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pro vyhledávání: '"Margarita Pérez-Casal"'
Autor:
Margarita Pérez-Casal, Colin Downey, Beatriz Cutillas-Moreno, Mirko Zuzel, Kenji Fukudome, Cheng Hock Toh
Publikováno v:
Haematologica, Vol 94, Iss 3 (2009)
Background The endothelial protein C receptor plays an important role within the protein C pathway in regulating coagulation and inflammation. Recently, we described that endothelial protein C receptor can be released in vitro in microparticulate for
Externí odkaz:
https://doaj.org/article/fc2fc715b8f146d9a7b7623aec77e098
Autor:
Mirko Zuzel, Cheng Hock Toh, Margarita Pérez-Casal, Beatriz Cutillas-Moreno, Colin Downey, Kenji Fukudome
Publikováno v:
Haematologica. 94:387-394
Background The endothelial protein C receptor plays an important role within the protein C pathway in regulating coagulation and inflammation. Recently, we described that endothelial protein C receptor can be released in vitro in microparticulate for
Publikováno v:
Blood. 105:1515-1522
Activated protein C (APC) treatment is now used for patients with severe sepsis. We investigated its effect in vitro on primary, physiologically relevant cells and demonstrate a novel mechanism of endothelial protein C receptor (EPCR) release that is
Autor:
Colin Downey, Margarita Pérez-Casal, Jecko Thachil, Ingeborg Welters, Duncan Wyncoll, Cheng Hock Toh, Victoria Thompson
Publikováno v:
Critical Care
Introduction Activated protein C (APC) induces release of microparticles (MP) from primary physiological cells, which are found in patients undergoing treatment with recombinant human APC (rhAPC) for severe sepsis. We hypothesised that APC on these c
Publikováno v:
Blood. 104:1923-1923
Activated protein C (APC) administration is now used for treating patients with severe sepsis. We investigated its effect on primary, physiologically relevant cells and demonstrate a novel mechanism of endothelial protein C receptor (EPCR) release fr
Publikováno v:
American Journal of Hematology. 48:140-140