Quality control in the endoplasmic reticulum

Autor: Margaret R. Batten, Neil J. Bulleid, Richard A. Lumb, M J Bottomley

Publikováno v: Current Biology. 11(14):1114-1118

Quality control within the endoplasmic reticulum (ER) is thought to be mediated by the interaction of a folding protein with one or several resident ER proteins [1]. Protein disulphide isomerase (PDI) is one such ER resident protein that has been pre

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b9ebfd90d249d35455d703cec1800eb

Amino acid sequence requirements in the hinge of human immunoglobulin A1 (IgA1) for cleavage by streptococcal IgA1 proteases

Autor: Bernard W. Senior, Margaret R. Batten, Mogens Kilian, Jenny M. Woof

Publikováno v: Batten, MR, Senior, BW, Kilian, M & Woof, JM 2003, ' Amino acid sequence requirements in the hinge of human immunoglobulin A1 (IgA1) for cleavage by streptococcal IgA1 proteases ', Infection and Immunity, vol. 71, pp. 1462-69 .

The amino acid sequence requirements in the hinge of human immunoglobulin A1 (IgA1) for cleavage by IgA1 proteases of different species ofStreptococcuswere investigated. Recombinant IgA1 antibodies were generated with point mutations at proline 227 a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::10562fffe82d8f0277592b2130240ea5
https://pure.au.dk/portal/da/publications/amino-acid-sequence-requirements-in-the-hinge-of-human-immunoglobulin-a1-iga1-for-cleavage-by-streptococcal-iga1-proteases(febdc700-dd82-11dd-9b3b-000ea68e967b).html

Cleavage of a recombinant human immunoglobulin A2 (IgA2)-IgA1 hybrid antibody by certain bacterial IgA1 proteases

Autor: Jenny M. Woof, Bernard W. Senior, Mogens Kilian, James I. Dunlop, Margaret R. Batten

Publikováno v: Senior, B, Dunlop, JI, Batten, MR, Kilian, M & Woof, JM 2000, ' Cleavage of a recombinant human immunoglobulin A2 (IgA2)-IgA1 hybrid antibody by certain bacterial IgA1 proteases ', Infection and Immunity, vol. 68, pp. 463-69 .

To understand more about the factors influencing the cleavage of immunoglobulin A1 (IgA1) by microbial IgA1 proteases, a recombinant human IgA2/IgA1 hybrid molecule was generated. In the hybrid, termed IgA2/A1 half hinge, a seven-amino-acid sequence

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::865beb092c402ead71ae0d74b22fe560
https://pure.au.dk/portal/da/publications/cleavage-of-a-recombinant-human-immunoglobulin-a2-iga2iga1-hybrid-antibody-by-certain-bacterial-iga1-proteases(1f09f700-ff56-11dd-a987-000ea68e967b).html

Structural requirements for the interaction of human IgA with the human polymeric Ig receptor

Autor: Margaret R. Batten, Julie D. Atkin, Melanie J. Lewis, Jenny M. Woof, Richard J. Pleass

Publikováno v: Macquarie University

Transport of polymeric IgA onto mucosal surfaces to become secretory IgA is mediated by the polymeric Ig receptor (pIgR). To study the interaction of human dimeric IgA (dIgA) (the predominant form of IgA polymer) with the human pIgR (hpIgR), we gener

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c5597d45fe9fbf1d6a7623075177eff
https://researchers.mq.edu.au/en/publications/542c2a58-d6d7-401d-8541-23f32d864066