Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Margareta Porsmyr Palmertz"'
Autor:
Serge Ducommun, Paulo R. Jannig, Igor Cervenka, Marta Murgia, Melanie J. Mittenbühler, Ekaterina Chernogubova, José M. Dias, Baptiste Jude, Jorge C. Correia, Jonathan G. Van Vranken, Gabriel Ocana-Santero, Margareta Porsmyr-Palmertz, Sarah McCann Haworth, Vicente Martínez-Redondo, Zhengye Liu, Mattias Carlström, Matthias Mann, Johanna T. Lanner, Ana I. Teixeira, Lars Maegdefessel, Bruce M. Spiegelman, Jorge L. Ruas
Publikováno v:
Molecular Metabolism, Vol 82, Iss , Pp 101912- (2024)
Objective: Skeletal muscle plasticity and remodeling are critical for adapting tissue function to use, disuse, and regeneration. The aim of this study was to identify genes and molecular pathways that regulate the transition from atrophy to compensat
Externí odkaz:
https://doaj.org/article/2abd30b26178418fbe5ccf30fb438f44
Autor:
Duarte M. S. Ferreira, Arthur J. Cheng, Leandro Z. Agudelo, Igor Cervenka, Thomas Chaillou, Jorge C. Correia, Margareta Porsmyr-Palmertz, Manizheh Izadi, Alicia Hansson, Vicente Martínez-Redondo, Paula Valente-Silva, Amanda T. Pettersson-Klein, Jennifer L. Estall, Matthew M. Robinson, K. Sreekumaran Nair, Johanna T. Lanner, Jorge L. Ruas
Publikováno v:
Skeletal Muscle, Vol 9, Iss 1, Pp 1-19 (2019)
Abstract Background Skeletal muscle mass and strength are crucial determinants of health. Muscle mass loss is associated with weakness, fatigue, and insulin resistance. In fact, it is predicted that controlling muscle atrophy can reduce morbidity and
Externí odkaz:
https://doaj.org/article/2f827301045e4b2e8bc503169f19361b
Autor:
Jorge C. Correia, Julie Massart, Jan Freark de Boer, Margareta Porsmyr-Palmertz, Vicente Martínez-Redondo, Leandro Z. Agudelo, Indranil Sinha, David Meierhofer, Vera Ribeiro, Marie Björnholm, Sascha Sauer, Karin Dahlman-Wright, Juleen R. Zierath, Albert K. Groen, Jorge L. Ruas
Publikováno v:
Molecular Metabolism, Vol 4, Iss 12, Pp 891-902 (2015)
Objective: Farnesoid X receptor (FXR) plays a prominent role in hepatic lipid metabolism. The FXR gene encodes four proteins with structural differences suggestive of discrete biological functions about which little is known. Methods: We expressed ea
Externí odkaz:
https://doaj.org/article/8ebda816bd19486b9e767bdbd21f6a38
Autor:
Mark R. Southern, M. Otrocka, Ulf Martens, Vicente Martínez-Redondo, Igor Cervenka, Bo Lundgren, Jorge C. Correia, Amanda T. Pettersson-Klein, Daniel Ferreira, Patrick R. Griffin, Theodore M. Kamenecka, A. Jenmalm-Jensen, Manizheh Izadi, Michael D. Cameron, Leandro Z. Agudelo, Jorge L. Ruas, Margareta Porsmyr-Palmertz
Publikováno v:
Molecular Metabolism
Molecular Metabolism, Vol 9, Iss, Pp 28-42 (2018)
Molecular Metabolism, Vol 9, Iss, Pp 28-42 (2018)
Objective The peroxisome proliferator-activated receptor-γ coactivator-1α1 (PGC-1α1) regulates genes involved in energy metabolism. Increasing adipose tissue energy expenditure through PGC-1α1 activation is potentially beneficial for systemic met
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c8adef5e0e4e4795105a62227894df6c
https://doi.org/10.1016/j.molmet.2018.01.017
https://doi.org/10.1016/j.molmet.2018.01.017
Autor:
Jorge C. Correia, Margareta Porsmyr-Palmertz, Jennifer L. Estall, Paula Valente-Silva, Leandro Z. Agudelo, Thomas Chaillou, Arthur J. Cheng, Jorge L. Ruas, Johanna T. Lanner, K. Sreekumaran Nair, Igor Cervenka, Duarte M. S. Ferreira, Vicente Martínez-Redondo, Manizheh Izadi, Alicia Hansson, Matthew M. Robinson, Amanda T. Pettersson-Klein
Publikováno v:
Skeletal Muscle
Skeletal Muscle, Vol 9, Iss 1, Pp 1-19 (2019)
Skeletal Muscle, Vol 9, Iss 1, Pp 1-19 (2019)
Background Skeletal muscle mass and strength are crucial determinants of health. Muscle mass loss is associated with weakness, fatigue, and insulin resistance. In fact, it is predicted that controlling muscle atrophy can reduce morbidity and mortalit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f16847300244e4f51c54010b19e97c7c
