Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Margarita Salcedo-Magguilli"'
Autor:
Pierre-François Laterre, Stephan Witte, Jean-Marie Grouin, Simon Lambden, Bruno Francois, Sebastien Gibot, Marc Derive, Aurelie Olivier, Valerie Cuvier, Jean Jacques Garaud, Margarita Salcedo-Magguilli, Mitchell Levy
Publikováno v:
BMJ Open, Vol 11, Iss 7 (2021)
Introduction Septic shock is the subgroup of patients with sepsis, which presents as vasopressor dependence, an elevated blood lactate concentration and is associated with a mortality of at least 30%. Expression of the triggering receptor expressed o
Externí odkaz:
https://doaj.org/article/9b17e8be3e3443cebf020fb85a967645
Autor:
Bruno François, Simon Lambden, Tom Fivez, Sebastien Gibot, Marc Derive, Jean-Marie Grouin, Margarita Salcedo-Magguilli, Jérémie Lemarié, Nicolas De Schryver, Ville Jalkanen, Tarik Hicheur, Jean-Jacques Garaud, Valérie Cuvier, Ricard Ferrer, Morten Bestle, Ville Pettilä, Jean-Paul Mira, Camille Bouisse, Emmanuelle Mercier, Joris Vermassen, Vincent Huberlant, Isabelle Vinatier, Nadia Anguel, Mitchell Levy, Pierre-François Laterre, Pierre Asfar, Mai-Anh Nay, Christophe Guitton, Jean-Pierre Quenot, David Tran-Van, Julien Bohe, Gaëtan Plantefève, Saadalla Nseir, Jean-Yves Lefrant, Xavier Monnet, Laurent Papazian, Christophe Vinsonneau, Jean-Michel Constantin, Alexandre Mebazaa, Haikel Oueslati, Dolores Escudero, Fernando Martinez Sagasti, Enrique Piacentini, Paula Ramirez Galleymore, Thierry Dugernier, David Fagnoul, Isabelle Michaux, Allan Seibert, Matti Reinikainen, Thorbjørn Grøfte, Ignacio Martin-Loeches, John Laffey
Publikováno v:
The Lancet Respiratory Medicine.
Autor:
Bruno François, Simon Lambden, Jean-Jacques Garaud, Marc Derive, Jean-Marie Grouin, Pierre Asfar, Cédric Darreau, Jean-Paul Mira, Jean-Pierre Quenot, Jérémie Lemarié, Emmanuelle Mercier, Jean-Claude Lacherade, Christophe Vinsonneau, Tom Fivez, Julie Helms, Julio Badie, Mitchell Levy, Valérie Cuvier, Margarita Salcedo-Magguilli, Anne-Lise Laszlo-Pouvreau, Pierre-François Laterre, Sébastien Gibot
Publikováno v:
eClinicalMedicine. :102013
Autor:
Simon Lambden, Jean-Marie Grouin, Jean Jacques Garaud, Aurelie Olivier, Lucie Jolly, Marc Derive, Valerie Cuvier, Margarita Salcedo-Magguilli
Background:One of main new avenue of exploration in critical care medicine is the development of personalized medicine approaches to better determine which therapy provides the optimal risk/benefit ratio for subgroups of septic shock patients present
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c21560c02c97ba2608eb1e1a67452da7
https://doi.org/10.21203/rs.3.rs-1181242/v1
https://doi.org/10.21203/rs.3.rs-1181242/v1
Autor:
Jean-Jacques Garaud, Marc Derive, Xavier Wittebole, François Vandenhende, Thierry Dugernier, Valerie Cuvier, Peter Pickkers, Stephan Witte, Miguel Angel Gomez Sanchez, Margarita Salcedo-Magguilli, Aurelie Olivier, Bruno François, Jean-Paul Mira, Ricard Ferrer, Pierre-François Laterre, Sébastien Gibot
Publikováno v:
Intensive Care Medicine, 46, 7, pp. 1425-1437
Intensive Care Medicine, 46, 1425-1437
Intensive Care Medicine, 46, 1425-1437
