Výsledky vyhledávání - "Margarita Pérez Martín"

Do changes in microglial status underlie neurogenesis impairments and depressive-like behaviours induced by psychological stress? A systematic review in animal models

Autor: Carmen Pedraza, Margarita Pérez-Martín, Patricia Chaves-Peña, Luis J. Santín, Andrea Nieto-Quero

Publikováno v: Neurobiology of Stress
Neurobiology of Stress, Vol 15, Iss, Pp 100356-(2021)
RIUMA. Repositorio Institucional de la Universidad de Málaga
instname

Stress may have a negative effect on mental health and is the primary environmental risk factor in the aetiology of depression. Nevertheless, the neurobiological mechanisms underlying this mood disorder remain poorly characterized. The hippocampus is

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b1aeb832b336f6cfe5a20131a82754a
https://pubmed.ncbi.nlm.nih.gov/34355047

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Effects of the LPA1 Receptor Deficiency and Stress on the Hippocampal LPA Species in Mice

Autor: Sara Tabbai, Román Dario Moreno-Fernández, Emma Zambrana-Infantes, Andrea Nieto-Quero, Jerold Chun, Maria García-Fernández, Guillermo Estivill-Torrús, Fernando Rodríguez de Fonseca, Luis Javier Santín, Tiago Gil Oliveira, Margarita Pérez-Martín, Carmen Pedraza

Publikováno v: Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
Frontiers in Molecular Neuroscience, Vol 12 (2019)

Lysophosphatidic acid (LPA) is an important bioactive lipid species that functions in intracellular signaling through six characterized G protein-coupled receptors (LPA1-6). Among these receptors, LPA1 is a strong candidate to mediate the central eff

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec556e0376090bab2203d50d1b50ea4f

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LPA1 receptor and chronic stress: Effects on behaviour and the genes involved in the hippocampal excitatory/inhibitory balance

Autor: Luis J. Santín, María García-Fernández, Guillermo Estivill-Torrús, Carmen Pedraza, Ana Luisa Gavito, Alexandre Bacq, F. Rodríguez de Fonseca, Olivia Zanoletti, Román D. Moreno-Fernández, Manuel Cifuentes, Carmen Sandi, Margarita Pérez-Martín, Cristina Rosell-Valle

Publikováno v: RIUMA. Repositorio Institucional de la Universidad de Málaga
instname

The LPA1 receptor, one of the six characterized G protein-coupled receptors (LPA1-6) through which lysophosphatidic acid acts, is likely involved in promoting normal emotional behaviours. Current data suggest that the LPA-LPA1-receptor pathway may be

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7ac52e86fc3fcf390f9c01389f666c8c
https://doi.org/10.1016/j.neuropharm.2019.107896

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Effects of the LPA

Autor: Sara, Tabbai, Román Dario, Moreno-Fernández, Emma, Zambrana-Infantes, Andrea, Nieto-Quero, Jerold, Chun, Maria, García-Fernández, Guillermo, Estivill-Torrús, Fernando, Rodríguez de Fonseca, Luis Javier, Santín, Tiago Gil, Oliveira, Margarita, Pérez-Martín, Carmen, Pedraza

Publikováno v: Frontiers in Molecular Neuroscience

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::c16cad9b8e5b08071591ccba1a29cc6d
https://pubmed.ncbi.nlm.nih.gov/31244601

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Effects of genetic deletion versus pharmacological blockade of the LPA1 receptor on depression-like behaviour and related brain functional activity

Autor: Francisco Javier Gómez-Salas, Guillermo Estivill-Torrús, Román D. Moreno-Fernández, Fernando Rodríguez de Fonseca, Andrea Nieto-Quero, Margarita Pérez-Martín, Luis J. Santín, Jerold Chun, Carmen Pedraza

Publikováno v: Disease Models & Mechanisms, Vol 11, Iss 9 (2018)

Animal models of psychopathology are particularly useful for studying the neurobiology of depression and characterising the subtypes. Recently, our group was the first to identify a possible relationship between the LPA1 receptor and a mixed anxiety-

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::08f129e1bff55df623af6a6869326f99
https://hdl.handle.net/10668/12776

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Effects of genetic deletion versus pharmacological blockade of the LPA

Autor: Román Darío, Moreno-Fernández, Andrea, Nieto-Quero, Francisco Javier, Gómez-Salas, Jerold, Chun, Guillermo, Estivill-Torrús, Fernando, Rodríguez de Fonseca, Luis Javier, Santín, Margarita, Pérez-Martín, Carmen, Pedraza

Publikováno v: Disease Models & Mechanisms

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::e8eb59691e8e5af89ce4c814bb6172c8
https://pubmed.ncbi.nlm.nih.gov/30061118

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Svct2 expression and function in reactive astrocytes is a common event in different brain pathologies

Autor: Antonio J. López-Gambero, Laura Trigueros, Ernesto R. Bongarzone, Margarita Pérez-Martín, Francisca Espinoza, Manuel Cifuentes, María José Oviedo, Francisco Nualart, Luciano Ferrada, Katterine Salazar, Romina Bertinat, Katherine Forman, Natalia Saldivia, Christian Bonansco, Fernando Martínez

Publikováno v: Molecular Neurobiology
Artículos CONICYT
CONICYT Chile
instacron:CONICYT

Ascorbic acid (AA), the reduced form of vitamin C, acts as a neuroprotector by eliminating free radicals in the brain. Sodium/vitamin C co-transporter isoform 2 (SVCT2) mediates uptake of AA by neurons. It has been reported that SVCT2 mRNA is induced

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f6967ec55d3d9422723015f3861d05d

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