Výsledky vyhledávání - "Margarida Ressurreição"

Akademický článek

Identification of a non-exported Plasmepsin V substrate that functions in the parasitophorous vacuole of malaria parasites

Autor: Aline Fréville, Margarida Ressurreição, Christiaan van Ooij

Publikováno v: mBio, Vol 15, Iss 1 (2024)

ABSTRACTMalaria parasites alter multiple properties of the host erythrocyte by exporting proteins into the host cell. Many exported proteins contain a five-amino acid motif called the Plasmodium export element (PEXEL) that is cleaved by the parasite

Externí odkaz: https://doaj.org/article/42d4fced97374e76b7ebac8126bedc36

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Akademický článek

Use of a highly specific kinase inhibitor for rapid, simple and precise synchronization of Plasmodium falciparum and Plasmodium knowlesi asexual blood-stage parasites.

Autor: Margarida Ressurreição, James A Thomas, Stephanie D Nofal, Christian Flueck, Robert W Moon, David A Baker, Christiaan van Ooij

Publikováno v: PLoS ONE, Vol 15, Iss 7, p e0235798 (2020)

During the course of the asexual erythrocytic stage of development, Plasmodium spp. parasites undergo a series of morphological changes and induce alterations in the host cell. At the end of this stage, the parasites egress from the infected cell, af

Externí odkaz: https://doaj.org/article/80f4886ea7234c70a100a8f50abd34f2

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Akademický článek

Rapid Disruption of Dishevelled Activity Uncovers an Intercellular Role in Maintenance of Prickle in Core Planar Polarity Protein Complexes

Autor: Margarida Ressurreição, Samantha Warrington, David Strutt

Publikováno v: Cell Reports, Vol 25, Iss 6, Pp 1415-1424.e6 (2018)

Summary: Planar polarity, the coordinated polarization of cells in the plane of a tissue, is important for normal tissue development and function. Proteins of the core planar polarity pathway become asymmetrically localized at the junctions between c

Externí odkaz: https://doaj.org/article/77f9a03cb63943d78456c5905f7e75c7

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Akademický článek

Protein kinase C and extracellular signal-regulated kinase regulate movement, attachment, pairing and egg release in Schistosoma mansoni.

Autor: Margarida Ressurreição, Paulu De Saram, Ruth S Kirk, David Rollinson, Aidan M Emery, Nigel M Page, Angela J Davies, Anthony J Walker

Publikováno v: PLoS Neglected Tropical Diseases, Vol 8, Iss 6, p e2924 (2014)

Protein kinases C (PKCs) and extracellular signal-regulated kinases (ERKs) are evolutionary conserved cell signalling enzymes that coordinate cell function. Here we have employed biochemical approaches using 'smart' antibodies and functional screenin

Externí odkaz: https://doaj.org/article/5861865b3abe44c6ae317c14a78cac13

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Akademický článek

Functional mapping of protein kinase A reveals its importance in adult Schistosoma mansoni motor activity.

Autor: Paulu S R de Saram, Margarida Ressurreição, Angela J Davies, David Rollinson, Aidan M Emery, Anthony J Walker

Publikováno v: PLoS Neglected Tropical Diseases, Vol 7, Iss 1, p e1988 (2013)

Cyclic AMP (cAMP)-dependent protein kinase/protein kinase A (PKA) is the major transducer of cAMP signalling in eukaryotic cells. Here, using laser scanning confocal microscopy and 'smart' anti-phospho PKA antibodies that exclusively detect activated

Externí odkaz: https://doaj.org/article/b84af1e1bece4e5fb837f2da0b93fff0

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Identification of a non-exported Plasmepsin V substrate that functions in the parasitophorous vacuole of malaria parasites

Autor: Margarida Ressurreição, Aline Fréville, Christiaan van Ooij

Malaria parasites alter multiple properties of the host erythrocyte by exporting proteins into the host cell. Many exported proteins contain a five-amino acid motif called the Plasmodium Export Element (PEXEL) that is cleaved by the parasite protease

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::e1b807154e30d4b8219d4b4bae8636c2
https://doi.org/10.1101/2023.05.15.540838

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Synchronisation of Plasmodium falciparum and P. knowlesi In Vitro Cultures Using a Highly Specific Protein Kinase Inhibitor

Autor: Margarida, Ressurreição, Robert William, Moon, David Andrew, Baker, Christiaan, van Ooij

Publikováno v: Methods in molecular biology (Clifton, N.J.). 2470

Synchronisation of Plasmodium cultures is essential to investigate the complexities of time-dependent events associated with the asexual blood stage of the malaria parasite life cycle. Here we describe a procedure using ML10, a highly specific inhibi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::49badfb24c996f802ff6fc126511431c
https://pubmed.ncbi.nlm.nih.gov/35881342

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