Cholesterol re-organisation and lipid de-packing by arginine-rich cell penetrating peptides: Role in membrane translocation.

Autor: Claudia Almeida, Ofelia Maniti, Margherita Di Pisa, Jean-Marie Swiecicki, Jesus Ayala-Sanmartin

Publikováno v: PLoS ONE, Vol 14, Iss 1, p e0210985 (2019)

Cell penetrating peptides (CPPs) are able to transport hydrophilic molecules inside cells. To reach the cytosol, the peptide associated with a cargo must cross the plasma or the endosomal membrane. Different molecular mechanisms for peptide internali

Externí odkaz: https://doaj.org/article/c9894f7ed1494acba04a45f9ad8e5937

A Multiple N-Glucosylated Peptide Epitope Efficiently Detecting Antibodies in Multiple Sclerosis

Autor: Giuseppina Sabatino, Barbara Mulinacci, Francesca Nuti, Margherita Di Pisa, Caterina Tiberi, Ilaria Paolini, Roberta Lanzillo, E. Peroni, Paolo Rovero, Anna Maria Papini, Feliciana Real Fernández, Martina Petruzzo, Francesco Lolli, Vincenzo Brescia Morra

Publikováno v: Brain Sciences, Vol 10, Iss 453, p 453 (2020)
Brain Sciences
Volume 10
Issue 7
Brain sciences 10 (2020). doi:10.3390/brainsci10070453
info:cnr-pdr/source/autori:Nuti, Francesca; Fernandez, Feliciana Real; Sabatino, Giuseppina; Peroni, Elisa; Mulinacci, Barbara; Paolini, Ilaria; Di Pisa, Margherita; Tiberi, Caterina; Lolli, Francesco; Petruzzo, Martina; Lanzillo, Roberta; Morra, Vincenzo Brescia; Rovero, Paolo; Papini, Anna Maria/titolo:A Multiple N-Glucosylated Peptide Epitope Efficiently Detecting Antibodies in Multiple Sclerosis/doi:10.3390%2Fbrainsci10070453/rivista:Brain sciences/anno:2020/pagina_da:/pagina_a:/intervallo_pagine:/volume:10

Diagnostics of Multiple Sclerosis (MS) are essentially based on the gold standard magnetic resonance imaging. Few alternative simple assays are available to follow up disease activity. Considering that the disease can remain elusive for years, identi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da865b7dcc1fb69db50d67251a28f406
http://hdl.handle.net/2158/1201654

Accumulation of cell-penetrating peptides in large unilamellar vesicles: A straightforward screening assay for investigating the internalization mechanism

Autor: Margherita Di Pisa, Fabienne Burlina, Christelle Mansuy, Gérard Chassaing, Jean-Marie Swiecicki, Solange Lavielle, Pascaline Lécorché

Publikováno v: Biopolymers. 104:533-543

The internalization of cell-penetrating peptides (CPPs) into liposomes (large unilamellar vesicles, LUVs) was studied with a rapid and robust procedure based on the quenching of a small fluorescent probe, 7-nitrobenz-2-oxa-1,3-diazole (NBD). Quenchin

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::42776841f3012cad2c264bb19283823e
https://doi.org/10.1002/bip.22652

When cationic cell-penetrating peptides meet hydrocarbons to enhance in-cell cargo delivery

Autor: Jean-Marie Swiecicki, Margherita Di Pisa, Gérard Chassaing

Publikováno v: Journal of Peptide Science. 21:356-369

Cell-penetrating peptides (CPPs) are short sequences often rich in cationic residues with the remarkable ability to cross cell membranes. In the past 20 years, CPPs have gained wide interest and have found numerous applications in the delivery of bio

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::a8983a1794955a27f5e864fcd748319f
https://doi.org/10.1002/psc.2755

Electrochemical quenching of the fluorescence produced by NBD-labelled cell penetrating peptides: A contribution to the study of their internalization in large unilamellar vesicles

Autor: Jean-Marie Swiecicki, Eric Labbé, Lylian Challier, Gérard Chassaing, Mathieu Durand, Margherita Di Pisa, Pierluca Messina, Raquel Oliveira, Solange Lavielle, Olivier Buriez

Publikováno v: Journal of Electroanalytical Chemistry
Journal of Electroanalytical Chemistry, Elsevier 2017, 788, pp.225-231. ⟨10.1016/j.jelechem.2017.02.006⟩
Journal of Electroanalytical Chemistry, 2017, 788, pp.225-231. ⟨10.1016/j.jelechem.2017.02.006⟩

International audience; This work investigates the implementation of a simple and versatile electrochemical setup aimed at achieving a fast and complete fluorescence extinction of NBD-labelled (NBD = 7-nitrobenz-2-oxa-1,3-diazole) cell penetrating pe

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cf78d0b25575e6ec220822513a35c65d
https://hal.sorbonne-universite.fr/hal-01469377/file/de_Oliveira_Electrochemical.pdf