Zobrazeno 1 - 10
of 118
pro vyhledávání: '"Margherita Sosio"'
Autor:
Muriel Schicketanz, Magdalena Petrová, Dominik Rejman, Margherita Sosio, Stefano Donadio, Yong Everett Zhang
Publikováno v:
Microbial Cell, Vol 11, Pp 312-320 (2024)
The alarmone (p)ppGpp serves as the signalling molecule for the bacterial universal stringent response and plays a crucial role in bacterial virulence, persistence, and stress adaptation. Consequently, there is a significant focus on developing new d
Externí odkaz:
https://doaj.org/article/e36588ede6674f2c8d9d6efb2858b636
Autor:
Meng Zhang, Liyuan Kong, Rong Gong, Marianna Iorio, Stefano Donadio, Zixin Deng, Margherita Sosio, Wenqing Chen
Publikováno v:
Microbial Cell Factories, Vol 21, Iss 1, Pp 1-14 (2022)
Abstract Epidemic diseases and antibiotic resistance are urgent threats to global health, and human is confronted with an unprecedented dilemma to conquer them by expediting development of new natural product related drugs. C-nucleoside antibiotics,
Externí odkaz:
https://doaj.org/article/c357c28ab54740d0832594e27c3cffa3
Blocks in the pseudouridimycin pathway unlock hidden metabolites in the Streptomyces producer strain
Autor:
Marianna Iorio, Sahar Davatgarbenam, Stefania Serina, Paolo Criscenzo, Mitja M. Zdouc, Matteo Simone, Sonia I. Maffioli, Richard H. Ebright, Stefano Donadio, Margherita Sosio
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-11 (2021)
Abstract We report a metabolomic analysis of Streptomyces sp. ID38640, a soil isolate that produces the bacterial RNA polymerase inhibitor pseudouridimycin. The analysis was performed on the wild type, on three newly constructed and seven previously
Externí odkaz:
https://doaj.org/article/bf5c6c742b4b4ec79d73fdd145693768
Autor:
Francesco Del Carratore, Marianna Iorio, Mercedes Pérez-Bonilla, Kamila Schmidt, Rosario Pérez-Redondo, Margherita Sosio, Sandy J. Macdonald, Ivan S. Gyulev, Areti Tsigkinopoulou, Gavin H. Thomas, Olga Genilloud, Antonio Rodríguez-García, Stefano Donadio, Rainer Breitling, Eriko Takano
Publikováno v:
mSystems, Vol 6, Iss 3 (2021)
Planobispora roseaClostridium difficile
Externí odkaz:
https://doaj.org/article/b13f656c6d6648a387ac1fe4e2817f64
Publikováno v:
Frontiers in Microbiology, Vol 12 (2021)
Externí odkaz:
https://doaj.org/article/a150ba079d4542718afcc080968ad48f
Autor:
Marianna Iorio, Arianna Tocchetti, Joao Carlos Santos Cruz, Giancarlo Del Gatto, Cristina Brunati, Sonia Ilaria Maffioli, Margherita Sosio, Stefano Donadio
Publikováno v:
Antibiotics, Vol 7, Iss 2, p 47 (2018)
In screening for novel antibiotics, an attractive element of novelty can be represented by screening previously underexplored groups of microorganisms. We report the results of screening 200 strains belonging to the actinobacterial genus Actinoallomu
Externí odkaz:
https://doaj.org/article/85195c37ead6440699c5ff9bca65052e
Publikováno v:
Antibiotics, Vol 7, Iss 2, p 30 (2018)
Glycopeptides (GPAs) are an important class of antibiotics, with vancomycin and teicoplanin being used in the last 40 years as drugs of last resort to treat infections caused by Gram-positive pathogens, including methicillin-resistant Staphylococcus
Externí odkaz:
https://doaj.org/article/2d04d22f32e441efa31d222951dcca8e
Autor:
Arianna Tocchetti, Roberta Bordoni, Giuseppe Gallo, Luca Petiti, Giorgio Corti, Silke Alt, Joao C S Cruz, Anna Maria Salzano, Andrea Scaloni, Anna Maria Puglia, Gianluca De Bellis, Clelia Peano, Stefano Donadio, Margherita Sosio
Publikováno v:
PLoS ONE, Vol 10, Iss 7, p e0133705 (2015)
We report the genome sequence of Planobispora rosea ATCC 53733, a mycelium-forming soil-dweller belonging to one of the lesser studied genera of Actinobacteria and producing the thiopeptide GE2270. The P. rosea genome presents considerable convergenc
Externí odkaz:
https://doaj.org/article/c70781536b33424ca81d8a7674fd745c
Publikováno v:
PLoS ONE, Vol 9, Iss 3, p e90499 (2014)
GE2270 is a thiopeptide antibiotic generated by extensive posttranslational modifications of a ribosomally generated precursor peptide. Thiopeptides are especially active against Gram-positive bacteria, including methicillin resistant Staphylococcus
Externí odkaz:
https://doaj.org/article/572910af41d147d0adcaa4d341a6d106
Autor:
Kristiina Vind, Cristina Brunati, Matteo Simone, Margherita Sosio, Stefano Donadio, Marianna Iorio
Publikováno v:
Acs Chemical Biology 18 (2023) 4
Acs Chemical Biology, 18(4), 861-874
Acs Chemical Biology, 18(4), 861-874
Streptomycetes are bacteria known for their extraordinary biosynthetic capabilities. Herein, we describe the genome and metabolome of a particularly talented strain, Streptomyces ID71268. Its 8.4-Mbp genome harbors 32 bioinformatically predicted bios
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c3043c661fca71713df0f990abaa2fa8
https://doi.org/10.1021/acschembio.2c00958
https://doi.org/10.1021/acschembio.2c00958