Zobrazeno 1 - 10
of 176
pro vyhledávání: '"Margarita L. Dubocovich"'
Autor:
Rosa Estrada-Reyes, Daniel B. Quero-Chávez, Salvador Alarcón-Elizalde, Montserrat G. Cercós, Citlali Trueta, Luis A. Constantino-Jonapa, Julián Oikawa-Sala, Jesús Argueta, Ricardo Cruz-Garduño, Margarita L. Dubocovich, Gloria A. Benítez-King
Publikováno v:
Molecules, Vol 27, Iss 17, p 5650 (2022)
Melatonin (MEL), an indolamine with diverse functions in the brain, has been shown to produce antidepressant-like effects, presumably through stimulating neurogenesis. We recently showed that the combination of MEL with ketamine (KET), an NMDA recept
Externí odkaz:
https://doaj.org/article/ead64480805d4e10a16d46e7bcb8bf55
Autor:
Susan L. Murphy, Elias M. Samuels, H. Robert Kolb, Linda S. Behar-Horenstein, Ellen Champagne, Christine Byks-Jazayeri, Jordan Hahn, Mary-Tara Roth, Fanny Ennever, Wajeeh Bajwa, Meher Singh, Gregory G. Homish, Margarita L. Dubocovich
Publikováno v:
Journal of Clinical and Translational Science, Vol 2, Pp 95-102 (2018)
IntroductionThe Best Practices in Social and Behavioral Research Course was developed to provide instruction on good clinical practice for social and behavioral trials. This study evaluated the new course.MethodsParticipants across 4 universities too
Externí odkaz:
https://doaj.org/article/15446780359e44d4bffb0db5a422668a
Autor:
Rosa Estrada-Reyes, Daniel B. Quero-Chávez, Citlali Trueta, Armida Miranda, Marcela Valdés-Tovar, Salvador Alarcón-Elizalde, Julián Oikawa-Sala, Jesús Argueta, Luis A. Constantino-Jonapa, Jesús Muñoz-Estrada, Margarita L. Dubocovich, Gloria Benítez-King
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 17, p 9225 (2021)
Major depressive disorder is a disabling disease with the number of affected individuals increasing each year. Current antidepressant treatments take between three to six weeks to be effective with forty percent of patients being resistant to treatme
Externí odkaz:
https://doaj.org/article/2dd225b839e742749eb19962ee9f2204
Autor:
Rosa Estrada-Reyes, Marcela Valdés-Tovar, Daniel Arrieta-Baez, Ana María Dorantes-Barrón, Daniel Quero-Chávez, Héctor Solís-Chagoyán, Jesús Argueta, Margarita L. Dubocovich, Gloria Benítez-King
Publikováno v:
International Journal of Molecular Sciences, Vol 19, Iss 8, p 2278 (2018)
Melatonin is synthesized by the pineal gland with a circadian rhythm in synchrony with the environmental light/dark cycle. A gradual increase in circulating levels of melatonin occur after lights off, reaching its maximum around the middle of the dar
Externí odkaz:
https://doaj.org/article/849929a636674c5b926e8a563883e1d0
Autor:
Susan L. Murphy, Elias M. Samuels, Christine Byks-Jazayeri, Ellen Champagne, Jordan Hahn, Brenda Eakin, Robert Kolb, Linda S. Behar-Horenstein, Susan Gardner, Fanny Ennever, Mary-Tara Roth, Margarita L. Dubocovich
Publikováno v:
Journal of Clinical and Translational Science, Vol 2, Pp 55-55 (2018)
OBJECTIVES/SPECIFIC AIMS: To evaluate the NIH-sponsored Best Practices for Social and Behavioral Research e-learning course. METHODS/STUDY POPULATION: Four universities partnered in a pilot study to evaluate this new course. Outcomes from 294 partici
Externí odkaz:
https://doaj.org/article/5b994b06404c4c468f42ad18f694dc42
Autor:
Susan Lynn Murphy, Christy Byks-Jazayeri, Brenda Eakin, Jordan Hahn, Brandon Lynn, Elias M. Samuels, Fanny Ennever, Sarah Peyre, Margarita L. Dubocovich, Wajeeh Bajwa
Publikováno v:
Journal of Clinical and Translational Science, Vol 1, Pp 45-45 (2017)
OBJECTIVES/SPECIFIC AIMS: To conduct a preliminary evaluation of the Social and Behavioral Research Best Practices Course. METHODS/STUDY POPULATION: Learners are sampled from 5 institutions: University of Michigan, University of Rochester, University
Externí odkaz:
https://doaj.org/article/d5776ac8f6ea4678a28ba821013195e3
Autor:
Darius Paul Zlotos, Gianluca Tosini, David Sugden, Nicolas Renault, Jesús Pintor, James Olcese, Regina Pekelmann Markus, Diana N. Krause, Ralf Jockers, Margarita L. Dubocovich, Philippe Delagrange, Daniel P. Cardinali
Publikováno v:
IUPHAR/BPS Guide to Pharmacology CITE. 2023
Melatonin receptors (nomenclature as agreed by the NC-IUPHAR Subcommittee on Melatonin Receptors [40]) are activated by the endogenous ligands melatonin and clinically used drugs like ramelteon, agomelatine and tasimelteon.
Publikováno v:
Methods Mol Biol
Melatonin ISBN: 9781071625927
Melatonin ISBN: 9781071625927
The neurohormone melatonin facilitates entrainment of biological rhythms to environmental light-dark conditions as well as phase-shifts of circadian rhythms in constant conditions via activation of the MT(1) and/or MT(2) receptors expressed within th
Autor:
Takaoki Kasahara, Margarita L. Dubocovich, Randall L. Hudson, Shigeharu Wakana, Tadafumi Kato, Ekue B Adamah-Biassi, Tamio Furuse, Kazuo Okanoya, Yui K. Matsumoto, Michele Sveinsson, Ikuo Miura, Shannon J. Clough, Chongyang Zhang, Anthony J Hutchinson
Publikováno v:
Journal of pineal researchREFERENCES. 71(2)
The hormone melatonin is synthesized from serotonin by two enzymatic reactions (AANAT and ASMT/HIOMT) in the pineal gland following a circadian rhythm with low levels during the day and high levels at night. The robust nightly peak of melatonin secre
Autor:
Margarita L. Dubocovich, Andrew Tsotinis, Jennie Lipinski, Aikaterini Sakellaropoulou, Jennifer Sosa, Vassiliki Tsakalidou, Ioannis Papanastasiou
Publikováno v:
The FASEB Journal. 35