Zobrazeno 1 - 10
of 59
pro vyhledávání: '"Margaret Werner-Washburne"'
Publikováno v:
PLoS ONE, Vol 4, Iss 11, p e7813 (2009)
Computational prediction of protein interactions typically use protein domains as classifier features because they capture conserved information of interaction surfaces. However, approaches relying on domains as features cannot be applied to proteins
Externí odkaz:
https://doaj.org/article/32ae278e21d94a6ea78d041dfbf6895d
The proteomics of quiescent and nonquiescent cell differentiation in yeast stationary-phase cultures
Autor:
Osorio Meirelles, Larry A. Sklar, Anne E. Dodson, Elaine Manzanilla, Ray M. Joe, Margaret Werner-Washburne, Phillip H. Tapia, Melissa Wilson, Sushmita Roy, Bruce S. Edwards, Mark B. Carter, Swagata Chakraborty, George S. Davidson, Susan Young, Chris Allen
Publikováno v:
Molecular Biology of the Cell
Starved yeast cultures differentiate into quiescent (Q) and nonquiescent (NQ) cell fractions. The yeast GFP-fusion library (4159 strains) and high-throughput flow cytometry were used to study this process. This showed significant metabolic and physio
Autor:
Margaret Werner-Washburne
Publikováno v:
CBE Life Sciences Education
This essay elucidates four universal principles that have been used in a psychosocial mentoring approach to help mentors and mentees to understand themselves, learn productive reframing, build their personal and family narratives, discover their path
Publikováno v:
IET Systems Biology. 3:404-413
Cellular networks inferred from condition-specific microarray data can capture the functional rewiring of cells in response to different environmental conditions. Unfortunately, many algorithms for inferring cellular networks do not scale to whole-ge
Publikováno v:
Molecular Biology of the Cell. 20:3851-3864
Ssd1 is an RNA-binding protein that affects literally hundreds of different processes and is polymorphic in both wild and lab yeast strains. We have used transcript microarrays to compare mRNA levels in an isogenic pair of mutant (ssd1-d) and wild-ty
Autor:
Thomas Brettin, B. Gillian Turgeon, Jette Thykaer, Steven P. Briggs, Tamas Torok, A. Diego Martinez, Christopher W. Schadt, Joan W. Bennett, William S. Adney, Margaret Werner-Washburne, Joseph Heitman, Gerald A. Tuskan, Fred J. Brockman, John W. Taylor, R. Michael Miller, Michael E. Himmel, Scott E. Baker, Patrik D'haeseleer, Randy M. Berka, Daniel S. Rokhsar
Publikováno v:
Fungal Biology Reviews. 22:1-5
To date, the number of ongoing filamentous fungal genome sequencing projects is almost tenfold fewer than those of bacterial and archaeal genome projects. The fungi chosen for sequencing represent narrow kingdom diversity; most are pathogens or model
Autor:
Zhu Chen, Helen K. Baca, Susan M. Brozik, Eric C. Carnes, Hongyou Fan, Margaret Werner-Washburne, Seema Singh, Gabriel P. Lopez, DeAnna M. Lopez, Darren R. Dunphy, Jeb H. Flemming, Carlee Erin Ashley, Nanguo Liu, C. Jeffrey Brinker
Publikováno v:
Science. 313:337-341
Amphiphilic phospholipids were used to direct the formation of biocompatible, uniform silica nanostructures in the presence of Saccharomyces cerevisiae and bacterial cell lines. The cell surfaces organize multilayered phospholipid vesicles that inter
Autor:
Peter D. Wentzell, Gabriel A. Quiñones, Jason A. Thomas, Anthony D. Aragon, Angelina L. Rodriguez, Chris Allen, Sushmita Roy, Brian Millier, Jason E. Jaetao, George S. Davidson, Margaret Werner-Washburne
Publikováno v:
Journal of Microbiological Methods. 65:357-360
Here we describe an automated, pressure-driven, sampling device for harvesting 10 to 30 ml samples, in replicate, with intervals as short as 10 s. Correlation between biological replicate time courses measured by microarrays was extremely high. The s
Publikováno v:
Sensors and Actuators B: Chemical. 113:376-381
We present and evaluate a new approach to cell immobilization for use in cell-based biosensors. We have fabricated a microfluidic channel using poly(dimethylsiloxane) (PDMS) with cell entrapment posts for the gentle packing and immobilization of yeas
Autor:
Frank Madeo, Stephanie W. Ruby, Osorio Meirelles, Chris Allen, Jason E. Jaetao, Margaret Werner-Washburne, Jason A. Thomas, Don Benn, Sabrina Büttner, Marten Veenhuis, Anthony D. Aragon
Publikováno v:
The Journal of Cell Biology
Journal of Cell Biology, 174(1), 89-100. ROCKEFELLER UNIV PRESS
Journal of Cell Biology, 174(1), 89-100. ROCKEFELLER UNIV PRESS
Quiescence is the most common and, arguably, most poorly understood cell cycle state. This is in part because pure populations of quiescent cells are typically difficult to isolate. We report the isolation and characterization of quiescent and nonqui