Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Margaret Vernier-Singer"'
Autor:
Xihui Sheng, Ursula Krotscheck, George Lust, Teresa M. Gunn, Steven G. Friedenberg, Seung Woo Jung, Elizabeth Corey, Patricia J. Fisher, Lan Zhu, Peter A. Schweitzer, Wendy Berg van den Foels, Nathan L. Dykes, Margaret Vernier-Singer, Wei Wang, Sean P. McDonough, Rory J. Todhunter, Zhiwu Zhang, Stuart P. Bliss, L.S. Hunter
Publikováno v:
American Journal of Veterinary Research. 72:530-540
Objective—To determine whether a mutation in the fibrillin 2 gene (FBN2) is associated with canine hip dysplasia (CHD) and osteoarthritis in dogs. Animals—-1,551 dogs. Procedures—Hip conformation was measured radiographically. The FBN2 was sequ
Autor:
Rory J. Todhunter, Keith E. Murphy, Kate L. Tsai, Raluca G. Mateescu, Margaret Vernier-Singer, Elizabeth Corey, Alma J. Williams, Nathan L. Dykes, Janjira Phavaphutanon, Peter A. Schweitzer, George Lust
Publikováno v:
American Journal of Veterinary Research. 70:1094-1101
Objective—To identify the quantitative trait loci (QTL) that contribute to hip dysplasia in dogs. Animals—192 Labrador Retrievers. Procedures—Hip dysplasia was measured by use of the Norberg angle (NA), dorsolateral subluxation (DLS) score, and
Autor:
Raluca G. Mateescu, Elizabeth Corey, George Lust, Gregory M. Acland, Janjira Phavaphutanon, Lan Zhu, Peter A. Schweitzer, Steven G. Friedenberg, Margaret Vernier-Singer, Rory J. Todhunter, Zhiwu Zhang, Alma J. Williams, F. Feng
Publikováno v:
Animal Genetics. 39:141-146
Hip laxity is one characteristic of canine hip dysplasia (CHD), an inheritable disease that leads to hip osteoarthritis. Using a genome-wide screen with 250 microsatellites in a crossbreed pedigree of 159 dysplastic Labrador retrievers and unaffected
Autor:
Sang Shin, Susan L. Fubini, Czeslaw Golkowski, Rory J. Todhunter, Margaret Vernier-Singer, Ashlee E. Watts
Publikováno v:
American Journal of Veterinary Research. 67:2030-2035
Objective—To determine the effect of nonthermal plasma on Staphylococcus aureus, fibroblasts in monolayer culture, and clean and contaminated skin explants. Sample Population—Normal skin from euthanized horses. Procedures—S aureus organisms wer
Autor:
Stuart P. Bliss, Alma J. Williams, George Casella, George Lust, Yrjö T. Gröhn, Nathan L. Dykes, Ashley Wilfand, Margaret Vernier-Singer, Nancy Burton-Wurster, Gregory M. Acland, Rory J. Todhunter, Rongling Wu
Publikováno v:
American Journal of Veterinary Research. 64:1472-1478
Objective—To determine the radiographic methods that best predict the development of osteoarthritis in the hip joints of a cohort of dogs with hip dysplasia and unaffected dogs. Animals—205 Labrador Retrievers, Greyhounds, and Labrador Retriever-
Autor:
Nancy Burton-Wurster, Margaret Vernier-Singer, Rory J. Todhunter, James N. MacLeod, Susan L. Fubini
Publikováno v:
Journal of Orthopaedic Research. 19:688-695
Experimental evidence suggests that recommended dosages of some corticosteroids used clinically as antiinflammatory agents for treating arthropathies damage articular cartilage, but low dosages may be chondroprotective. The purpose of this study was
Publikováno v:
Veterinary Surgery. 29:407-414
Objective— To study the effect of polysulfated glycosaminoglycan (PSGAG) on proteoglycan metabolism and DNA content of control and osteoarthritic (OA) cartilage. Study Design— An in vitro study comparing the effects of PSGAG on articular cartilag
Autor:
James P. Farese, Rory J. Todhunter, Robert O. Gilbert, Nancy Burton-Wurster, Michael Olivier, George Lust, Alma J. Williams, Gregory M. Acland, YT Grön, Margaret Vernier-Singer, Nathan L. Dykes
Publikováno v:
Journal of Heredity. 90:83-92
Canine hip dysplasia (CHD) is a prevalent, debilitating, polygenic disease characterized by hip subluxation and laxity which results in osteoarthritis. We are developing an informative pedigree for linkage analysis of CHD. The seven greyhound founder
Autor:
Rory J. Todhunter, Susan L. Fubini, Joyce A.M. Wootton, Margaret Vernier-Singer, Kathleen P. Freeman, George Lust, James N. MacLeod
Publikováno v:
Osteoarthritis and Cartilage. 6:94-105
Objective: To determine how acute synovitis, with and without intra-articular methylprednisolone acetate (MPA), affect synthesis of proteoglycan, total protein, and collagen in articular cartilage and total protein synthesis in synovial membrane. Des
Publikováno v:
Journal of Orthopaedic Research. 11:717-729
Full-thickness canine articular cartilage explants were subjected to compressive loads equivalent to a uniaxial stress of 0.025-1.2 MPa. A single cycle (18 h) of unconfined compression resulted in inhibition of total protein, proteoglycan, and fibron