Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Margaretha Jacobson"'
Autor:
Rosemary Jones, Kenneth S. Cohen, Margaretha Jacobson, David T. Scadden, Diane E. Capen, Dan G. Duda
Publikováno v:
Journal of Cellular and Molecular Medicine
The in vivo morphology and phenotype of circulating cells that spontaneously contribute to new vessel formation in adults remain unclear. Here, we use high-resolution imaging and flow cytometry to characterize the morphology and phenotype of a distin
Publikováno v:
Ultrastructural Pathology. 30:267-281
Smooth muscle cells are relatively rare cells in the microvessels of the normal adult lung but develop in high numbers in the clinical pulmonary hypertensions (PHs). Understanding this cellular response has profound implications for determining the p
Autor:
Carole Ho, Margaretha Jacobson, Pradeep G. Bhide, Jianhua Zhou, Miguel Medina, Kenneth S. Kosik, Tomohide Goto
Publikováno v:
The Journal of Comparative Neurology. 420:261-276
delta-catenin is a member of the Armadillo repeat family and component of the adherens junction discovered in a two-hybrid assay as a bona fide interactor with presenilin-1 (Zhou et al., [1997], NeuroReport 8:2085-2090), a protein which carries mutat
Publikováno v:
Cell and Tissue Research. 295:453-465
The present study analyzes smooth muscle myosin heavy chain (SMMHC) expression as lung microvascular precursor smooth muscle cells (PSMCs), cells derived from fibroblasts and intermediate cells (immature SMCs), acquire a smooth muscle phenotype in an
Publikováno v:
Cell and tissue research. 326(3)
Smooth muscle cells are mostly absent from the walls of microvessels in the adult lung but develop in large numbers as part of the pathology of human and experimental pulmonary hypertensions (PHs). We have previously shown, in an in vivo model of exp
Autor:
Hirosuke Kobayashi, Ryuji Hataishi, Tomoyuki Tomita, Warren M. Zapol, Margaretha Jacobson, Rosemary Jones, Hisashi Mitsufuji, Masumi Tanaka
Publikováno v:
American journal of respiratory cell and molecular biology. 24(4)
The objective of this study was to determine whether endogenous nitric oxide (NO), specifically the inducible NO synthase isoform (iNOS: NOS II), reduces or amplifies lung injury in mice breathing at a high oxygen tension. Previous studies have shown
Publikováno v:
American journal of respiratory cell and molecular biology. 20(4)
Little is known of the molecular basis of smooth-muscle cell development in the microvessels of the adult lung in pulmonary hypertension (PH). Using quantitative and immunogold electron microscopy techniques we report the development of microvascular
Publikováno v:
Cell and tissue research. 295(2)
Breathing air with a high oxygen tension induces an inflammatory response and injures the microvessels of the lung. The resulting development of smooth muscle cells in these segments contributes to changes in vasoreactivity and increased pulmonary ar
Autor:
Penelope P. Powell, Margaretha Jacobson, Kenneth E. Shepherd, Marcia Lipson, Rosemary Jones, Hirohisa Horinouchi, Chi-Chung Wang
Publikováno v:
American journal of respiratory cell and molecular biology. 19(4)
To characterize fibroblast growth factor (FGF) gene expression in the late fetal (days E18 to E22) and early postnatal lung (days P0 to P28), when the alveolar region undergoes extensive growth and reorganization, we analyzed the expression of four F
Publikováno v:
Neuroscience. 17:975-989
A monoclonal antibody (5F9) against microtubule-associated protein 2 is a selective and sensitive marker for neocortical dendrites in the mouse. The marker stains all dendrites. It affords a particularly comprehensive picture of the patterns of arran