Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Margery E. Schuler"'
Publikováno v:
Journal of Medicinal Chemistry. 23:335-338
Twenty-five flavone-6-carboxylic acids were synthesized and tested as to their ability to inhibit histamine-induced gastric acid secretion in the rat. 3-Isopropoxy-4'-methoxyflavone-6-carboxylic acid (41) showed consistent oral activity while being d
Autor:
Marshall B. Wallach, Colin C. Beard, Michael Marx, Charles Alois Dvorak, Margery E. Schuler, Klaus K. Weinhardt, Patterson John W, Paul J. Wagner, S. H. Unger, A. P. Roszkowski
Publikováno v:
Journal of Medicinal Chemistry. 27:616-627
A series of 2-[( alkoxycarbonyl )amino]-4(5)-phenyl-2-imidazolines was prepared and evaluated for central nervous system (CNS) effects (antidepressant, anticonvulsant, muscle relaxant, and depressant) in animal models. Some separation of those CNS ac
Publikováno v:
Toxicology and Applied Pharmacology. 9:536-554
Doses of amphetamine were selected from the polyphasic mortality response curves for interaction studies with drugs representative of various pharmacologic groups that could be expected to interact with amphetamine. The results of these studies sugge
ChemInform Abstract: INHIBITION OF HISTAMINE-INDUCED GASTRIC SECRETION BY FLAVONE-6-CARBOXYLIC ACIDS
Publikováno v:
Chemischer Informationsdienst. 11
Twenty-five flavone-6-carboxylic acids were synthesized and tested as to their ability to inhibit histamine-induced gastric acid secretion in the rat. 3-Isopropoxy-4'-methoxyflavone-6-carboxylic acid (41) showed consistent oral activity while being d
Autor:
Charles Alois Dvorak, Marshall B. Wallach, Michael Marx, Margery E. Schuler, S. H. Unger, Colin C. Beard, A. P. Roszkowski, Paul J. Wagner, Patterson John W, Klaus K. Weinhardt
Publikováno v:
Chemischer Informationsdienst. 15
Ausgehend von den Diaminen (I) erhalt man uber die Verbindungen (III) bzw. (IV) die Imidazoline (V).
Publikováno v:
Journal of medicinal chemistry. 15(12)
Publikováno v:
Toxicology and applied pharmacology. 8(3)
Experiments were carried out in mice with intraperitoneal injections of dl-amphetamine at 10 dosages between 15 and 150 mg/kg. In animals kept in isolated conditions, it was observed that lethality follows a triphasic pattern, increasing between 15 a