Zobrazeno 1 - 10
of 138
pro vyhledávání: '"Margaret S Cheung"'
Publikováno v:
PLoS Computational Biology, Vol 18, Iss 5, p e1010105 (2022)
Actin networks are essential for living cells to move, reproduce, and sense their environments. The dynamic and rheological behavior of actin networks is modulated by actin-binding proteins such as α-actinin, Arp2/3, and myosin. There is experimenta
Externí odkaz:
https://doaj.org/article/64664ff5e052497fb4e98d5ca5e5d59f
Publikováno v:
PLoS Computational Biology, Vol 7, Iss 7, p e1002114 (2011)
The flexibility in the structure of calmodulin (CaM) allows its binding to over 300 target proteins in the cell. To investigate the structure-function relationship of CaM, we combined methods of computer simulation and experiments based on circular d
Externí odkaz:
https://doaj.org/article/6edcb134dcbb4612b37be7704b0fa8fe
Publikováno v:
The Journal of Physical Chemistry B. 127:2900-2908
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::259c979ba123df4956d9e93ab6cc7a36
https://doi.org/10.1021/acs.jpcb.2c08734
https://doi.org/10.1021/acs.jpcb.2c08734
Publikováno v:
Physical Review Research, Vol 3, Iss 3, p 033220 (2021)
Inside a cell, heterotypic proteins assemble in inhomogeneous, crowded systems where the abundance of these proteins vary with cell types. While some protein complexes form putative structures that can be visualized with imaging, there are far more p
Externí odkaz:
https://doaj.org/article/d338e448731149c7b3a45bc40b1a3bed
Publikováno v:
The Journal of Physical Chemistry B. 126:4458-4471
The neurodegenerative disease amyotrophic lateral sclerosis (ALS) is associated with the misfolding and aggregation of the metalloenzyme protein superoxide dismutase 1 (SOD1) via mutations that destabilize the monomer-dimer interface. In a cellular e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::32445298474c32faef70dd690446f116
https://doi.org/10.1021/acs.jpcb.2c00819
https://doi.org/10.1021/acs.jpcb.2c00819
Publikováno v:
Cancer Informatics, Vol 2016, Iss 15, Pp 1-13 (2016)
Externí odkaz:
https://doaj.org/article/f2bf36625994481bbc44b98961d20f1b
Autor:
Jacob Tinnin, Srijana Bhandari, Pengzhi Zhang, Eitan Geva, Barry D. Dunietz, Xiang Sun, Margaret S. Cheung
Publikováno v:
The Journal of Physical Chemistry Letters. 13:763-769
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4d2eff7afe913dea6ba6df678cbb2b70
https://doi.org/10.1021/acs.jpclett.1c03618
https://doi.org/10.1021/acs.jpclett.1c03618
Publikováno v:
Protein Science. 32
In this study, we present a method of pattern mining based on network theory that enables the identification of protein structures or complexes from synthetic volume densities, without the knowledge of predefined templates or human biases for refinem
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::01ff1f45dc2075c67d30132a2c8eebae
https://doi.org/10.1002/pro.4538
https://doi.org/10.1002/pro.4538
Publikováno v:
The Journal of Physical Chemistry B. 125:3501-3509
Pseudomonas aeruginosa apoazurin (apo, without the copper cofactor) has a single disulfide bond between residues 3 and 26 and unfolds in a two-state reaction in vitro. The disulfide bond covalently connects the N-termini of β-strands 1 and 3; thereb
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::043fe3ffcd9c751834c2b653664122e9
https://doi.org/10.1021/acs.jpcb.1c00219
https://doi.org/10.1021/acs.jpcb.1c00219
Publikováno v:
The Journal of Physical Chemistry B. 124:9579-9591
The nonequilibrium Fermi's golden rule (NE-FGR) describes the time-dependent rate coefficient for electronic transitions when the nuclear degrees of freedom start out in a nonequilibrium state. In this paper, the linearized semiclassical (LSC) approx
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::79d3b5f89df9f68bc5cbde7b72f47fc9
https://doi.org/10.1021/acs.jpcb.0c06306
https://doi.org/10.1021/acs.jpcb.0c06306