Zobrazeno 1 - 10
of 43
pro vyhledávání: '"Margery Nicolson"'
Publikováno v:
Hearing Research. 159:125-131
Immunophilin FK binding protein-12 (FKBP-12), the soluble receptor for the immunosuppressant drug FK506, is involved in a number of neuronal activities including increased nerve regeneration in the peripheral nervous system and enhanced recovery in a
Autor:
M. B. Horlick, Barbara Fedun, Margery Nicolson, Lenore S. Levine, Jack Wang, Michael Rosenbaum, Rudolph L. Leibel, Richard N. Pierson
Publikováno v:
The Journal of Clinical Endocrinology & Metabolism. 85:2509-2518
Circulating concentrations of leptin are better correlated with absolute amounts of adipose tissue [fat mass (FM)] than with relative body fatness (body mass index or percent body fat). There is a clear sexual dimorphism in circulating concentrations
Autor:
Margery Nicolson, Rebecca B. Hill, Nancy F. Butte, William W. Wong, Janice E. Stuff, Elliot O’Brian Smith, Kenneth J. Ellis, Albert C. Hergenroeder
Publikováno v:
The Journal of Clinical Endocrinology & Metabolism. 83:3574-3577
Because African-American girls are heavier, taller, and mature earlier than Caucasian girls, we hypothesized that the serum leptin concentration differs between the two groups. Serum leptin concentrations were measured by immunoassay in 12-h fasted b
Autor:
Gary E. Elliott, Margery Nicolson, Jill A. Crouse, Robert E. Pacifici, Laura Chiu, Larry Bennett, Teresa L. Burgess, Jason Moore
Publikováno v:
Journal of Biological Chemistry. 273:18365-18373
Leptin and the leptin receptor are key players in the regulation of body weight. In an attempt to dissect the molecular mechanism of the Zucker fatty rat leptin receptor mutation (Gln269 --Pro) we analyzed the effects of this mutation on leptin recep
Autor:
Clifford J. Rosen, Johannes D. Veldhuis, Seymour Reichlin, Nancy Lundgren, Margery Nicolson, Joseph J. Kehayias, Ronenn Roubenoff, Laura C. Rall
Publikováno v:
The Journal of Clinical Endocrinology & Metabolism. 83:1502-1506
Sarcopenia, the decline in body cell mass (BCM) and especially in muscle mass with age, is an important age-related cause of frailty and loss of independence in the elderly. Because the decline in BCM with age parallels a decline in GH secretion from
Publikováno v:
American Journal of Medical Genetics. 75:7-12
Prader-Willi syndrome (PWS) is characterized by early childhood obesity, mental deficiency, hypogonadism, hypotonia, hypopigmentation, short stature, small hands and feet, and a characteristic face. It is the most common genetic cause of obesity and
Publikováno v:
British Journal of Haematology. 99:447-451
The white blood cell (WBC) count is correlated to the amount of body fat in humans, but the mechanism for this association is unknown. Leptin, a 16 kD protein produced in adipocytes, circulates in humans in direct proportion to the amount and percent
Autor:
Rudolph L. Leibel, Michael Rosenbaum, Jules Hirsch, Margery Nicolson, Ellen Murphy, Florence Chu
Publikováno v:
The Journal of Clinical Endocrinology & Metabolism. 82:3647-3654
Circulating concentrations of leptin are closely correlated with body fat mass, and may thus constitute an afferent limb of a system regulating body fatness, with efferent limbs that affect energy expenditure and food intake. We studied 50 subjects (
Autor:
Mary Ann Pelleymounter, Margery Nicolson, Olav A. Ormseth, Brian M. Barnes, Bert B. Boyer, Loren Buck
Publikováno v:
Comparative Biochemistry and Physiology Part C: Pharmacology, Toxicology and Endocrinology. 118:405-412
In mammals, leptin reduces energy intake and may increase energy expenditure as a means to maintain body weight and/or adiposity at an appropriate level. Hibernating mammals seasonally alter body mass, food intake, and body composition and, therefore
Autor:
Margery Nicolson, Kenneth J. Ellis
Publikováno v:
Pediatric Research. 42:484-488
Leptin, a hormone secreted by adipocytes, is elevated in blood of obese adults. It is unknown whether the concentration is affected by gender, ethnicity, age, or stage of sexual maturation in children. We measured serum leptin levels in 183 children