Identification of four novel genes contributing to familial elevated plasma HDL cholesterol in humans

Autor: Michael Winther, Chris Radomski, Linus S. Lin, Patrick Franchini, G. Kees Hovingh, Karen O. Akinsanya, Maryanne Mattice, Michael R. Hayden, Robin Sherrington, Margaret vanHeek, Annick Legendre, Ioannis M. Stylianou, Roshni R. Singaraja, Brian K. Hubbard, Liangsu Wang, John J.P. Kastelein, Andrew S. Plump, Lyndon J. Mitnaul, Kenny K. Wong, Ian Tietjen

Publikováno v: Journal of lipid research, 55(8), 1693-1701. American Society for Biochemistry and Molecular Biology Inc.
Journal of Lipid Research, Vol 55, Iss 8, Pp 1693-1701 (2014)

While genetic determinants strongly influence HDL cholesterol (HDLc) levels, most genetic causes underlying variation in HDLc remain unknown. We aimed to identify novel rare mutations with large effects in candidate genes contributing to extreme HDLc

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::419aaded4b36fbcb1f6d771e259951ba
https://pure.amc.nl/en/publications/identification-of-four-novel-genes-contributing-to-familial-elevated-plasma-hdl-cholesterol-in-humans(38861fa3-1018-4696-a5f6-6ef8c28fa8eb).html