Zobrazeno 1 - 10
of 50
pro vyhledávání: '"Margaret Tisdale"'
Publikováno v:
Antimicrobial Agents and Chemotherapy. 57:1677-1684
A zanamivir postapproval efficacy study was conducted in children ( n = 279) in Japan during three influenza seasons. Pharyngeal swab specimens ( n = 714) were obtained for detailed resistance analysis. From 371 cultured viruses, 3 viruses (A/H1N1) f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f11920a4bfa94575d40115aeae7714fd
https://doi.org/10.1128/aac.02145-12
https://doi.org/10.1128/aac.02145-12
Autor:
Craig LaForce, Choy Y. Man, Laila Kudule, Frederick W. Henderson, Frank C. Hampel, Margaret Tisdale, Julia Harris, Alison Webster, Janet E. McElhaney, Robert B. Bettis, Philip Yates
Publikováno v:
Clinical Therapeutics. 29:1579-1590
Influenza can cause significant morbidity and mortality in subjects at high risk for complications, including the elderly (ageor=65 years) and those with chronic respiratory, cardiovascular, or metabolic conditions. Effective prophylaxis can signific
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b8d53afb04e05fb75d9107022e7a27bc
https://doi.org/10.1016/j.clinthera.2007.08.023
https://doi.org/10.1016/j.clinthera.2007.08.023
Autor:
Phillip J. Yates, Jennifer L. McKimm-Breschkin, Janet M. Daly, Matthew S. Walters, Margaret Tisdale, Thomas Zürcher, Anjali Sahasrabudhe, Laura Dash
Publikováno v:
Journal of Antimicrobial Chemotherapy. 58:723-732
Background: Viruses resistant to zanamivir have been generated in vitro, but no resistant virus has yet been isolated from a zanamivir-treated immunocompetent patient. In contrast most resistant viruses isolated from oseltamivir-treated patients corr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b2c71a9b8e1060a0324f8e07e4b146e
https://doi.org/10.1093/jac/dkl321
https://doi.org/10.1093/jac/dkl321
Publikováno v:
Journal of Antimicrobial Chemotherapy. 52:319-323
One of the major challenges to the successful long-term treatment ofHIV-1 infection is overcoming the development of increasing levelsof antiretroviral resistance that often accompany the failure of suc-cessive treatment regimens. In order to meet th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::929f7bc9b7497be7019dcd09cad38698
https://doi.org/10.1093/jac/dkg392
https://doi.org/10.1093/jac/dkg392
Autor:
Peter J. Morley, David Gower, Ian J. Owens, Robert J. Fenton, Anne-Marie Bourgault, Yacine Abed, Guy Boivin, Margaret Tisdale
Publikováno v:
The Journal of Infectious Diseases. 186:1074-1080
Previous studies have shown that amino acid changes in the hemagglutinin (HA) gene of influenza viruses may result in decreased susceptibility to neuraminidase inhibitors (NAIs) in vitro. However, the emergence and characteristics of such HA variants
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07579603f0df51b7999a3d7c304c1981
https://doi.org/10.1086/344237
https://doi.org/10.1086/344237
Autor:
Wendy Harris, Jane Yeo, Robert Elston, Fan Xu, Sharon Randall, Michael F. Maguire, Margaret Tisdale, Varsha Manohitharajah, Wendy Snowden, Astrid Klein, Hayley Parker, Jackie May, Denise D Shortino
Publikováno v:
Antimicrobial Agents and Chemotherapy. 46:731-738
Previous data have indicated that the development of resistance to amprenavir, an inhibitor of the human immunodeficiency virus type 1 protease, is associated with the substitution of valine for isoleucine at residue 50 (I50V) in the viral protease.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::698eb590123aafb3a73e29407f2d4f09
https://doi.org/10.1128/aac.46.3.731-738.2002
https://doi.org/10.1128/aac.46.3.731-738.2002
Autor:
Philip Griffin, Judith Falloon, Abdelrahim Rakik, Margaret Tisdale, Mounir Ait-Khaled, Naomi Richards, Deborah A. Thomas, Chris Stone
Publikováno v:
Antiviral Therapy. 8:111-120
Objective To determine HIV-1 reverse transcriptase (RT) and protease (PRO) mutations selected in isolates from antiretroviral therapy (ART)-experienced patients receiving an efavirenz/abacavir/amprenavir salvage regimen. Methods Open-label, single ar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::97fdeb2f6b54207a5c54d883f8bbd157
https://doi.org/10.1177/135965350300800205
https://doi.org/10.1177/135965350300800205
Publikováno v:
International Congress Series. 1219:879-886
Various phenotypic methods have been used to monitor viral susceptibility to anti-viral agents in the management of virus diseases. Confirmation of resistance generally requires genotyping of the inhibitor target gene(s) and identification of mutatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6f097984274f555f60cc05e609e71ccd
https://doi.org/10.1016/s0531-5131(01)00656-2
https://doi.org/10.1016/s0531-5131(01)00656-2
Autor:
Richard Haubrich, Grace Pagano, Judith Millard, William Lang, Joseph J. Eron, Josie Wolfram, Wendy Snowden, Margaret Tisdale, Louise Pedneault
Publikováno v:
Journal of Acquired Immune Deficiency Syndromes. 26:458-461
This study evaluated dual protease inhibitor (PI) regimens containing amprenavir (APV) in PI-naive, HIV-1-infected patients over 48 weeks. Patients were randomized to 800-mg APV combined with 800-mg indinavir (IDV), 750-mg nelfinavir (NFV), or 800-mg
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c41a5af214c476018677668bce746bd
https://doi.org/10.1097/00042560-200104150-00008
https://doi.org/10.1097/00042560-200104150-00008