogenesis. Because hTERT expression is positively cor
Autor:
Margit Dlaska, Oliver Bechter
Publikováno v:
Cancer Research. 71:2993-2993
Telomere homeostasis is a hallmark of malignancy and occurs via two different mechanisms. The first mechanism is telomere length control via telomerase activity, the second mechanism is characterized by the lack of any detectable telomerase activity