Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Margherita M. Botto"'
Publikováno v:
ACS Omega. 8:8285-8292
Exonucleases are essential enzymes that remove nucleotides from free DNA ends during DNA replication, DNA repair and telomere maintenance. Due to their essential role, they are potential targets for novel anticancer and antimicrobial drugs but have s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9d3c40ce112e409935f94c37ff3bf0f6
https://doi.org/10.1101/2022.09.12.507544
https://doi.org/10.1101/2022.09.12.507544
DNA replication introduces thousands of RNA primers into the lagging strand that need to be removed for replication to be completed. In Escherichia coli when the replicative DNA polymerase Pol IIIα terminates at a previously synthesized RNA primer,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4042d094d446903bf42dbc29e017cb80
https://doi.org/10.1101/2022.08.02.502465
https://doi.org/10.1101/2022.08.02.502465
Autor:
Brouwer T; Biological and Soft Matter Physics, Huygens-Kamerlingh Onnes Laboratory, Leiden University, Niels Bohrweg 2, 2333 CA Leiden, The Netherlands., Pham C; Biological and Soft Matter Physics, Huygens-Kamerlingh Onnes Laboratory, Leiden University, Niels Bohrweg 2, 2333 CA Leiden, The Netherlands., Kaczmarczyk A; Biological and Soft Matter Physics, Huygens-Kamerlingh Onnes Laboratory, Leiden University, Niels Bohrweg 2, 2333 CA Leiden, The Netherlands., de Voogd WJ; Biological and Soft Matter Physics, Huygens-Kamerlingh Onnes Laboratory, Leiden University, Niels Bohrweg 2, 2333 CA Leiden, The Netherlands., Botto M; Biological and Soft Matter Physics, Huygens-Kamerlingh Onnes Laboratory, Leiden University, Niels Bohrweg 2, 2333 CA Leiden, The Netherlands., Vizjak P; Biomedical Center, Ludwig-Maximilians-Universität München, 82152 Martinsried, Germany., Mueller-Planitz F; Biomedical Center, Ludwig-Maximilians-Universität München, 82152 Martinsried, Germany.; Institute of Physiological Chemistry, Faculty of Medicine Carl Gustav Carus, Technische Universität Dresden, Fetscherstraße 74, 01307 Dresden, Germany., van Noort J; Biological and Soft Matter Physics, Huygens-Kamerlingh Onnes Laboratory, Leiden University, Niels Bohrweg 2, 2333 CA Leiden, The Netherlands.
Publikováno v:
Nucleic acids research [Nucleic Acids Res] 2021 Mar 18; Vol. 49 (5), pp. 2537-2551.
Autor:
Dodd T; Department of Chemistry, Georgia State University, Atlanta, GA, USA.; Center for Diagnostics and Therapeutics, Georgia State University, Atlanta, GA, USA., Botto M; Department of Cell and Chemical Biology, Leiden University Medical Center, Leiden, The Netherlands., Paul F; Department of Biochemistry & Molecular Biology, University of Chicago, Chicago, IL, USA., Fernandez-Leiro R; Spanish National Cancer Research Centre (CNIO), Madrid, Spain., Lamers MH; Department of Cell and Chemical Biology, Leiden University Medical Center, Leiden, The Netherlands. m.h.lamers@lumc.nl., Ivanov I; Department of Chemistry, Georgia State University, Atlanta, GA, USA. iivanov@gsu.edu.; Center for Diagnostics and Therapeutics, Georgia State University, Atlanta, GA, USA. iivanov@gsu.edu.
Publikováno v:
Nature communications [Nat Commun] 2020 Oct 23; Vol. 11 (1), pp. 5379. Date of Electronic Publication: 2020 Oct 23.