Zobrazeno 1 - 10
of 47
pro vyhledávání: '"Margaret S. Bynoe"'
Autor:
Luisa Torres, Sudie-Ann Robinson, Do-Geun Kim, Angela Yan, Thomas A. Cleland, Margaret S. Bynoe
Publikováno v:
Journal of Neuroinflammation, Vol 15, Iss 1, Pp 1-19 (2018)
Abstract Background Alzheimer’s disease (AD) is a progressive neurodegenerative disease associated with cognitive decline and complete loss of basic functions. The ubiquitous apicomplexan parasite Toxoplasma gondii (T. gondii) infects up to one thi
Externí odkaz:
https://doaj.org/article/6e2823bf1d9d4f1580b937bb95983a64
Autor:
Francesca Bosetti, Zorina S. Galis, Margaret S. Bynoe, Marc Charette, Marilyn J. Cipolla, Gregory J. del Zoppo, Douglas Gould, Thomas S. Hatsukami, Teresa L. Z. Jones, James I. Koenig, Gerard A. Lutty, Christine Maric‐Bilkan, Troy Stevens, H. Eser Tolunay, Walter Koroshetz
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 5, Iss 11 (2016)
Externí odkaz:
https://doaj.org/article/567bacc8d4b94e2b9ad015576c994658
Autor:
Linda F. Thompson, Andrew D. Miller, Angela Yan, Michelle L. Joachims, Margaret S. Bynoe, Peter Canoll
Publikováno v:
The Journal of Neuroscience. 39:4387-4402
Glioblastoma (GB) is one of the deadliest brain cancers to afflict humans, and it has a very poor survival rate even with treatment. The extracellular adenosine-generating enzyme CD73 is involved in many cellular functions that can be usurped by tumo
Autor:
Do-Geun Kim, Mark S. Roberson, Amy M. Navratil, Abigail R. Dowling, Jessica L. Brown, Margaret S. Bynoe, Jianjun Xie, Kurt Scavelli, Krystal Allen-Worthington, Iain J. Clarke, Alexa M. Edmunson, Hojean Yoon
Publikováno v:
Molecular Endocrinology. 30:996-1011
Fertility in mammals requires appropriate communication within the hypothalamic-pituitary-gonadal axis and the GnRH receptor (GnRHR) is a central conduit for this communication. The GnRHR resides in discrete membrane rafts and raft occupancy is requi
Autor:
Thomas A. Cleland, Luisa Torres, Sudie-Ann Robinson, Do-Geun Kim, Margaret S. Bynoe, Angela Yan
Publikováno v:
Journal of Neuroinflammation, Vol 15, Iss 1, Pp 1-19 (2018)
Journal of Neuroinflammation
Journal of Neuroinflammation
Background Alzheimer’s disease (AD) is a progressive neurodegenerative disease associated with cognitive decline and complete loss of basic functions. The ubiquitous apicomplexan parasite Toxoplasma gondii (T. gondii) infects up to one third of the
Publikováno v:
Infection and Immunity. 83:721-729
As an obligate intracellular pathogen, the apicomplexan parasite Toxoplasma gondii evades immune system-mediated clearance by undergoing stage differentiation to persist indefinitely in susceptible hosts. Previously, we found that mice deficient in t
Autor:
Margaret S. Bynoe, Do-Geun Kim
Publikováno v:
Molecular Neurobiology. 52:664-678
The blood brain barrier (BBB) symbolically represents the gateway to the central nervous system. It is a single layer of specialized endothelial cells that coats the central nervous system (CNS) vasculature and physically separates the brain environm
Autor:
Margaret S Bynoe
Publikováno v:
The Journal of Immunology. 202:116.11-116.11
Multiple sclerosis (MS) is a is a chronic, debilitating, neuroinflammatory disease that affects the central nervous system (CNS). MS affects about 2.5 million patients world-wide. MS patients experience a progressive loss in neurological function cau
Publikováno v:
The Journal of Immunology. 191:3764-3777
Activated protein C (PC) is an anticoagulant involved in the interactions between the coagulation and immune systems. Activated PC has broad anti-inflammatory effects that are mediated through its ability to modulate leukocyte function and confer vas
Autor:
Elisabete Augusto, Ali El-Tayeb, Christa E. Müller, Margaret S. Bynoe, Marco Matos, Rodrigo A. Cunha, Jean Sévigny, Jiang-Fan Chen
Publikováno v:
Journal of Neuroscience. 33:11390-11399
Adenosine is a neuromodulator acting through inhibitory A1 receptors (A1Rs) and facilitatory A2ARs, which have similar affinities for adenosine. It has been shown that the activity of intracellular adenosine kinase preferentially controls the activat