https://pubmed.ncbi.nlm.nih.gov/31666122
https://pubmed.ncbi.nlm.nih.gov/31666122
Autor:
Louise Sivertsson, Etienne P. A. Neve, Margareta Porsmyr Palmertz, Magnus Ingelman-Sundberg, Irene Edebert
Publikováno v:
Molecular Pharmacology. 83:659-670
We have previously shown that confluent growth of the human hepatoma cell line Huh7 substantially induces the CYP3A4 mRNA, protein, and activity levels. Here, the mechanisms behind were investigated, and a transcriptome analysis revealed significant
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::75a973116f6e7599fb27f9c3a0690a73
https://doi.org/10.1124/mol.112.082305
https://doi.org/10.1124/mol.112.082305
Autor:
Amanda T. Pettersson-Klein, Zachary Gerhart-Hines, Per Olof Berggren, Per Magne Ueland, Galyna Bryzgalova, Jorge L. Ruas, Teresa Pereira, Elahu G. Sustarsic, Petter Brodin, Margareta Porsmyr-Palmertz, Jorge C. Correia, Vicente Martínez-Redondo, Igor Cervenka, Leandro Z. Agudelo, Tadepally Lakshmikanth, Manizheh Izadi, Duarte M. S. Ferreira, Øivind Midttun, Paulo R. Jannig, Shamim Dadvar
Publikováno v:
Cell Metabolism. 27:378-392.e5
Summary The role of tryptophan-kynurenine metabolism in psychiatric disease is well established, but remains less explored in peripheral tissues. Exercise training activates kynurenine biotransformation in skeletal muscle, which protects from neuroin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::108407731483e3fc547a4aed55f4af1b
https://doi.org/10.1016/j.cmet.2018.01.004
https://doi.org/10.1016/j.cmet.2018.01.004
Autor:
Jorge L. Ruas, Jorge C. Correia, Julie Massart, Vera Ribeiro, Albert K. Groen, Margareta Porsmyr-Palmertz, Leandro Z. Agudelo, Juleen R. Zierath, Marie Björnholm, Karin Dahlman-Wright, Sascha Sauer, Indranil Sinha, Vicente Martínez-Redondo, Jan Freark de Boer, David Meierhofer
Publikováno v:
Current drug metabolism, 4(12), 891-902
Molecular Metabolism
Molecular Metabolism, Vol 4, Iss 12, Pp 891-902 (2015)
Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
Molecular Metabolism
Molecular Metabolism, Vol 4, Iss 12, Pp 891-902 (2015)
Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
Objective Farnesoid X receptor (FXR) plays a prominent role in hepatic lipid metabolism. The FXR gene encodes four proteins with structural differences suggestive of discrete biological functions about which little is known. Methods We expressed each
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ee1f4c02be0cf74bbc43590b189775f
https://research.rug.nl/en/publications/f77ec073-814b-4aca-995e-6df20e427e15
https://research.rug.nl/en/publications/f77ec073-814b-4aca-995e-6df20e427e15
Autor:
Margareta Porsmyr-Palmertz, Katalin Monostory, Viola Tamási, Eszter Hazai, Magnus Ingelman-Sundberg, László Vereczkey
Publikováno v:
Drug Metabolism and Disposition. 31:1310-1314
CYP2E1-inducing capacity of xenobiotics was determined in cultured hepatocytes on the basis of enzyme activities (chlorzoxazone 6-hydroxylation and 7-ethoxycoumarin O-dealkylation) and protein levels. Hepatocytes in culture showed rapid loss of CYP2E
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::32f31cf494b850262e1c35638366926f
https://doi.org/10.1124/dmd.31.11.1310
https://doi.org/10.1124/dmd.31.11.1310
Autor:
Anna Hjertén, Margareta Porsmyr-Palmertz, Anastasia Simi, Magnus Ingelman-Sundberg, Niclas Tindberg
Publikováno v:
Journal of Neurochemistry. 83:727-737
Chlomethiazole and pyridinyl imidazole compounds, exemplified by SB203580, are structurally distinct p38 mitogen-activated protein kinase inhibitors with neuroprotective properties in models of cerebral ischaemia. We have examined their effects in in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::62b30f894a96ea51892ae97bb5caaca7
https://doi.org/10.1046/j.1471-4159.2002.01178.x
https://doi.org/10.1046/j.1471-4159.2002.01178.x