Zobrazeno 1 - 10
of 60
pro vyhledávání: '"Margarita Dominguez-Villar"'
Publikováno v:
Pharmaceuticals, Vol 17, Iss 6, p 730 (2024)
With an estimated 10 million people infected, the deltaretrovirus human T-cell lymphotropic virus type 1 (HTLV-1) is the second most prevalent pathogenic retrovirus in humans after HIV-1. Like HIV-1, HTLV-1 overwhelmingly persists in a host via a res
Externí odkaz:
https://doaj.org/article/55e1d22dcbb648c08b626b82f1079631
Autor:
Allison K. Maher, Katie L. Burnham, Emma M. Jones, Michelle M. H. Tan, Rocel C. Saputil, Laury Baillon, Claudia Selck, Nicolas Giang, Rafael Argüello, Clio Pillay, Emma Thorley, Charlotte-Eve Short, Rachael Quinlan, Wendy S. Barclay, Nichola Cooper, Graham P. Taylor, Emma E. Davenport, Margarita Dominguez-Villar
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-17 (2022)
Although myeloid cell dysfunction has been observed in COVID-19, the underlying mechanisms remain incompletely understood. Here, the authors demonstrate that monocytes from patients with mild to moderate COVID-19 show a blunted innate immune response
Externí odkaz:
https://doaj.org/article/de001711bc5c459694d246aeb3195fa0
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Cellular metabolic remodeling is intrinsically linked to the development, activation, differentiation, function, and survival of T cells. T cells transition from a catabolic, naïve state to an anabolic effector state upon T cell activation. Subseque
Externí odkaz:
https://doaj.org/article/8802edc21a3c47f29ac9f3e302125377
Autor:
Amna Malik, Eszter N Tóth, Michelle S Teng, Jacob Hurst, Eleanor Watt, Lauren Wise, Natalie Kent, Jack Bartram, Louis Grandjean, Margarita Dominguez-Villar, Stuart Adams, Nichola Cooper
Publikováno v:
PLoS ONE, Vol 17, Iss 10, p e0274289 (2022)
While the majority of children infected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) display mild or no symptoms, rare individuals develop severe disease presenting with multisystem inflammatory syndrome (MIS-C). The reason for v
Externí odkaz:
https://doaj.org/article/3967135dd2e14b99b51011cd3b998cf0
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Regulatory T (Treg) cells are a heterogenous population of immunosuppressive T cells whose therapeutic potential for the treatment of autoimmune diseases and graft rejection is currently being explored. While clinical trial results thus far support t
Externí odkaz:
https://doaj.org/article/c20123422de1457eb5713a9aee9b25fa
Publikováno v:
Frontiers in Immunology, Vol 11 (2021)
Externí odkaz:
https://doaj.org/article/8a8b15324867447e931725c3d88c6e08
Publikováno v:
PLoS ONE, Vol 9, Iss 1, p e85191 (2014)
Adaptive T cell responses are critical for controlling HCV infection. While there is clinical evidence of a relevant role for regulatory T cells in chronic HCV-infected patients, based on their increased number and function; mechanisms underlying suc
Externí odkaz:
https://doaj.org/article/a6e968612c41473d853fd5bf6ea53a1b
Autor:
Kumar Subramanian, Saikat Paul, Andrew Libby, Jordan Patterson, Adam Arterbery, James Knight, Christopher Castaldi, Guilin Wang, Yaron Avitzur, Mercedes Martinez, Steve Lobritto, Yanhong Deng, Gan Geliang, Alexander Kroemer, Thomas Fishbein, Andrew Mason, Margarita Dominguez-Villar, Malaiyalam Mariappan, Udeme D. Ekong
Publikováno v:
The Journal of Immunology. 210:732-744
Regulatory T cells (Tregs) are not terminally differentiated but can acquire effector properties. Here we report an increased expression of human endogenous retrovirus 1 (HERV1-env) proteins in Tregs of patients with de novo autoimmune hepatitis and
Autor:
Margarita Dominguez-Villar
Publikováno v:
Nature Cell Biology.
Autor:
Caren Sourij, Faisal Aziz, Harald Kojzar, Anna M. Obermayer, Christoph Sternad, Alexander Müller, Norbert J. Tripolt, Peter N. Pferschy, Felix Aberer, Peter Schlenke, Barbara Kleinhappl, Martin Stradner, Nazanin Sareban, Martina Moritz, Margarita Dominguez‐Villar, Nick Oliver, Ivo Steinmetz, Harald Sourij
Publikováno v:
Diabetes, Obesity and Metabolism. 25:314-318