Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Margarita, Kirkova"'
Autor:
Stefani Vircheva, Rositsa Zamfirova, Almira Georgieva, Margarita Kirkova, Albena Alexandrova, Polina Mateeva, Elina Tzvetanova, Galina Nenkova
Publikováno v:
Cell Biochemistry and Function. 30:18-23
The pathogenesis of many diseases and different pathological conditions, including inflammation, is associated with excess production of reactive oxygen species (ROS). The present study aimed to investigate the effects of the antidepressant desiprami
Autor:
Elina Tzvetanova, Radoslav Girchev, Margarita Kirkova, Almira Georgieva, Albena Alexandrova, Galina Nenkova
Publikováno v:
Cell Biochemistry and Function. 29:135-141
The in vivo effects of nociceptin (N/OFQ(1-13)NH(2) ) and its structural analogues ([Dab(9) ]N/OFQ(1-13)NH(2) , [Dap(9) ]N/OFQ(1-13)NH(2) and [Cav(9) ]N/OFQ(1-13)NH(2) ) on the levels of lipid peroxidation and cell antioxidants (enzyme and non-enzyme
Autor:
Almira Pavlova, S. Todorov, Albena Alexandrova, Lubomir Petrov, Elina Tzvetanova, Rositsa Zamfirova, Margarita Kirkova
Publikováno v:
Open Medicine, Vol 5, Iss 1, Pp 123-131 (2010)
The production of reactive oxygen species (ROS) in cells is well balanced with their elimination by the antioxidant defence system. This balance is essential for maintenance of physiological conditions, and its disturbance (oxidative stress) has been
Autor:
Marta Kubera, Władysław Lasoń, Monika Leśkiewicz, Rositsa Zamfirova, Margarita Kirkova, S. Todorov
Publikováno v:
Pharmacological Reports. 61:1163-1172
The effect of side-chain shortening of N/OFQ(1-13)NH(2) at position 9 ([Orn(9)]N/OFQ(1-13)NH(2), [Dab(9)]N/OFQ(1-13)NH(2), [Dap(9)]N/OFQ(1-13)NH(2)) was studied regarding potential toxicity and antioxidant capacity. Staurosporine- and H2O2-induced da
Autor:
Albena Alexandrova, Lubomir Petrov, Galina Nenkova, Margarita Kirkova, Almira Pavlova, Elina Tzvetanova, Radoslav Girchev, Emilia Naydenova
Publikováno v:
Cell Biochemistry and Function. 27:243-250
In-vivo effects of nociceptin (N/OFQ(1-13)NH2) on the levels of lipid peroxidation and cell enzyme (superoxide dismutase, glutathione peroxidase and glutathione reductase) and non-enzyme (glutathione) antioxidants in brain of control and kainic acid-
Autor:
Elina Tzvetanova, Lubomir Petrov, Albena Alexandrova, S. Todorov, Margarita Kirkova, Polina Mateeva, Almira Pavlova, Rositsa Zamfirova
Publikováno v:
Open Life Sciences, Vol 4, Iss 2, Pp 170-178 (2009)
The effects of nociceptin(1–13)NH2 (N/OFQ(1–13)NH2) and its structural analogue [Orn9]N/OFQ(1–13)NH2 on acute carrageenan (CG)-induced peripheral inflammation and paw antioxidant status were studied. CG was injected intraplantarly in the right
Autor:
Almira Georgieva, Marián Kukan, Elina Tzvetanova, Mila Kessiova, Albena Alexandrova, Margarita Kirkova, Lubomir Petrov
Publikováno v:
Hepatology Research. 38:393-401
Aim: Previous studies have shown that proteasome inhibitors exerted protective effects against ischemia/reperfusion injury (IRI) of brain, heart, kidney and intestine. The aim of the present study was to investigate: (i) whether the proteasome inhibi
Publikováno v:
Cell Biochemistry and Function. 26:392-398
In vivo effects of N-benzyloxycarbonyl (Cbz)-Leu–Leu-leucinal (MG132) on chymotryptic-like (ChT-L), tryptic-like, and post-glutamyl peptide hydrolytic-like proteasome activities, protein oxidation, lipid peroxidation (LP), glutathione (GSH) level,
Publikováno v:
Acta Biologica Hungarica. 58:359-367
The in vitro effects of alloxan and the product of its reduction dialuric acid (alone or in combination with copper ions) on lipid peroxidation, carbonyl content, GSH level and antioxidant enzyme activities in rat liver and kidney have been studied.
Publikováno v:
Autonomic & Autacoid Pharmacology. 27:99-104
Summary 1 The in vivo effects of the non-steroid anti-inflammatory drug (NSAID) amtolmetin guacyl, a pro-drug of the NSAID tolmetin, on lipid peroxidation, glutathione levels and activity of antioxidant enzymes (superoxide dismutase, catalase, glutat