Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Margherita Sonnessa"'
Autor:
Margherita Sonnessa, Sara Sergio, Concetta Saponaro, Michele Maffia, Daniele Vergara, Francesco Alfredo Zito, Andrea Tinelli
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
Gynecological cancer management remains challenging and a better understanding of molecular mechanisms that lead to carcinogenesis and development of these diseases is needed to improve the therapeutic approaches. The Na+/H+ exchanger regulatory fact
Externí odkaz:
https://doaj.org/article/e991a8d8bf2641999dfed4207cd6b666
Autor:
Concetta Saponaro, Emanuela Scarpi, Margherita Sonnessa, Antonella Cioffi, Francesca Buccino, Francesco Giotta, Maria Irene Pastena, Francesco Alfredo Zito, Anita Mangia
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
Inflammasome complexes play a pivotal role in different cancer types. NOD-like receptor protein 3 (NLRP3) inflammasome is one of the most well-studied inflammasomes. Activation of the NLRP3 inflammasome induces abnormal secretion of soluble cytokines
Externí odkaz:
https://doaj.org/article/be8e5b059b7a4fb2ac3de55b5ca89664
Autor:
Concetta Saponaro, Annarita Fanizzi, Margherita Sonnessa, Paolo Mondelli, Daniele Vergara, Donato Loisi, Raffaella Massafra, Agnese Latorre, Francesco A. Zito, Laura Schirosi
Publikováno v:
Pharmaceuticals, Vol 15, Iss 6, p 651 (2022)
Inflammasomes are protein complexes involved in the regulation of different biological conditions. Over the past few years, the role of NLRP3 in different tumor types has gained interest. In breast cancer (BC), NLRP3 has been associated with multiple
Externí odkaz:
https://doaj.org/article/30f836eaad17433698bbc277a5b2fc64
Autor:
Margherita Sonnessa, Antonella Cioffi, Oronzo Brunetti, Nicola Silvestris, Francesco A. Zito, Concetta Saponaro, Anita Mangia
Publikováno v:
Frontiers in Oncology, Vol 10 (2020)
The tumor microenvironment (TME) is crucial in cancer onset, progression and response to treatment. It is characterized by an intricate interaction of immune cells and cytokines involved in tumor development. Among these, inflammasomes are oligomeric
Externí odkaz:
https://doaj.org/article/708cf7e405d342b1995ef4ed5bd9402f
Autor:
Michele Guida, Alessandro D'Alò, Anita Mangia, Federica Di Pinto, Margherita Sonnessa, Anna Albano, Angela Sciacovelli, Artor Niccoli Asabella, Livia Fucci
Publikováno v:
Frontiers in Oncology, Vol 10 (2020)
Background: Merkel-cell carcinoma (MCC) is a rare, highly aggressive skin cancer typically involving elderly people. Surgery is usually the first treatment for primary tumor. In adjuvant setting, radiotherapy is effective in reducing local recurrence
Externí odkaz:
https://doaj.org/article/1724d0b7dc3a488ab1313dff87cf88b2
Autor:
Nicola Silvestris, Fulvia Colonna, Antonio Giovanni Solimando, Sabina Delcuratolo, Concetta Saponaro, Aldo Scarpa, Livia Fucci, Margherita Sonnessa, Claudio Luchini, Floriana Nappo, Antonella Argentiero, Sara Lonardi, Matteo Fassan, Oronzo Brunetti
Publikováno v:
Expert Opinion on Therapeutic Targets. 25:1007-1016
Background The improved immunological understanding revealed the tumor microenvironment as an appealing driver to restore the immune response against cancer cells resulting in a paradigm shift in the oncology field. However, the complexity of the tum
Autor:
Hajar Alemohammad, Basira Najafzadeh, Zahra Asadzadeh, Amir Baghbanzadeh, Farid Ghorbaninezhad, Arezoo Najafzadeh, Hossein Safarpour, Renato Bernardini, Oronzo Brunetti, Margherita Sonnessa, Rossella Fasano, Nicola Silvestris, Behzad Baradaran
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 146, Iss, Pp 112516-(2022)
The growth and development of cancer are directly correlated to the suppression of the immune system. A major breakthrough in cancer immunotherapy depends on various mechanisms to detect immunosuppressive factors that inhibit anti-tumor immune respon
Autor:
Angela Monica Sciacovelli, Anna Albano, Livia Fucci, Michele Guida, Anita Mangia, Federica Di Pinto, Alessandro D'Alo', Margherita Sonnessa, Artor Niccoli Asabella
Publikováno v:
Frontiers in Oncology, Vol 10 (2020)
Frontiers in Oncology
Frontiers in Oncology
Background: Merkel-cell carcinoma (MCC) is a rare, highly aggressive skin cancer typically involving elderly people. Surgery is usually the first treatment for primary tumor. In adjuvant setting, radiotherapy is effective in reducing local recurrence