Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Margarete M Karg"'
Autor:
Margarete M. Karg, May Moorefield, Emma Hoffmann, Hannah Philipose, Drenushe Krasniqi, Cindy Hoppe, Daisy Y. Shu, Shintaro Shirahama, Bruce R. Ksander, Magali Saint-Geniez
Publikováno v:
Immunity & Ageing, Vol 20, Iss 1, Pp 1-14 (2023)
Abstract Background Increased age is a risk factor for the development and progression of retinal diseases including age-related macular degeneration (AMD). Understanding the changes that occur in the eye due to aging is important in enhancing our un
Externí odkaz:
https://doaj.org/article/c95cd76dd86c4d5198c16417aa0be33a
Autor:
Margarete M. Karg, May Moorefield, Emma Hoffmann, Hannah Philipose, Drenushe Krasniqi, Cindy Hoppe, Daisy Y. Shu, Shintaro Shirahama, Bruce R. Ksander, Magali Saint-Geniez
Publikováno v:
Immunity & Ageing, Vol 20, Iss 1, Pp 1-1 (2023)
Externí odkaz:
https://doaj.org/article/5ac7dca8046f4015b09628d2d9dcaf67
Autor:
Daisy Y. Shu, Scott I. Frank, Tessa C. Fitch, Margarete M. Karg, Erik R. Butcher, Emmanuella Nnuji-John, Leo A. Kim, Magali Saint-Geniez
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 15 (2022)
The retinal pigment epithelium (RPE) acts as a metabolic gatekeeper between photoreceptors and the choroidal vasculature to maintain retinal function. RPE dysfunction is a key feature of age-related macular degeneration (AMD), the leading cause of bl
Externí odkaz:
https://doaj.org/article/3648d0b4c0e048b698aee8e295c6130e
Autor:
Andreas Mackensen, Hannah Reimann, Edith D van der Meijden, Judith Bausenwein, Sascha Kretschmann, Anna Luise Bernhardt, Julia Zeun, Miriam Marecek, Margarete M Karg, Tabea Haug, Lisa Meintker, Gloria Lutzny-Geier, Anita N Kremer
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss 7 (2021)
Background Graft-versus-host-disease (GvHD) is a major problem in allogeneic stem cell transplantation. We previously described two types of endogenous human leukocyte antigen (HLA)-II restricted antigens depending on their behavior towards HLA-DM. W
Externí odkaz:
https://doaj.org/article/bcc0d925c21d4c1b89cc3f57512617d1
Autor:
Jacobus J. Bosch, Andreas Mackensen, Ludwig M. Heindl, Bruce R. Ksander, Yazid J. Resheq, Barbara Bock, Jonas Sommer, Tanja Rottmar, Christian Buettner, Nasrin Refaian, Lukas John, Margarete M. Karg
Supplementary Figure from Midkine Promotes Metastasis and Therapeutic Resistance via mTOR/RPS6 in Uveal Melanoma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ecba16dd55d3db99a9f40d6f105798f
https://doi.org/10.1158/1541-7786.22528151.v1
https://doi.org/10.1158/1541-7786.22528151.v1
Autor:
Jacobus J. Bosch, Andreas Mackensen, Ludwig M. Heindl, Bruce R. Ksander, Yazid J. Resheq, Barbara Bock, Jonas Sommer, Tanja Rottmar, Christian Buettner, Nasrin Refaian, Lukas John, Margarete M. Karg
Uveal melanoma is a rare form of melanoma that originates in the eye, exerts widespread therapeutic resistance, and displays an inherent propensity for hepatic metastases. Because metastatic disease is characterized by poor survival, there is an unme
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::529f4cf8087ec86f8e4438a18161bb2f
https://doi.org/10.1158/1541-7786.c.6545630.v1
https://doi.org/10.1158/1541-7786.c.6545630.v1
Autor:
Daisy Y. Shu, Scott I. Frank, Margarete M. Karg, Erik R. Butcher, Emmanuella Nnuji‐John, Rishi Shah, Deviprasad Gollapalli, Magali Saint‐Geniez
Publikováno v:
The FASEB Journal. 36
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::175c28b7b58f363e62d0116821bdd86b
https://doi.org/10.1096/fasebj.2022.36.s1.0r785
https://doi.org/10.1096/fasebj.2022.36.s1.0r785
Autor:
Margarete M. Karg, May Moorefield, Emma Hoffmann, Daisy Shu, Drenushe Krasniqi, Hannah Philipose, Bruce R. Ksander, Magali Saint‐Geniez
Publikováno v:
The FASEB Journal. 36
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fd72422fcbfd48f87fe28a1d284b7f04
https://doi.org/10.1096/fasebj.2022.36.s1.r5839
https://doi.org/10.1096/fasebj.2022.36.s1.r5839
Autor:
Bruce R. Ksander, Morgan E. Levine, Emma Hoffmann, Luis A. Rajman, Zhigang He, Meredith S Gregory-Ksander, Michael Bonkowski, Anitha Krishnan, Jae-Hyun Yang, Chen Wang, Alice E. Kane, Ekaterina Korobkina, Songlin Zhou, Xiao Tian, Margarita Meer, George M. Church, Yu D, Michael B. Schultz, Karolina Chwalek, Noah Davidsohn, Steve Horvath, Yuancheng Lu, Qiurui Zeng, Konrad Hochedlinger, David A. Sinclair, Daniel L. Vera, Vadim N. Gladyshev, Margarete M. Karg, Benedikt Brommer
Publikováno v:
Nature
Ageing is a degenerative process that leads to tissue dysfunction and death. A proposed cause of ageing is the accumulation of epigenetic noise that disrupts gene expression patterns, leading to decreases in tissue function and regenerative capacity1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e889826298203f3bbb26dfda61779a3
https://doi.org/10.1038/s41586-020-2975-4
https://doi.org/10.1038/s41586-020-2975-4
Autor:
Margarete M Karg, Barbara Bock, Ludwig M. Heindl, Jonas Sommer, Anika Fischer, Jacobus J. Bosch, Imke Atreya, Sabine Britting, Andreas Mackensen, Julia M Kittler
Publikováno v:
Oncotarget
Uveal melanoma is the most common primary malignancy of the eye in adults. Despite significant improvements in treatment of the primary tumor, to date none of these therapies prevent metastatic disease or improve overall survival. We are exploring im
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::218aa05e2789003ce4438e8ad78ae2fe
http://europepmc.org/articles/PMC6442993
http://europepmc.org/articles/PMC6442993