Zobrazeno 1 - 10
of 97
pro vyhledávání: '"Margarita Hurtado"'
Autor:
Marwa Ben-Khemis, Dan Liu, Coralie Pintard, Zhuoyao Song, Margarita Hurtado-Nedelec, Jean-Claude Marie, Jamel El-Benna, Pham My-Chan Dang
Publikováno v:
Redox Biology, Vol 67, Iss , Pp 102898- (2023)
TNFα-mediated signaling pathways play a pivotal role in the pathogenesis of inflammatory diseases such as rheumatoid arthritis (RA) and inflammatory bowel disease (IBD) by promoting phagocyte inflammatory functions, notably cytokine release and reac
Externí odkaz:
https://doaj.org/article/94b0a40805df4d7483fa49cae9bf2e33
Innate immune deficiencies are associated with severity and poor prognosis in patients with COVID-19
Autor:
Marine Peyneau, Vanessa Granger, Paul-Henri Wicky, Dounia Khelifi-Touhami, Jean-François Timsit, François-Xavier Lescure, Yazdan Yazdanpanah, Alexy Tran-Dinh, Philippe Montravers, Renato C. Monteiro, Sylvie Chollet-Martin, Margarita Hurtado-Nedelec, Luc de Chaisemartin
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-11 (2022)
Abstract COVID-19 can cause acute respiratory distress syndrome, leading to death in many individuals. Evidence of a deleterious role of the innate immune system is accumulating, but the precise mechanisms involved remain unclear. In this study, we i
Externí odkaz:
https://doaj.org/article/e5b03108e84543adb56e5343235ab484
Publikováno v:
Journal of Venomous Animals and Toxins including Tropical Diseases, Vol 27 (2021)
Abstract Neutrophils play a pivotal role in innate immunity and in the inflammatory response. Neutrophils are very motile cells that are rapidly recruited to the inflammatory site as the body first line of defense. Their bactericidal activity is due
Externí odkaz:
https://doaj.org/article/75087b6ed0df42bcaaccf35c29a36319
Autor:
Rana M. Nassif, Elias Chalhoub, Pia Chedid, Margarita Hurtado-Nedelec, Elia Raya, Pham My-Chan Dang, Jean-Claude Marie, Jamel El-Benna
Publikováno v:
Biomedicines, Vol 10, Iss 2, p 319 (2022)
Metformin (1,1-dimethylbiguanide hydrochloride) is the most commonly used drug to treat type II diabetic patients. It is believed that this drug has several other beneficial effects, such as anti-inflammatory and anticancer effects. Here, we wanted t
Externí odkaz:
https://doaj.org/article/577b74ae5e04438e93147c3ac631c13a
Autor:
Min Liu, Samia Bedouhene, Margarita Hurtado-Nedelec, Coralie Pintard, Pham My-chan Dang, Shiyuan Yu, Jamel El-Benna
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Production of superoxide anion and other reactive oxygen species (ROS) by neutrophils has a vital role in host defense against microbes. However, over-production can induce cell injury participating to inflammation. Superoxide anion is produced by th
Externí odkaz:
https://doaj.org/article/134e7454f5f94008bd717ce242344c72
Publikováno v:
Cogent Engineering, Vol 4, Iss 1 (2017)
Previous studies have shown that the distribution of mean waiting times of different classes of customers is different for each class in a GI/G/1 queue with FIFO discipline. This experimental simulation study is motivated by those results as it inves
Externí odkaz:
https://doaj.org/article/aa5d9bca5d7041c3a0570112ee26e154
Autor:
Margarita Hurtado-Nedelec, Marie-José Csillag-Grange, Tarek Boussetta, Sahra Amel Belambri, Michèle Fay, Bruno Cassinat, Marie-Anne Gougerot-Pocidalo, Pham My-Chan Dang, Jamel El-Benna
Publikováno v:
Haematologica, Vol 98, Iss 10 (2013)
Myeloproliferative disorders are associated with increased risk of thrombosis and vascular complications. The pathogenesis of these complications is not completely known. Reactive oxygen species produced by the neutrophil NADPH oxidase could have a r
Externí odkaz:
https://doaj.org/article/4a805cf42005462c9f57a591f5ebe879
Autor:
Rodrigo de Oliveira Formiga, Flávia C. Amaral, Camila F. Souza, Daniel A. G. B. Mendes, Carlos W. S. Wanderley, Cristina B. Lorenzini, Adara A. Santos, Juliana Antônia, Lucas F. Faria, Caio C. Natale, Nicholas M. Paula, Priscila C. S. Silva, Fernanda R. Fonseca, Luan Aires, Nicoli Heck, Márick R. Starick, Celso M. Queiroz‐Junior, Felipe R. S. Santos, Filipe R. O. de Souza, Vivian V. Costa, Shana P. C. Barroso, Alexandre Morrot, Johan Van Weyenbergh, Regina Sordi, Frederico Alisson‐Silva, Fernando Q. Cunha, Edroaldo L. Rocha, Sylvie Chollet‐Martin, Maria Margarita Hurtado‐Nedelec, Clémence Martin, Pierre‐Régis Burgel, Daniel S. Mansur, Rosemeri Maurici, Matthew S. Macauley, André Báfica, Véronique Witko‐Sarsat, Fernando Spiller
Publikováno v:
British Journal of Pharmacology. 180:1460-1481
Neutrophil overstimulation plays a crucial role in tissue damage during severe infections. As pathogen-derived neuraminidase (NEU) stimulate neutrophils, we investigated whether host NEU can be targeted to regulate neutrophil dysregulation observed i
Autor:
Pedro Elí Sánchez Cabanillas, Ana Margarita Hurtado Alendes, Oscar Guillermo Valverde Sandoval, Hever Crisólogo Mucha Bonifacio
Publikováno v:
Horizontes. Revista de Investigación en Ciencias de la Educación. 7:229-238
La toma de decisiones organizacionales permite mejorar la gestión administrativa y pedagógica, ella se consolida a través de las relaciones sociales para así optimizar y dar solución a los problemas que se enfrenta en una organización. El objet
Autor:
Oscar Guillermo Valverde Sandoval, Ana Margarita Hurtado Alendes, Janet Carpio Mendoza, Pedro Elí Sánchez Cabanillas, Hever Crisólogo Mucha Bonifacio, Carlos Sixto Vega Vilca
Publikováno v:
Horizontes. Revista de Investigación en Ciencias de la Educación. 6:458-465
El aprendizaje significativo involucra poder retener una información, familiarizando los conceptos nuevos y permitiendo un cambio en la estructura que se tenía; generando nuevas soluciones a los problemas. En la actualidad debido a la pandemia del