Zobrazeno 1 - 10
of 48
pro vyhledávání: '"Margarida Duarte-Araújo"'
Autor:
Sofia Reis Brandão, Ana Reis-Mendes, Margarida Duarte-Araújo, Maria João Neuparth, Hugo Rocha, Félix Carvalho, Rita Ferreira, Vera Marisa Costa
Publikováno v:
Biomolecules, Vol 13, Iss 6, p 921 (2023)
Doxorubicin (DOX) and mitoxantrone (MTX) are classical chemotherapeutic agents used in cancer that induce similar clinical cardiotoxic effects, although it is not clear if they share similar underlying molecular mechanisms. We aimed to assess the eff
Externí odkaz:
https://doaj.org/article/665350ccb6244dc68ae15ac3f6f35d1e
Autor:
Sofia Reis Brandão, Ana Reis-Mendes, Margarida Duarte-Araújo, Maria João Neuparth, Félix Carvalho, Rita Ferreira, Vera Marisa Costa
Publikováno v:
RevSALUS, Vol 4, Iss Sup (2022)
Externí odkaz:
https://doaj.org/article/f2ae038b3b414331a37e4498f3176d42
Autor:
Marisa Esteves-Monteiro, Daniela Menezes-Pinto, Mariana Ferreira-Duarte, Patrícia Dias-Pereira, Manuela Morato, Margarida Duarte-Araújo
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 21, p 13233 (2022)
Diabetes mellitus (DM) is a chronic progressive metabolic disorder associated with several gastrointestinal complications, affecting up to 75% of patients. Knowing that Angiotensin II (AngII) also regulates intestinal contraction, we decided to evalu
Externí odkaz:
https://doaj.org/article/5dfad9e35b5a41528bd0ea8ca0e67a1b
Autor:
Ana Reis-Mendes, Ana Isabel Padrão, José Alberto Duarte, Salomé Gonçalves-Monteiro, Margarida Duarte-Araújo, Fernando Remião, Félix Carvalho, Emília Sousa, Maria Lourdes Bastos, Vera Marisa Costa
Publikováno v:
Biomolecules, Vol 11, Iss 11, p 1725 (2021)
Doxorubicin (DOX) is a topoisomerase II inhibitor commonly used in the treatment of several types of cancer. Despite its efficacy, DOX can potentially cause fatal adverse effects, like cardiotoxicity. This work aimed to assess the role of inflammatio
Externí odkaz:
https://doaj.org/article/ec9e2f7caa8e4a5d832370426ace8b2f
Autor:
Mariana Ferreira-Duarte, Tiago Rodrigues-Pinto, Teresa Sousa, Miguel A. Faria, Maria Sofia Rocha, Daniela Menezes-Pinto, Marisa Esteves-Monteiro, Fernando Magro, Patrícia Dias-Pereira, Margarida Duarte-Araújo, Manuela Morato
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 9, p 4836 (2021)
Angiotensin II (Ang II) regulates colon contraction, acting not only directly on smooth muscle but also indirectly, interfering with myenteric neuromodulation mediated by the activation of AT1 /AT2 receptors. In this article, we aimed to explore whic
Externí odkaz:
https://doaj.org/article/d539f98f70974ee9803df70713e5ddba
Autor:
Ana Reis-Mendes, José Luís Dores-Sousa, Ana Isabel Padrão, Margarida Duarte-Araújo, José Alberto Duarte, Vítor Seabra, Salomé Gonçalves-Monteiro, Fernando Remião, Félix Carvalho, Emília Sousa, Maria Lourdes Bastos, Vera Marisa Costa
Publikováno v:
Pharmaceuticals, Vol 14, Iss 6, p 510 (2021)
Mitoxantrone (MTX) is a pharmaceutical drug used in the treatment of several cancers and refractory multiple sclerosis (MS). Despite its therapeutic value, adverse effects may be severe, namely the frequently reported cardiotoxicity, whose mechanisms
Externí odkaz:
https://doaj.org/article/dcd80e51595a4a5ba63be05dcd0c6c2c
Autor:
Costa, Sofia Reis Brandão, Ana Reis-Mendes, Margarida Duarte Araújo, Maria João Neuparth, Hugo Rocha, Félix Carvalho, Rita Ferreira, Vera Marisa
Publikováno v:
Biomolecules; Volume 13; Issue 6; Pages: 921
Doxorubicin (DOX) and mitoxantrone (MTX) are classical chemotherapeutic agents used in cancer that induce similar clinical cardiotoxic effects, although it is not clear if they share similar underlying molecular mechanisms. We aimed to assess the eff
Autor:
Mariana Ferreira‐Duarte, Lilian Caroline Gonçalves Oliveira, Clara Quintas, Marisa Esteves‐Monteiro, Margarida Duarte‐Araújo, Teresa Sousa, Dulce Elena Casarini, Manuela Morato
Publikováno v:
Neurogastroenterology & Motility.
Autor:
Marisa Esteves-Monteiro, Mariana Ferreira-Duarte, Salomé Gonçalves-Monteiro, Sara Capas-Peneda, Fernando Magro, Tiago Rodrigues-Pinto, Margarida Duarte-Araújo, Manuela Morato, Patrícia Dias-Pereira, Daniela Menezes-Pinto
Publikováno v:
Experimental Animals. 70:245-256
Reproducibility in animal research is crucial for its reliance and translational relevance. The 2,4,6-trinitrobenzene sulfonic acid (TNBS)-induced model of inflammatory bowel disease (IBD) is widely used but inconsistently and incompletely characteri
Autor:
Margarida Duarte Araújo, Francisco Sampaio, Adelino F. Leite-Moreira, Ricardo Fontes-Carvalho, Ricardo Ladeiras-Lopes
Publikováno v:
Revista Portuguesa de Cardiologia, Vol 38, Iss 11, Pp 789-804 (2019)
Revista Portuguesa de Cardiologia (English Edition), Vol 38, Iss 11, Pp 789-804 (2019)
Revista Portuguesa de Cardiologia (English Edition), Vol 38, Iss 11, Pp 789-804 (2019)
Introduction: Diastolic dysfunction is highly prevalent and a key pathophysiological contributor to several cardiovascular diseases, especially heart failure with preserved ejection fraction. In addition, some evidence suggests diastolic dysfunction