Zobrazeno 1 - 10
of 37
pro vyhledávání: '"Margarete Niebuhr"'
Publikováno v:
Allergy. 68:739-747
Background Interleukin-31 is a cytokine expressed by activated T cells. A major function of IL-31 in atopic dermatitis (AD) is the induction of pruritus in the skin. We recently showed that IL-31 induces pro-inflammatory cytokines following staphyloc
Autor:
Ralf Gutzmer, Imke Satzger, Uta Kuettler, Dirk Weinspach, Anika Mattern, Margarete Niebuhr, Alexander Kapp
Publikováno v:
Experimental Dermatology. 21:509-514
Overexpression of microRNA-21 (miR-21) has been observed in various cancer types, but little is known about the role of miR-21 in melanoma. In this study, we demonstrate that levels of miR-21 are significantly increased in primary melanoma tissues as
Autor:
Katja Wichmann, Thomas Werfel, Wolfgang Bäumer, Manfred Kietzmann, Margarete Niebuhr, Annice Heratizadeh
Publikováno v:
Experimental Dermatology. 21:52-56
The complement system has emerged as a bridge between innate and adaptive immune responses. An involvement of C3aR has been described during skin inflammation. The aim of the study was to investigate the role of C3a in a mouse model of allergic skin
Autor:
Thomas Werfel, S. Kasraie, Margarete Niebuhr, Oliver Dittrich-Breiholz, Michael Kracht, Verena Kopfnagel
Publikováno v:
Allergy. 67:41-49
To cite this article: Kasraie S, Niebuhr M, Kopfnagel V, Dittrich-Breiholz O, Kracht M, Werfel T. Macrophages from patients with atopic dermatitis show a reduced CXCL10 expression in response to staphylococcal α-toxin.Allergy 2012; 67: 41–49. Abst
Publikováno v:
Experimental Dermatology. 20:468-472
In many patients with atopic dermatitis (AD), the disease is complicated by their enhanced susceptibility to bacterial skin infections, especially with Staphylococcus aureus (S. aureus). Resistance to bacterial skin infections, e.g. S. aureus, is bas
Autor:
Hari Balaji, Annice Heratizadeh, Rudolf Valenta, Margarete Niebuhr, Thomas Werfel, Katja Wichmann, Irene Mittermann
Publikováno v:
British Journal of Dermatology. 164:316-324
Summary Background A subgroup of patients with atopic dermatitis (AD) produces IgE autoantibodies to human proteins which may be present in inflamed skin and perpetuate cutaneous inflammation. Objectives In order to investigate mechanisms of ‘autoa
Publikováno v:
Allergy. 66:845-852
To cite this article: Kasraie S, Niebuhr M, Baumert K, Werfel T. Functional effects of Interleukin 31 in human primary keratinocytes. Allergy 2011; 66: 845–852. Abstract Background: Interleukin (IL)-31 is a T-cell cytokine acting through a heterodi
Staphylococcal α-Toxin Induces a Higher T Cell Proliferation and Interleukin-31 in Atopic Dermatitis
Publikováno v:
International Archives of Allergy and Immunology. 156:412-415
Background: Patients with atopic dermatitis (AD) are frequently colonized with α-toxin-producing Staphylococcus aureus which is in turn positively correlated with the severity of eczema. Methods: In this study we addressed T cell proliferation and T
Publikováno v:
Experimental Dermatology. 19:873-877
The human epidermis provides a first line of defense against exogenous pathogens. Resistance to bacterial skin infections, e.g. with Staphylococcus aureus (S. aureus), is based on the function of intact innate immune mechanisms in the epidermis, main
Publikováno v:
Experimental Dermatology. 17:1052-1056
Chronic skin ulcers, such as leg ulcers, pressure sores and diabetic foot ulcers, are a challenge to physicians and medical personnel and a cause of tremendous discomfort and ensuing loss of quality of life to the patients. Wound healing involves pro