Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Margaret T. Weis"'
Autor:
Margaret T. Weis, Yousuf Ali
Publikováno v:
The FASEB Journal. 33
Autor:
Nina Blakeman, Man Zhang, Qian Chen, Margaret T. Weis, Duy H. Hua, Hung Pham, Palika Datta, Allan M. Prior, Lindon H. Young
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 24:1057-1061
Various triacsin C analogs, containing different alkenyl chains and carboxylic acid bioisoteres including 4-aminobenzoic acid, isothiazolidine dioxide, hydroxylamine, hydroxytriazene, and oxadiazolidine dione, were synthesized and their inhibitions o
Autor:
Nina Blakeman, Qian Chen, Jasmine Tolson, Brian Rueter, Brian Diaz, Brendan Casey, Lindon H. Young, Margaret T. Weis
Publikováno v:
American Journal of Biomedical Sciences. :249-261
Publikováno v:
American Journal of Biomedical Sciences. :40-49
Vascular endothelial dysfunction is a common and early event occurring in many disease conditions, such as ischemia/reperfusion (I/R) injury, vascular complications of diabetes, and clinical procedures that injure blood vessels. The hallmark of endot
Publikováno v:
Neurochemistry International. 56:501-507
In a rat model of neuroinflammation, produced by a 6-day intracerebral ventricular infusion of bacterial lipopolysaccharide (LPS), we reported that the brain concentrations of non-esterified brain arachidonic acid (AA, 20:4 n-6) and its eicosanoid pr
Autor:
Margaret T. Weis, Palika Datta
Publikováno v:
The FASEB Journal. 29
Publikováno v:
Cardiovascular Drug Reviews. 23:255-272
Reperfusion injury is characterized by a decrease in endothelial release of nitric oxide within 5 min after reperfusion, increased leukocyte-endothelium interaction, and transmigration of leukocytes into the myocardium, producing cardiac contractile
Publikováno v:
Journal of Vascular Research. 42:275-283
Background: Triacsin C, a fatty acid analog, inhibits endothelial nitric oxide synthetase (eNOS) palmitoylation, increases nitric oxide synthesis and enhances methacholine-induced relaxation of vascular rings. The experiments presented here tested th
Publikováno v:
Cardiovascular Research. 63:338-346
Objectives: Endothelial nitric oxide synthase (eNOS) activation/deactivation is associated with cyclic depalmitoylation/repalmitoylation of specific Cys residues. The mechanism of depalmitoylation has been identified recently, but repalmitoylation re
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics. 1645:193-204
The formation of coenzyme A thioesters from long-chain fatty acids represents a metabolic branch point. We have isolated, cloned and sequenced a long-chain fatty acyl CoA synthetase (LCFACoAS) that is localized to the endothelium of rabbit heart and