Mitochondrial hyperfusion via metabolic sensing of regulatory amino acids.

Autor: Abdullah MO; Strathclyde Institute for Pharmacy and Biomedical Sciences, University of Strathclyde, Glasgow, Scotland., Zeng RX; Department of Biomedical and Medical Sciences, Queen's University, Kingston, Canada., Margerum CL; Department of Biomedical and Medical Sciences, Queen's University, Kingston, Canada., Papadopoli D; Lady Davis Institute, Gerald Bronfman Department of Oncology, Department of Biochemistry, Department of Experimental Medicine, McGill University, Montreal, Canada., Monnin C; Metabolomics Innovation Resource, Rosalind and Morris Goodman Cancer Institute, McGill University, Montreal, Canada., Punter KB; Department of Biomedical and Medical Sciences, Queen's University, Kingston, Canada., Chu C; Department of Biomedical and Medical Sciences, Queen's University, Kingston, Canada., Al-Rofaidi M; Strathclyde Institute for Pharmacy and Biomedical Sciences, University of Strathclyde, Glasgow, Scotland., Al-Tannak NF; Strathclyde Institute for Pharmacy and Biomedical Sciences, University of Strathclyde, Glasgow, Scotland; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Kuwait University, Kuwait City, Kuwait., Berardi D; Strathclyde Institute for Pharmacy and Biomedical Sciences, University of Strathclyde, Glasgow, Scotland., Rattray Z; Strathclyde Institute for Pharmacy and Biomedical Sciences, University of Strathclyde, Glasgow, Scotland., Rattray NJW; Strathclyde Institute for Pharmacy and Biomedical Sciences, University of Strathclyde, Glasgow, Scotland., Abraham SA; Department of Biomedical and Medical Sciences, Queen's University, Kingston, Canada., Eskelinen EL; Institute of Biomedicine, University of Turku, Turku, Finland., Watson DG; Strathclyde Institute for Pharmacy and Biomedical Sciences, University of Strathclyde, Glasgow, Scotland., Avizonis D; Metabolomics Innovation Resource, Rosalind and Morris Goodman Cancer Institute, McGill University, Montreal, Canada., Topisirovic I; Lady Davis Institute, Gerald Bronfman Department of Oncology, Department of Biochemistry, Department of Experimental Medicine, McGill University, Montreal, Canada., Chan EYW; Strathclyde Institute for Pharmacy and Biomedical Sciences, University of Strathclyde, Glasgow, Scotland; Department of Biomedical and Medical Sciences, Queen's University, Kingston, Canada. Electronic address: eywc@queensu.ca.

Publikováno v: Cell reports [Cell Rep] 2022 Aug 16; Vol. 40 (7), pp. 111198.