Výsledky vyhledávání - "Margaretha E H Kaijen"

Akademický článek

Autologous Dendritic Cell Therapy in Mesothelioma Patients Enhances Frequencies of Peripheral CD4 T Cells Expressing HLA-DR, PD-1, or ICOS

Autor: Pauline L. de Goeje, Yarne Klaver, Margaretha E. H. Kaijen-Lambers, Anton W. Langerak, Heleen Vroman, André Kunert, Cor H. J. Lamers, Joachim G. J. V. Aerts, Reno Debets, Rudi W. Hendriks

Publikováno v: Frontiers in Immunology, Vol 9 (2018)

Introduction: Malignant pleural mesothelioma (MPM) is a malignancy with a very poor prognosis for which new treatment options are urgently needed. We have previously shown that dendritic cell (DC) immunotherapy provides a clinically feasible treatmen

Externí odkaz: https://doaj.org/article/36ed6879f3464311bdefb121712c1306

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Low-dose cyclophosphamide depletes circulating naïve and activated regulatory T cells in malignant pleural mesothelioma patients synergistically treated with dendritic cell-based immunotherapy

Autor: Henk C. Hoogsteden, Lisanne Noordam, Rudi W. Hendriks, Heleen Vroman, Koen Bezemer, Lex P.W.M. Maat, Joachim G.J.V. Aerts, Robin Cornelissen, Joost P.J.J. Hegmans, Margaretha E H Kaijen

Publikováno v: OncoImmunology, 7(12):e1474318. Landes Bioscience
Oncoimmunology
OncoImmunology, Vol 7, Iss 12 (2018)

Rationale: Regulatory T cells (Treg) play a pivotal role in the immunosuppressive tumor micro-environment in cancer, including mesothelioma. Recently, the combination of autologous tumor lysate-pulsed dendritic cells (DC) and metronomic cyclophospham

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a67cda43e7414dc8e754c6f77bcca4d
https://pure.eur.nl/en/publications/7d18c987-5296-457f-bcec-c56036fc8fbe

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