Zobrazeno 1 - 10
of 60
pro vyhledávání: '"Margaret P. Price"'
Autor:
Lynda S Ostedgaard, Margaret P Price, Kristin M Whitworth, Mahmoud H Abou Alaiwa, Anthony J Fischer, Akshaya Warrier, Melissa Samuel, Lee D Spate, Patrick D Allen, Brieanna M Hilkin, Guillermo S Romano Ibarra, Miguel E Ortiz Bezara, Brian J Goodell, Steven E Mather, Linda S Powers, Mallory R Stroik, Nicholas D Gansemer, Camilla E Hippee, Keyan Zarei, J Adam Goeken, Thomas R Businga, Eric A Hoffman, David K Meyerholz, Randall S Prather, David A Stoltz, Michael J Welsh
Publikováno v:
eLife, Vol 9 (2020)
Submucosal glands (SMGs) are a prominent structure that lines human cartilaginous airways. Although it has been assumed that SMGs contribute to respiratory defense, that hypothesis has gone without a direct test. Therefore, we studied pigs, which hav
Externí odkaz:
https://doaj.org/article/de4e52b4b350483bb95240e3006ac61e
Autor:
Jianyang Du, Margaret P Price, Rebecca J Taugher, Daniel Grigsby, Jamison J Ash, Austin C Stark, Md Zubayer Hossain Saad, Kritika Singh, Juthika Mandal, John A Wemmie, Michael J Welsh
Publikováno v:
eLife, Vol 6 (2017)
Attenuating the strength of fearful memories could benefit people disabled by memories of past trauma. Pavlovian conditioning experiments indicate that a retrieval cue can return a conditioned aversive memory to a labile state. However, means to enha
Externí odkaz:
https://doaj.org/article/6b2d242ced6e4180844251c8e8059ae2
Autor:
Leah R Reznikov, David K Meyerholz, Ryan J Adam, Mahmoud Abou Alaiwa, Omar Jaffer, Andrew S Michalski, Linda S Powers, Margaret P Price, David A Stoltz, Michael J Welsh
Publikováno v:
PLoS ONE, Vol 11, Iss 11, p e0166089 (2016)
Neurons innervating the airways contribute to airway hyperreactivity (AHR), a hallmark feature of asthma. Several observations suggested that acid-sensing ion channels (ASICs), neuronal cation channels activated by protons, might contribute to AHR. F
Externí odkaz:
https://doaj.org/article/c513c0677be546cd938cebe2e8f18d2a
Autor:
Eric A. Hoffman, Randall S. Prather, Thomas R. Businga, Margaret P. Price, Lynda S. Ostedgaard, Guillermo S Romano Ibarra, Brian J Goodell, Patrick D Allen, Mallory R. Stroik, Melissa Samuel, Miguel E Ortiz Bezara, David K. Meyerholz, Camilla E Hippee, Steven E Mather, Linda S. Powers, Michael J. Welsh, Lee D. Spate, Nicholas D. Gansemer, Mahmoud H. Abou Alaiwa, Brieanna M Hilkin, Akshaya Warrier, Kristin M. Whitworth, David A. Stoltz, J. Adam Goeken, Anthony J. Fischer, Keyan Zarei
Publikováno v:
eLife
eLife, Vol 9 (2020)
eLife, Vol 9 (2020)
Submucosal glands (SMGs) are a prominent structure that lines human cartilaginous airways. Although it has been assumed that SMGs contribute to respiratory defense, that hypothesis has gone without a direct test. Therefore, we studied pigs, which hav
Autor:
Akshaya Warrier, Lynda S. Ostedgaard, Michael J. Welsh, Randall S. Prather, Thomas R. Businga, Margaret P. Price, Brieanna M Hilkin, Lee D. Spate, Miguel E Ortiz Bezara, Camilla E Hippee, Guillermo S Romano Ibarra, Keyan Zarei, Patrick D Allen, Steven E Mather, J. Adam Goeken, Mahmoud H. Abou Alaiwa, Linda S. Powers, Anthony J. Fischer, Kristin M. Whitworth, David A. Stoltz, Melissa Samuel, David K. Meyerholz, Mallory R. Stroik, Eric A. Hoffman, Nicholas D. Gansemer, Brian J Goodell
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a86286ac82a3812b35bfef1950a736ec
https://doi.org/10.7554/elife.59653.sa2
https://doi.org/10.7554/elife.59653.sa2
Autor:
Sinyoung Kang, Jun Ho Jang, Margaret P Price, Mamta Gautam, Christopher J Benson, Huiyu Gong, Michael J Welsh, Timothy J Brennan
Publikováno v:
PLoS ONE, Vol 7, Iss 4, p e35225 (2012)
Three observations have suggested that acid-sensing ion channels (ASICs) might be mammalian cutaneous mechanoreceptors; they are structurally related to Caenorhabditis elegans mechanoreceptors, they are localized in specialized cutaneous mechanosenso
Externí odkaz:
https://doaj.org/article/82a4bf65d75e4866a876a0cb7a2c5d48
Autor:
Thomas B. Bair, Leah R. Reznikov, Michael J. Welsh, Nicholas L. Bormann, David A. Stoltz, Shin-Ping Kuan, David K. Meyerholz, Margaret P. Price, Yan-Shin J. Liao, Mahmoud H. Abou Alaiwa
Publikováno v:
American Journal of Physiology-Lung Cellular and Molecular Physiology. 315:L133-L148
Mainstay therapeutics are ineffective in some people with asthma, suggesting a need for additional agents. In the current study, we used vagal ganglia transcriptome profiling and connectivity mapping to identify compounds beneficial for alleviating a
Autor:
John A. Wemmie, Rebecca J. Taugher, Jamison J Ash, Daniel Grigsby, Michael J. Welsh, Zubayer Hossain Saad, Kritika Singh, Austin C Stark, Jianyang Du, Juthika Mandal, Margaret P. Price
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8fea64f4fcf36a9df23372e3c373e625
https://doi.org/10.7554/elife.22564.018
https://doi.org/10.7554/elife.22564.018
Autor:
Juthika Mandal, John A. Wemmie, Jamison J Ash, Austin C Stark, Jianyang Du, Daniel Grigsby, Zubayer Hossain Saad, Kritika Singh, Margaret P. Price, Rebecca J. Taugher, Michael J. Welsh
Publikováno v:
eLife
eLife, Vol 6 (2017)
eLife, Vol 6 (2017)
Attenuating the strength of fearful memories could benefit people disabled by memories of past trauma. Pavlovian conditioning experiments indicate that a retrieval cue can return a conditioned aversive memory to a labile state. However, means to enha
Autor:
John A. Wemmie, George B. Richerson, Huiyu Gong, Jacob R. Kundert, Luisa Bernardinelli, Meredith G. Parsons, Margaret P. Price, Gordon F. Buchanan, Michael J. Welsh, Leah R. Reznikov, Martin D. Cassell, Kathryn Chaloner
Publikováno v:
Genes, Brain and Behavior. 13:179-194
Acid-sensing ion channels (ASICs) generate H(+) -gated Na(+) currents that contribute to neuronal function and animal behavior. Like ASIC1, ASIC2 subunits are expressed in the brain and multimerize with ASIC1 to influence acid-evoked currents and fac