Contains fulltext : 225478.pdf (Publisher’s version ) (Closed access) PURPOSE: Nangibotide is a specific TREM-1 inhibitor that tempered deleterious host-pathogens interactions, restored vascular function, and improved survival, in animal septic sho
Autor:
Marc Derive, Amir Boufenzer, Alexandre Mebazaa, Tom van der Poll, Margarita Salcedo-Magguilli, Pierre-François Laterre, Kevin Carrasco, Simon Lambden, Jean-Jacques Garaud, Lucie Jolly, Sébastien Gibot
Publikováno v:
Cellular & molecular immunology, 18(8), 2054-2056. Nature Publishing Group
Cellular and Molecular Immunology
Cellular & molecular immunology, Vol. 18, no.8, p. 2054-2056 (2021)
Cellular and Molecular Immunology
Cellular & molecular immunology, Vol. 18, no.8, p. 2054-2056 (2021)
TREM-1 (triggering receptor expressed on myeloid cells-1) is a transmembrane receptor expressed by innate immune cells, including endothelial cells and platelets. TREM-1 is a crucial mediator of septic shock that acts by synergizing with Toll-like re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4149c39f9c8310e9c6c579396365f4ad
https://pure.amc.nl/en/publications/strem1-is-a-specific-biomarker-of-trem1-pathway-activation(2935cc80-ded0-49e1-b672-d30af198a1be).html
https://pure.amc.nl/en/publications/strem1-is-a-specific-biomarker-of-trem1-pathway-activation(2935cc80-ded0-49e1-b672-d30af198a1be).html
Autor:
Simon Lambden, Pierre-François Laterre, Marc Derive, Bruno François, Margarita Salcedo-Magguilli, Sébastien Gibot, Aurelie Olivier, Valerie Cuvier, Mitchell M. Levy, Jean Jacques Garaud, Stephan Witte, Jean-Marie Grouin
Publikováno v:
BMJ Open
BMJ Open, Vol 11, Iss 7 (2021)
BMJ open, Vol. 11, no.7, p. e042921 [1-6] (2021)
BMJ Open, Vol 11, Iss 7 (2021)
BMJ open, Vol. 11, no.7, p. e042921 [1-6] (2021)
IntroductionSeptic shock is the subgroup of patients with sepsis, which presents as vasopressor dependence, an elevated blood lactate concentration and is associated with a mortality of at least 30%. Expression of the triggering receptor expressed on
Autor:
Jean-Jacques Garaud, Marc Derive, Margarita Salcedo-Magguilli, Lucie Jolly, Sebastien Gibot, David MOULIN
Publikováno v:
France, Patent n° : 20305604.9-1118. 2020
HAL
HAL
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::6a30df28e1bb55da4a174300dce9e76b
https://hal.archives-ouvertes.fr/hal-03005511
https://hal.archives-ouvertes.fr/hal-03005511
Autor:
Margarita Salcedo-Magguilli, Valerie Cuvier, Jean-Jacques Garaud, Ulrike Lorch, Stephan Witte, Aurelie Olivier, Isabelle Delor, Marc Derive, Sébastien Gibot
Publikováno v:
British Journal of Clinical Pharmacology. 84:2270-2279
Aims The peptide nangibotide is the first clinical-stage agent targeting the immunoreceptor TREM-1 (triggering receptor expressed on myeloid cells-1) and is being investigated as a novel therapy for acute inflammatory disorders such as septic shock.
Autor:
Valerie, Cuvier, Ulrike, Lorch, Stephan, Witte, Aurelie, Olivier, Sebastien, Gibot, Isabelle, Delor, Jean-Jacques, Garaud, Marc, Derive, Margarita, Salcedo-Magguilli
Publikováno v:
British journal of clinical pharmacology. 84(10)
AIMS: The peptide nangibotide is the first clinical‐stage agent targeting the immunoreceptor TREM‐1 (triggering receptor expressed on myeloid cells‐1) and is being investigated as a novel therapy for acute inflammatory disorders such as septic