Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Margaret R. Connolly"'
Autor:
Parth M. Patel, Margaret R. Connolly, Taylor M. Coe, Anthony Calhoun, Franziska Pollok, James F. Markmann, Lars Burdorf, Agnes Azimzadeh, Joren C. Madsen, Richard N. Pierson
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
The recent dramatic advances in preventing “initial xenograft dysfunction” in pig-to-non-human primate heart transplantation achieved by minimizing ischemia suggests that ischemia reperfusion injury (IRI) plays an important role in cardiac xenotr
Externí odkaz:
https://doaj.org/article/2e745c8bbe684164a9bafb1d612a12ec
Autor:
Allison S. Letica-Kriegel, Margaret R. Connolly, Maggie L. Westfal, David Treadway, Lisa Post, John T. Mullen, Motaz Qadan
Publikováno v:
Journal of Surgical Education.
Autor:
Agnes Azimzadeh, Donald G. Harris, Margaret R. Connolly, Richard N. Pierson, David Ayares, Zahra Alikhassy Habibabady, Dawn Parsell, Emily Redding, Arielle Cimeno, Carol Phelps, Christopher Laird, Lars Burdorf, Natalie A. O'Neill
Publikováno v:
Am J Transplant
Galactosyl transferase knock-out pig lungs fail rapidly in baboons. Based on previously identified lung xenograft injury mechanisms, additional expression of human complement and coagulation pathway regulatory proteins, anti-inflammatory enzymes and
Autor:
Ryan Chaban, Zahra Habibabady, Wessam Hassanein, Margaret R. Connolly, Lars Burdorf, Emily Redding, Christopher Laird, Jolene Ranek, Gheorghe Braileanu, Selin Sendil, Xiangfei Cheng, Wenji Sun, Natalie A. O'Neill, Kasinath Kuravi, Sunghoon Hurh, David L. Ayares, Agnes M. Azimzadeh, Richard N. Pierson
Publikováno v:
Xenotransplantation. 29
Antibody-mediated rejection has long been known to be one of the major organ failure mechanisms in xenotransplantation. In addition to the porcine α1,3-galactose (α1,3Gal) epitope, N-Glycolylneuraminic acid (Neu5Gc), a sialic acid, has been identif
Autor:
Kaitlyn Petitpas, Zahra Habibabady, Veronica Ritchie, Margaret R. Connolly, Lars Burdorf, Wenning Qin, Yinan Kan, Jacob V. Layer, Juliet N. Crabtree, Michele E. Youd, William F. Westlin, Diogo M. Magnani, Richard N. Pierson, Agnes M. Azimzadeh
Publikováno v:
XenotransplantationREFERENCES.
The phenomenon of diminishing hematocrit after in vivo liver and lung xenotransplantation and during ex vivo liver xenoperfusion has largely been attributed to action by resident liver porcine macrophages, which bind and destroy human erythrocytes. P
Autor:
Margaret R. Connolly, Richard N. Pierson, Jay A. Fishman, Lars Burdorf, David A. D'Alessandro, Agnes Azimzadeh, Joren C. Madsen, Gregory D. Lewis
Publikováno v:
Circulation
Consistent survival of life-supporting pig heart xenograft recipients beyond 90 days was recently reported using genetically modified pigs and a clinically applicable drug treatment regimen. If this remarkable achievement proves reproducible, publish
Autor:
Tiezheng Li, Todd Vaught, Margaret R. Connolly, Lars Burdorf, Selin Sendil, Arielle Cimeno, John C. LaMattina, Zahra Alikhassy Habibabady, Jeffery Monahan, Agnes Azimzadeh, Richard N. Pierson, Benson Morrill, Amy Dandro, Kasinath Kuravi, David Ayares, Lori Sorrells, Willard Eyestone, Carol Phelps
Publikováno v:
Xenotransplantation
The transplantation of organs across species offers the potential to solve the shortage of human organs. While activation of human platelets by human von Willebrand factor (vWF) requires vWF activation by shear stress, contact between human platelets
Autor:
Hugh Auchincloss, Margaret R. Connolly
Publikováno v:
Thorac Surg Clin
The thoracic outlet is the space between the thorax and axilla through which the subclavian vein, subclavian artery, and brachial plexus travel from their central origins to their peripheral termini. Its bounds include the clavicle, first thoracic ri
Autor:
Richard N. Pierson, Zahra Alikhassy Habibabady, David Ayares, Kaitlyn Petitpas, Agnes Azimzadeh, C. Phelps, Selin Sendil, Lars Burdorf, Kasinath Kuravi, Margaret R. Connolly
Publikováno v:
The Journal of Heart and Lung Transplantation. 40:S146-S147
Purpose In normal hemostasis, activated von Willebrand factor (vWF) stimulates platelet adhesion and aggregation, but porcine vWF (pvWF) is “always active” when exposed to human blood. We hypothesized that humanized vWF (h*pvWF) would reduce this
Autor:
Richard N. Pierson, Margaret R. Connolly, Will Eyestone, Kaitlyn Petitpas, Carol Phelps, David Ayares, Agnes Azimzadeh, Xiangfei Cheng, Christopher Laird, Shannon Pratts, Benjamin Cerel, Zahra Abady, Lars Burdorf
Publikováno v:
Transplantation. 104:S637-S638