Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Margarita Camara"'
Autor:
Adem C. Koksal, Chelsea C. Boo, Margarita Camara, Lily Cheng, Nicholas Holoweckyj, Virginia N. Takahashi, Carolina S. Caceres, Andriani C. Patera, Antonio DiGiandomenico, Christopher Morehouse, Shonda Hawkins, Taylor S. Cohen, Melissa de los Reyes, Ashley E. Keller, Bret R. Sellman, Sonja Hess, Mark Pelletier, Ajitha Thanabalasuriar, Marcello Marelli, Abby J. Chiang, Aaron A Berlin
Publikováno v:
Science Advances. 7
The underlying mechanisms contributing to injury-induced infection susceptibility remain poorly understood. Here, we describe a rapid increase in neutrophil cell numbers in the lungs following induction of thermal injury. These neutrophils expressed
Autor:
Ajitha, Thanabalasuriar, Abby J, Chiang, Christopher, Morehouse, Margarita, Camara, Shonda, Hawkins, Ashley E, Keller, Adem C, Koksal, Carolina S, Caceres, Aaron A, Berlin, Nicholas, Holoweckyj, Virginia N, Takahashi, Lily, Cheng, Melissa, de Los Reyes, Mark, Pelletier, Andriani C, Patera, Bret, Sellman, Sonja, Hess, Marcello, Marelli, Chelsea C, Boo, Taylor S, Cohen, Antonio, DiGiandomenico
Publikováno v:
Science Advances
Neutrophils abandon infection control during wound repair.
The underlying mechanisms contributing to injury-induced infection susceptibility remain poorly understood. Here, we describe a rapid increase in neutrophil cell numbers in the lungs fol
The underlying mechanisms contributing to injury-induced infection susceptibility remain poorly understood. Here, we describe a rapid increase in neutrophil cell numbers in the lungs fol
Autor:
M. Margarita Camara, C. Kendall Stover, Wei Zhao, Joshua T. Thaden, Antonio DiGiandomenico, Linda G. Otterson, Norah J. Shire, Vance G. Fowler, Caitlin M. Guenther, Mike Huband, Paul Warrener, Ashley E. Keller
Publikováno v:
Journal of Infectious Diseases. 213:640-648
Background. The type 3 secretion protein PcrV and Psl exopolysaccharide are promising therapeutic antibody targets against Pseudomonas aeruginosa. We examined P. aeruginosa bloodstream infection (BSI) isolates for the ability to express PcrV and Psl
Publikováno v:
Case Studies in Construction Materials, Vol 18, Iss , Pp e02128- (2023)
San Cristóbal’s is a porous sandstone that is present in masonry structures of numerous historical buildings located in the southwest of Spain (15th–18th centuries). In order to guarantee conservation and structural integrity, most of these stru
Externí odkaz:
https://doaj.org/article/ae16b4b2b49648eb973bbba150ce7c4b
Autor:
Fabrizia Zatta, Maria Margarita Camara, Xiaodong Xiao, Elisabetta Cameroni, Davide Corti, Jessica Bonnell, Martina Beltramello, C. Kendall Stover, Antonio Lanzavecchia, JoAnn Suzich, Siro Bianchi, Meghan Pennini, Elena Semenova, Paul Warrener, Romana Cvitkovic, Anna De Marco, Wei Zhao, Mark Pelletier, Antonio DiGiandomenico, Qun Wang
Publikováno v:
Nature Communications
Nature Communications, Vol 8, Iss 1, Pp 1-12 (2017)
Nature Communications, Vol 8, Iss 1, Pp 1-12 (2017)
Emerging multidrug-resistant bacteria are a challenge for modern medicine, but how these pathogens are so successful is not fully understood. Robust antibacterial vaccines have prevented and reduced resistance suggesting a pivotal role for immunity i
Autor:
Ralph Minter, Ashley E. Keller, Vignesh Venkatraman, Michael P. McCarthy, Maria Margarita Camara, Sandrine Guillard, JoAnn Suzich, Lutz Jermutus, Peter Ravn, C. Kendall Stover, Qun Wang, Mladen Tomich, Paul Warrener, Jessica Bonnell, David Melnick, Jia Lin, Melissa Hamilton, Randall S. MacGill, Antonio DiGiandomenico
Publikováno v:
The Journal of Experimental Medicine
A human antibody facilitates opsonophagocytic killing, inhibits attachment of Pseudomonas aeruginosa, and exerts protective effects in several animal models of P. aeruginosa infection.
Pseudomonas aeruginosa is a leading cause of hospital-associ
Pseudomonas aeruginosa is a leading cause of hospital-associ
Autor:
Stan Mitelman, James Fleming, Bridget Finnerty, Maria Carolina Tuma, Paul Kussie, Asra Malikzay, Margarita Camara, David Surguladze, Eugene L. Piatnitski Chekler, Xiaohu Ouyang, James R. Tonra, Jacqueline Doody
Publikováno v:
Translational Oncology. 3(5):318-325
Microtubules are a well-validated target for anticancer therapy. Molecules that bind tubulin affect dynamic instability of microtubules causing mitotic arrest of proliferating cells, leading to cell death and tumor growth inhibition. Natural antitubu
Autor:
John Gooya, Sudha Swamynathan, Changshou Gao, Michael S. Kinch, Linda Xu, Margarita Camara, Damon L. Meyer, Steven Coats, Peter A. Kiener, Peter D. Senter, Ryan Fleming, Herren Wu, David A. Tice, Christine Fazenbaker, Krista Kinneer, Shenlan Mao, Dowdy Jackson
Publikováno v:
Cancer Research. 68:9367-9374
The EphA2 receptor tyrosine kinase is selectively expressed on the surface of many different human tumors. We have previously shown that tumor cells can be targeted by EphA2 monoclonal antibodies and that these antibodies function, in part, by induci
Autor:
Alexander S. Kiselyov, Jason Gerlak, Robin L. Rosler, Margarita Camara, James Fleming, Sui Ping Lee, Stan Mitelman, Asra Malikzay, Vatee Pattaropong, Ying Wang, Avdhoot Velankar, Evgueni L. Piatnitski, Leon M. Smith, Julia Winslow Lohman, Xiaoling Chen, Xiaohu Ouyang, David Surguladze, Joel Kawakami, M. Carolina Tuma, Marc Labelle, Jacqueline Doody, Hai-Ying He, Kai Zhou
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 16:1191-1196
Oxadiazole derivatives were synthesized and evaluated for their ability to inhibit tubulin polymerization and to cause mitotic arrest in tumor cells. The most potent compounds inhibited tubulin polymerization at concentrations below 1 microM. Lead an
Autor:
Jessica Bonnell, Li Peng, C. Kendall Stover, Maria Margarita Camara, Jingying Zha, Bret R. Sellman, Reena Varkey, Paul Warrener, Kimberly E. Cook, Antonio DiGiandomenico, Partha Chowdury
Publikováno v:
Antimicrobial agents and chemotherapy. 58(8)
Pseudomonas aeruginosa is a major cause of hospital-acquired infections, particularly in mechanically ventilated patients, and it is the leading cause of death in cystic fibrosis patients. A key virulence factor associated with disease severity is th