The nuclear receptor FXR inhibits Glucagon-Like Peptide-1 secretion in response to microbiota-derived Short-Chain Fatty Acids

Autor: Alexis Boulinguiez, Jean-Sébastien Annicotte, Laura Butruille, Anne Tailleux, Olivier Briand, Mohamed-Sami Trabelsi, Laure B. Bindels, Emilie Dorchies, Simon Peschard, Véronique Touche, Sandrine Caron, Emmanuelle Vallez, Sophie Lestavel, Sarah Ducastel, Steve Lancel, Oscar Chávez-Talavera, Nathalie M. Delzenne, Kadiombo Bantubungi, Bart Staels, Margaux Nawrot

Publikováno v: Scientific reports, Vol. 10, no.1, p. 174 [1-10] (2020)
Scientific Reports
Scientific Reports, 2020, 10 (1), pp.174. ⟨10.1038/s41598-019-56743-x⟩
Scientific Reports, Nature Publishing Group, 2020, 10 (1), pp.174. ⟨10.1038/s41598-019-56743-x⟩
Scientific Reports, Vol 10, Iss 1, Pp 1-10 (2020)

The gut microbiota participates in the control of energy homeostasis partly through fermentation of dietary fibers hence producing short-chain fatty acids (SCFAs), which in turn promote the secretion of the incretin Glucagon-Like Peptide-1 (GLP-1) by

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3827124755fcd285b435e83b8fd15554
https://hdl.handle.net/2078.1/227437