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pro vyhledávání: '"Margaret R Little"'
Autor:
Tao Han, Shulong Jiang, Hong Zheng, Qing Yin, Mengyu Xie, Margaret R Little, Xiu Yin, Ming Chen, Su Jung Song, Amer A. Beg, Pier Paolo Pandolfi, Lixin Wan
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-15 (2019)
The Anaphase Promoting Complex adaptor protein Cdh1 tightly controls cell cycle progression to restrain tumorigenesis but the mechanism is not completely known. Here, the authors show that reciprocal inhibition between Cdh1 and the c-Src signaling pa
Externí odkaz:
https://doaj.org/article/0384f8d299bb452ab948ffee2b150f84
Autor:
Amer A. Beg, Pier Paolo Pandolfi, Lixin Wan, Hong Zheng, Su Jung Song, Xiu Yin, Tao Han, Mengyu Xie, Qing Yin, Ming Chen, Shulong Jiang, Margaret R Little
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-15 (2019)
Nature Communications
Nature Communications
The Anaphase Promoting Complex (APC) coactivator Cdh1 drives proper cell cycle progression and is implicated in the suppression of tumorigenesis. However, it remains elusive how Cdh1 restrains cancer progression and how tumor cells escape the inhibit