Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Margherita Maggioni"'
Autor:
Margherita Maggioni, Monica Barbero, Fabrizio Barpi, Mauro Borri-Brunetto, Valerio De Biagi, Michele Freppaz, Barbara Frigo, Oronzo Pallara, Bernardino Chiaia
Publikováno v:
Geosciences, Vol 9, Iss 11, p 471 (2019)
In full-scale snow avalanche test sites, structures such as pylons, plates, or dams have been used to measure impact forces and pressures from avalanches. Impact pressures are of extreme importance when dealing with issues such as hazard mapping and
Externí odkaz:
https://doaj.org/article/23c83ceef7d04e27a96694613cab00a6
Autor:
Maria Fazzari, Giulia Lunghi, Pamela Fato, Maura Samarani, Erika Di Biase, Maria Grazia Ciampa, Diego Yuri Pomè, Simona Prioni, Manuela Valsecchi, Margherita Maggioni, Sandro Sonnino, Elena Chiricozzi, Laura Mauri
Publikováno v:
Glycoconjugate Journal. 37:329-343
It has been recently reported by our group that GM1-oligosaccharide added to neuroblastoma cells or administered to mouse experimental model mimics the neurotrophic and neuroprotective properties of GM1 ganglioside. In addition to this, differently f
Autor:
Elena Chiricozzi, Margherita Maggioni, Maria Fazzari, Erika Di Biase, Pamela Fato, Gianluca Verlengia, Gusheng Wu, Diego Yuri Pomè, Simona Prioni, Giulia Lunghi, Laura Mauri, Stefano Cattaneo, Robert Assini, Sandro Sonnino, Robert W. Ledeen, Nicoletta Loberto, Samar K. Alselehdar, Manuela Valsecchi, Maria Grazia Ciampa
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-15 (2019)
Scientific Reports
Scientific Reports
Given the recent in vitro discovery that the free soluble oligosaccharide of GM1 is the bioactive portion of GM1 for neurotrophic functions, we investigated its therapeutic potential in the B4galnt1+/− mice, a model of sporadic Parkinson’s diseas
Autor:
Margherita Maggioni, Michele Freppaz, Giovanni Martino Bombelli, Daniele Bocchiola, Gabriele Confortola
Publikováno v:
Climate, Vol 9, Iss 171, p 171 (2021)
Climate; Volume 9; Issue 12; Pages: 171
Climate; Volume 9; Issue 12; Pages: 171
Snow gliding, a slow movement downhill of snow cover, is complex to forecast and model and yet is extremely important, because it drives snowpack dynamics in the pre-avalanching phase. Despite recent interest in this process and the development of so
Autor:
Laura Mauri, Margherita Maggioni, Elena Chiricozzi, Maria Fazzari, Diego Yuri Pomè, Sandro Sonnino, Giulia Lunghi, Nicoletta Loberto, Riccardo Casellato, Erika Di Biase
Publikováno v:
Journal of Neurochemistry. 149:231-241
Recently, we highlighted that the ganglioside GM1 promotes neuroblastoma cells differentiation by activating the TrkA receptor through the formation of a TrkA-GM1 oligosaccharide complex at the cell surface. To study the TrkA-GM1 interaction, we synt
Autor:
Elena Chiricozzi, Maria Fazzari, Erika Di Biase, Margherita Maggioni, Nicoletta Loberto, Francesca Grassi Scalvini, Gabriella Tedeschi, Maffioli Elisa, Sandro Sonnino, Giulia Lunghi
Publikováno v:
Molecular Neurobiology. 56:6673-6702
Recently, we demonstrated that the GM1 oligosaccharide, II3Neu5Ac-Gg4 (OligoGM1), administered to cultured murine Neuro2a neuroblastoma cells interacts with the NGF receptor TrkA, leading to the activation of the ERK1/2 downstream pathway and to cell
Autor:
Erika Di Biase, Giulia Lunghi, Margherita Maggioni, Maria Fazzari, Diego Yuri Pomè, Nicoletta Loberto, Maria Grazia Ciampa, Pamela Fato, Laura Mauri, Emmanuel Sevin, Fabien Gosselet, Sandro Sonnino, Elena Chiricozzi
Publikováno v:
International Journal of Molecular Sciences
International Journal of Molecular Sciences, MDPI, 2020, 21 (8), pp.2858. ⟨10.3390/ijms21082858⟩
International Journal of Molecular Sciences, Vol 21, Iss 2858, p 2858 (2020)
International Journal of Molecular Sciences, MDPI, 2020, 21 (8), pp.2858. ⟨10.3390/ijms21082858⟩
International Journal of Molecular Sciences, Vol 21, Iss 2858, p 2858 (2020)
International audience; Ganglioside GM1 (GM1) has been reported to functionally recover degenerated nervous system in vitro and in vivo, but the possibility to translate GM1's potential in clinical settings is counteracted by its low ability to overc
On 18 January 2017 a catastrophic avalanche destroyed the Rigopiano Gran Sasso Resort & Wellness (Rigopiano Hotel) in the Gran Sasso National Park in Italy, with 40 people trapped and a death toll of 29. This article describes the location of the dis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bad99d705d4852f9cfb7c4e7d1068659
http://hdl.handle.net/11583/2855671
http://hdl.handle.net/11583/2855671
Autor:
Sandro Sonnino, Luca Palazzolo, Nicoletta Loberto, Ivano Eberini, Diego Yuri Pomè, Chiara Parravicini, Elena Chiricozzi, Erika Di Biase, Margherita Maggioni
Publikováno v:
Journal of Neurochemistry. 143:645-659
GM1 ganglioside (II3 NeuAc-Gg4 Cer) is known to promote neurite formation in neuroblastoma cells by activating TrkA-MAPK pathway. The molecular mechanism by which GM1 is involved in the neurodifferentiation process is still unknown, however, in vitro