Výsledky vyhledávání - "Margaret S. Lin"

Host cell protein testing by ELISAs and the use of orthogonal methods

Autor: Robert M. Wong, Julie C. Nishihara, Christopher Yu, Peter Liu, Judith Zhu-Shimoni, Feny Gunawan, Martin Vanderlaan, Wendy Sandoval, Margaret S. Lin, Denise C. Krawitz

Publikováno v: Biotechnology and Bioengineering. 111:2367-2379

Host cell proteins (HCPs) are among the process-related impurities monitored during recombinant protein pharmaceutical process development. The challenges of HCP detection include (1) low levels of residual HCPs present in large excess of product pro

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::7a05a416ca5a5fa3f9a75423227c0058
https://doi.org/10.1002/bit.25327

Zobrazit plný text záznamu

Local calcium transients contribute to disappearance of pFAK, focal complex removal and deadhesion of neuronal growth cones and fibroblasts

Autor: Nicholas C. Spitzer, Matthew W. Conklin, Margaret S. Lin

Publikováno v: Developmental Biology. 287:201-212

Cell adhesion is crucial for migration of cells during development, and cell–substrate adhesion of motile cells is accomplished through the formation and removal of focal complexes that are sites of cell–substrate contact. Because Ca2+ signaling

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d4f69bd8108ee1faf602e0bd3f4728ab
https://doi.org/10.1016/j.ydbio.2005.09.006

Zobrazit plný text záznamu

Energy dependence of the fragmentation of the n-butylbenzene molecular ion

Autor: Margaret S. Lin, Alex G. Harrison

Publikováno v: International Journal of Mass Spectrometry and Ion Physics. 51:353-356

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::52b588edfa15b06b855fb81fc6d8f351
https://doi.org/10.1016/0020-7381(83)85018-9

Zobrazit plný text záznamu

Mass spectrometry of compounds of the type [Fe(CO)2(η-C5H5)R](R = alkyl)

Autor: David E. Laycock, Michael C. Baird, Margaret S. Lin, John A. Stone

Publikováno v: J. Chem. Soc., Dalton Trans.. :2488-2492

The electron-impact mass spectra of a series of compounds of the type [Fe(CO)2(η-C5H5)R](R = alkyl) have been obtained. Three major fragmentation routes commence with loss of alkyl (R), alkene (R–H), or carbonyl groups. Particularly intense peaks

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::5542602df0e52dfea8684780be1f887d
https://doi.org/10.1039/dt9800002488

Zobrazit plný text záznamu

Effect of protonation exothermicity on the reaction of gaseous Brønsted acids with halobenzene derivatives

Autor: A. G. Harrison, Margaret S. Lin, Wie Giap Liauw

Publikováno v: Organic Mass Spectrometry. 16:383-387

The protonation of haloaromatics by [N2H]+ and [CO2H]+ has been studied by chemical ionization mass spectrometry. In general, the fragmentation reactions following protonation by [CO2H]+ are similar to those observed following protonation by [CH5]+,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::defc475ce0ef95166b8f486fc1cace49
https://doi.org/10.1002/oms.1210160904

Zobrazit plný text záznamu

Stereochemical applications of mass spectrometry. 3—Energy dependence of the fragmentation of stereoisomeric methylcyclohexanols

Autor: Alex G. Harrison, Margaret S. Lin

Publikováno v: Organic Mass Spectrometry. 19:67-71

Breakdown graphs have been constructed from charge exchange data for the epimeric 2-methyl-, 3-methyl- and 4-methyl-cyclohexanols. Although the breakdown graphs for epimeric pairs are essentially identical above ∼12 eV recombination energy, signifi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::f2357a351bf472424ff9d16cd0f35de0
https://doi.org/10.1002/oms.1210190204

Zobrazit plný text záznamu

Rearrangement Reactions in the Electron Impact Fragmentation of Isobutene

Autor: Alex G. Harrison, Margaret S. Lin

Publikováno v: Canadian Journal of Chemistry. 52:1813-1820

The detailed mass spectrum of isobutene has been examined using both D and 13C labelling. It is shown that at low average internal energies of the molecular ion complete randomization of hydrogens and of carbons occurs prior to fragmentation to form

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::297a5a6b2563685dc998e9c63ecf32d2
https://doi.org/10.1139/v74-260

Zobrazit plný text záznamu

The formation and reactions of aromatic dimer cations in a high pressure photoionization source

Autor: John A. Stone, Margaret S. Lin

Publikováno v: Canadian Journal of Chemistry. 58:1666-1672

Aromatic dimer cations (M2+) have been generated for a series of aromatic compounds in a high pressure photoionization source. Relative third order rate constants for formation of M2+ have been obtained for benzene (1.0), benzene-d6 (2.7), toluene (0

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::f8b1cf2e1bd2c3451733eec3d7cd90e4
https://doi.org/10.1139/v80-266

Zobrazit plný text záznamu

Ion–molecule reactions in dimethylsulfoxide by high pressure photoionization mass spectrometry

Autor: John A. Stone, Margaret S. Lin

Publikováno v: Canadian Journal of Chemistry. 58:376-380

Dimethylsulfoxide (DMSO) has been photoionized at 10.0 and 11.7 eV over the pressure range 0.3–210 mTorr. The rate constant for the disappearance of DMSO+ is 1.0 × 10−9 cm3 molecule−1 s−1, independent of photon energy. The major products at

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::e34e5c3e9ece6d53f233a3091803a644
https://doi.org/10.1139/v80-060

Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání