Zobrazeno 1 - 10
of 86
pro vyhledávání: '"Margarita M. Ivanova"'
Autor:
Margarita M. Ivanova, Julia Dao, Neala Loynab, Sohailla Noor, Neil Kasaci, Andrew Friedman, Ozlem Goker-Alpan
Publikováno v:
Cells, Vol 13, Iss 8, p 716 (2024)
Background: Gaucher disease (GD) is caused by glucocerebrosidase (GCase) enzyme deficiency, leading to glycosylceramide (Gb-1) and glucosylsphingosine (Lyso-Gb-1) accumulation. The pathological hallmark for GD is an accumulation of large macrophages
Externí odkaz:
https://doaj.org/article/29e6db55d6a34a6ca779dba5aa3e06d8
Autor:
Margarita M. Ivanova, Julia Dao, Neil Kasaci, Andrew Friedman, Lauren Noll, Ozlem Goker-Alpan
Publikováno v:
Frontiers in Endocrinology, Vol 13 (2022)
Patients with Gaucher disease (GD) have progressive bone involvement that clinically presents with debilitating bone pain, structural bone changes, bone marrow infiltration (BMI), Erlenmeyer (EM) flask deformity, and osteoporosis. Pain is referred by
Externí odkaz:
https://doaj.org/article/6aba249aabef40e69053a53eed745fb7
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
Externí odkaz:
https://doaj.org/article/c15bae1665194b81803e850408bacf7d
Publikováno v:
Cells, Vol 12, Iss 16, p 2102 (2023)
Fabry disease (FD) is a lysosomal disorder caused by α-galactosidase A deficiency, resulting in the accumulation of globotriaosylceramide (Gb-3) and its metabolite globotriaosylsphingosine (Lyso-Gb-3). Cardiovascular complications and hypertrophic c
Externí odkaz:
https://doaj.org/article/6581602e81d745d0b37861167c52f2df
Autor:
Renuka Pudi Limgala, Vyacheslav Furtak, Margarita M. Ivanova, Erk Changsila, Floyd Wilks, Marie N. Fidelia‐Lambert, Ozlem Goker‐Alpan, Marjorie C. Gondré‐Lewis
Publikováno v:
JIMD Reports, Vol 59, Iss 1, Pp 60-68 (2021)
Abstract Population studies point to regional and ethnicity‐specific differences in genetic predisposition for some lysosomal storage disorders (LSDs). The aim of the study was to determine the prevalence of the three treatable forms of lysosomal s
Externí odkaz:
https://doaj.org/article/bceb67cff4b542f3b4942e0814047d2f
Autor:
Margarita M. Ivanova, Julia Dao, Neil Kasaci, Benjamin Adewale, Shaista Nazari, Lauren Noll, Jacqueline Fikry, Armaghan Hafez Sanati, Ozlem Goker-Alpan
Publikováno v:
PLoS ONE, Vol 16, Iss 10 (2021)
Gaucher disease (GD) is caused by deficiency of the lysosomal membrane enzyme glucocerebrosidase (GCase) and the subsequent accumulation of its substrate, glucosylceramide (GC). Mostly missense mutations of the glucocerebrosidase gene (GBA) cause GCa
Externí odkaz:
https://doaj.org/article/8ae526a440ac4cba991bf36e1ee47610
Autor:
Margarita M. Ivanova, Julia Dao, Neil Kasaci, Benjamin Adewale, Jacqueline Fikry, Ozlem Goker-Alpan
Publikováno v:
Biomolecules, Vol 10, Iss 6, p 837 (2020)
Enzyme replacement therapy (ERT) with recombinant alpha-galactosidase A (rh-α-Gal A) is the standard treatment for Fabry disease (FD). ERT has shown a significant impact on patients; however, there is still morbidity and mortality in FD, resulting i
Externí odkaz:
https://doaj.org/article/b547d2f486534fdd8cc4ee2b873aabf0
Autor:
Alexandra L. Martin, Sabra M. Abner, Margarita M. Ivanova, Yun Teng, Yoannis Imbert-Fernandez, Brandie N. Radde, Carolyn M. Klinge
PDF file - 189K
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::113575e8496feb5d8bd5ddf3a560ca19
https://doi.org/10.1158/1535-7163.22496892
https://doi.org/10.1158/1535-7163.22496892
Autor:
Alexandra L. Martin, Sabra M. Abner, Margarita M. Ivanova, Yun Teng, Yoannis Imbert-Fernandez, Brandie N. Radde, Carolyn M. Klinge
Mucin 1 (MUC1) is a diagnostic factor and therapy target in lung adenocarcinoma. MUC1 C-terminal intracellular domain (CD) interacts with estrogen receptor (ER) α and increases gene transcription in breast cancer cells. Because lung adenocarcinoma c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::503e2be490c50d75ce55993dc7100a7b
https://doi.org/10.1158/1535-7163.c.6535422
https://doi.org/10.1158/1535-7163.c.6535422
Autor:
Alexandra L. Martin, Sabra M. Abner, Margarita M. Ivanova, Yun Teng, Yoannis Imbert-Fernandez, Brandie N. Radde, Carolyn M. Klinge
PDF file - 59K
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0331a3f26aad96559606de3a5856dd8c
https://doi.org/10.1158/1535-7163.22496889
https://doi.org/10.1158/1535-7163.22496889