Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Margaret Mentink-Kane"'
Autor:
Neil D. Young, Andreas J. Stroehlein, Tao Wang, Pasi K. Korhonen, Margaret Mentink-Kane, J. Russell Stothard, David Rollinson, Robin B. Gasser
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-15 (2022)
The snail Bulinus truncatus is an intermediate host of the carcinogenic human blood fluke Schistosoma haematobium. Here the authors report the genome of Bu. truncatus, explore protein groups inferred to play a role in its interaction with the schisto
Externí odkaz:
https://doaj.org/article/8cd0b85e29f14f97b9f78b107fb38b5c
Autor:
Biruk Kassa, Michael H Lee, Rahul Kumar, Claudia Mickael, Linda Sanders, Rubin M Tuder, