Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Margaret S, Merrill"'
Autor:
Viktor A. Adalsteinsson, Gavin Ha, Samuel S. Freeman, Atish D. Choudhury, Daniel G. Stover, Heather A. Parsons, Gregory Gydush, Sarah C. Reed, Denisse Rotem, Justin Rhoades, Denis Loginov, Dimitri Livitz, Daniel Rosebrock, Ignaty Leshchiner, Jaegil Kim, Chip Stewart, Mara Rosenberg, Joshua M. Francis, Cheng-Zhong Zhang, Ofir Cohen, Coyin Oh, Huiming Ding, Paz Polak, Max Lloyd, Sairah Mahmud, Karla Helvie, Margaret S. Merrill, Rebecca A. Santiago, Edward P. O’Connor, Seong H. Jeong, Rachel Leeson, Rachel M. Barry, Joseph F. Kramkowski, Zhenwei Zhang, Laura Polacek, Jens G. Lohr, Molly Schleicher, Emily Lipscomb, Andrea Saltzman, Nelly M. Oliver, Lori Marini, Adrienne G. Waks, Lauren C. Harshman, Sara M. Tolaney, Eliezer M. Van Allen, Eric P. Winer, Nancy U. Lin, Mari Nakabayashi, Mary-Ellen Taplin, Cory M. Johannessen, Levi A. Garraway, Todd R. Golub, Jesse S. Boehm, Nikhil Wagle, Gad Getz, J. Christopher Love, Matthew Meyerson
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-13 (2017)
Identifying the mutational landscape of tumours from cell-free DNA in the blood could help diagnostics in cancer. Here, the authors present ichorCNA, software that quantifies tumour content in cell free DNA, and they demonstrate that cell-free DNA wh
Externí odkaz:
https://doaj.org/article/8356e743a9994304930b464f7882be11
Autor:
Ethan Cerami, Bruce E. Johnson, Sara M. Tolaney, Ian E. Krop, Laura E. MacConaill, Ron Bose, Margaret S. Merrill, Nicole Kuhnly, Tianyu Li, Romualdo Barroso-Sousa, Pedro Exman, Janet Files, Neal I. Lindeman, Simona Di Lascio, Cynthia X. Ma, Nan Lin, Nikhil Wagle, Deborah A. Dillon, Rebecca A. Santiago, Eric P. Winer, Brittany L. Bychkovsky, Max Lloyd, Priti Kumari, Lindsey M. Crowley, Ana C. Garrido-Castro, Melissa E. Hughes, Colin Mackichan, Max Krevalin, Rachel A. Freedman, Lorenzo Trippa
Publikováno v:
JCO Precision Oncology. :1-9
PURPOSE The yield of comprehensive genomic profiling in recruiting patients to molecular-based trials designed for small subgroups has not been fully evaluated. We evaluated the likelihood of enrollment in a clinical trial that required the identific
Autor:
Pedro, Exman, Ana C, Garrido-Castro, Melissa E, Hughes, Rachel A, Freedman, Tianyu, Li, Lorenzo, Trippa, Brittany L, Bychkovsky, Romualdo, Barroso-Sousa, Simona, Di Lascio, Colin, Mackichan, Max R, Lloyd, Max, Krevalin, Ethan, Cerami, Margaret S, Merrill, Rebecca, Santiago, Lindsey, Crowley, Nicole, Kuhnly, Janet, Files, Neal I, Lindeman, Laura E, MacConaill, Priti, Kumari, Sara M, Tolaney, Ian E, Krop, Ron, Bose, Bruce E, Johnson, Cynthia X, Ma, Deborah A, Dillon, Eric P, Winer, Nikhil, Wagle, Nancy U, Lin
Publikováno v:
JCO Precis Oncol
PURPOSE: The yield of comprehensive genomic profiling in recruiting patients to molecular-based trials designed for small subgroups has not been fully evaluated. We evaluated the likelihood of enrollment in a clinical trial that required the identifi
Autor:
Zhenwei Zhang, Laura Polacek, Sara M. Tolaney, Joshua M. Francis, Samuel S. Freeman, Paz Polak, Rachel Leeson, J. Christopher Love, Huiming Ding, Sairah Mahmud, Nelly Oliver, Rachel M. Barry, Atish D. Choudhury, Levi A. Garraway, Gregory Gydush, Andrea Saltzman, Eliezer M. Van Allen, Coyin Oh, Viktor A. Adalsteinsson, Justin Rhoades, Jesse S. Boehm, Sarah C. Reed, Seong Ho Jeong, Todd R. Golub, Karla Helvie, Matthew Meyerson, Lauren C. Harshman, Gad Getz, Ignaty Leshchiner, Jens G. Lohr, Chip Stewart, Heather A. Parsons, Jaegil Kim, Adrienne G. Waks, Mari Nakabayashi, Lori Marini, Mara Rosenberg, Edward P. O’Connor, Daniel Rosebrock, Denis Loginov, Daniel G. Stover, Rebecca A. Santiago, Nikhil Wagle, Joseph F. Kramkowski, Mary-Ellen Taplin, Eric P. Winer, Nan Lin, Ofir Cohen, Cheng-Zhong Zhang, Dimitri Livitz, Emily Lipscomb, Gavin Ha, Molly Schleicher, Denisse Rotem, Max Lloyd, Margaret S. Merrill, Cory M. Johannessen
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-13 (2017)
Nature Communications
Nature Communications
Whole-exome sequencing of cell-free DNA (cfDNA) could enable comprehensive profiling of tumors from blood but the genome-wide concordance between cfDNA and tumor biopsies is uncertain. Here we report ichorCNA, software that quantifies tumor content i
Autor:
Dana Farengo Clark, Judy Garber, Jada G. Hamilton, Sarah R. Kane, Fergus J. Couch, Temima Wildman, Susan M. Domchek, Kenneth Offit, Margaret S. Merrill, Jamie Brower, Jessica Ebrahimzadeh, Mark E. Robson, Pauleen Sanchez
Publikováno v:
Journal of Clinical Oncology. 38:e13680-e13680
e13680 Background: Multiplex genetic testing (MGT) simultaneously analyzes multiple cancer susceptibility genes and can reveal genetic variants of uncertain significance (VUS) that have unclear associations with cancer risks. Little is known about ho
Autor:
Mark E. Robson, Judith Balmaña, Michael Francis Walsh, Tricia Harstad, Kenneth Offit, Judy Garber, Susan M. Domchek, Jada G. Hamilton, Margaret S. Merrill, Jamie Brower, Heather Symecko
Publikováno v:
Journal of Clinical Oncology. 37:1527-1527
1527 Background: Prospective Registry of Multiplex Testing (PROMPT) is an online registry for individuals who have had multiplex panel testing for cancer susceptibility. The main objective of this registry is to ascertain families to allow penetrance