Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Margaret R. Folaron"'
Autor:
Boyu Meng, Margaret R Folaron, Brook K Byrd, Kimberley S Samkoe, Rendall S Strawbridge, Connor Barth, Summer L Gibbs, Scott C Davis
Publikováno v:
PLoS ONE, Vol 15, Iss 3, p e0230267 (2020)
PurposeRapid, intra-operative identification of tumor tissue in the margins of excised specimens has become an important focus in the pursuit of reducing re-excision rates, especially for breast conserving surgery. Dual-probe difference specimen imag
Externí odkaz:
https://doaj.org/article/c0200953772f4024b660cd33c8dabb41
Autor:
Boyu Meng, Kenneth M. Tichauer, Kimberley S. Samkoe, Negar Sadeghipour, Margaret R. Folaron, Rendall R. Strawbridge, Scott C. Davis
Publikováno v:
Molecular Imaging and Biology
Purpose The ability to noninvasively quantify receptor availability (RA) in solid tumors is an aspirational goal of molecular imaging, often challenged by the influence of non-specific accumulation of the contrast agent. Paired-agent imaging (PAI) te
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f1a59386f1c0507bf9faf2dd65047abf
https://doi.org/10.1007/s11307-021-01629-6
https://doi.org/10.1007/s11307-021-01629-6
Autor:
Negar Sadeghipour, Margaret R. Folaron, Scott C. Davis, Kimberley S. Samkoe, Boyu Meng, Rendall R. Strawbridge, Kenneth M. Tichauer
Publikováno v:
Theranostics
Immuno-oncological treatment strategies that target abnormal receptor profiles of tumors are an increasingly important feature of cancer therapy. Yet, assessing receptor availability (RA) and drug-target engagement, important determinants of therapeu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18862cb67af7166d12324cbcc82189a0
https://doi.org/10.7150/thno.45273
https://doi.org/10.7150/thno.45273
Autor:
Xiaochun Xu, Eunice Y. Chen, P. Jack Hoopes, Jason R. Gunn, Margaret R. Folaron, Sassan Hodge, Kenneth M. Tichauer, Cheng Wang, Kimberley S. Samkoe
Publikováno v:
Molecular imaging and biology.
Purpose The goal of fluorescence-guided surgery (FGS) in oncology is to improve the surgical therapeutic index by enhancing contrast between cancerous and healthy tissues. However, optimal discrimination between these tissues is complicated by the no
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a1ba4efb82d3338bca28edb14c01095
https://pubmed.ncbi.nlm.nih.gov/34651290
https://pubmed.ncbi.nlm.nih.gov/34651290
Autor:
Margaret R. Folaron, Kimberley S. Samkoe, Kenneth M. Tichauer, Sassan Hodge, Eunice Y. Chen, Jason R. Gunn, P. Jack Hoopes, Cheng Wang
Background: The goal of fluorescence guided surgery (FGS) in oncology is to improve the surgical therapeutic index by enhancing contrast between cancerous and healthy tissue. However, optimal discrimination between these tissues is complicated by the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c3183bd358d6bf0f143e24e22d338293
https://doi.org/10.21203/rs.3.rs-111011/v1
https://doi.org/10.21203/rs.3.rs-111011/v1
Autor:
Rendall R. Strawbridge, Margaret R. Folaron, Scott C. Davis, Negar Sadeghipour, Kimberley S. Samkoe, Aakanksha Rangnekar, Kenneth M. Tichauer
Publikováno v:
Journal of Biomedical Optics
Significance: Fluorescence guidance in cancer surgery (FGS) using molecular-targeted contrast agents is accelerating, yet the influence of individual patients’ physiology on the optimal time to perform surgery post-agent-injection is not fully unde
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a08fcf39120f91ed5757aaf2911b1d64
https://pubmed.ncbi.nlm.nih.gov/33200596
https://pubmed.ncbi.nlm.nih.gov/33200596
Autor:
Scott C. Davis, Kimberley S. Samkoe, Boyu Meng, Kenneth M. Tichauer, Margaret R. Folaron, Rendall R. Strawbridge
Publikováno v:
Proc SPIE Int Soc Opt Eng
Optical tomography is often coupled with high resolution imaging modality like MRI to provide functional information associated with specific anatomical structure noninvasively. MRI-coupled paired agent fluorescence molecular tomography (MRI-PAFT) is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::430046efa6aaa4ad86c49c2f498e8af3
https://doi.org/10.1117/12.2547083
https://doi.org/10.1117/12.2547083
Autor:
Cheng Wang, Eunice Y. Chen, P. Jack Hoopes, Margaret R. Folaron, Kimberley S. Samkoe, Kenneth M. Tichauer
Publikováno v:
Biophotonics Congress: Biomedical Optics 2020 (Translational, Microscopy, OCT, OTS, BRAIN).
Paired agent imaging demonstrates comparable accuracy with immunohistochemistry, but more time-efficient, and labor-saving. It may open up a new chapter for biopsy screening and intra-operative margin detection.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f48749545dfcb67a7f1977ec950ee563
https://doi.org/10.1364/translational.2020.ttu4b.3
https://doi.org/10.1364/translational.2020.ttu4b.3
Autor:
Scott C. Davis, Brook K. Byrd, Rendall S. Strawbridge, Caroline E. Filan, Dennis J. Wirth, Margaret R. Folaron
Publikováno v:
Proceedings of SPIE--the International Society for Optical Engineering. 10862
Short-wave infrared imaging in tissue in the 1000–2000 nm range is characterized by reduced photon scatter and comparable or higher absorption compared to the NIR-I regime. These characteristics have implications for the performance of fluorescence
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9714e3cbf6f1b418b455e6ae46510edc
https://pubmed.ncbi.nlm.nih.gov/31723310
https://pubmed.ncbi.nlm.nih.gov/31723310
Publikováno v:
Cancers
Volume 11
Issue 7
Cancers, Vol 11, Iss 7, p 951 (2019)
Volume 11
Issue 7
Cancers, Vol 11, Iss 7, p 951 (2019)
Head and neck squamous cell carcinomas (HNSCC) represent a group of epithelial neoplasms that exhibit considerable heterogeneity in clinical behavior. Here, we examined the stromal and vascular heterogeneity in a panel of patient-derived xenograft (P
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f32d4844de12a7bcdf611a34c099d28a
http://europepmc.org/articles/PMC6679003
http://europepmc.org/articles/PMC6679003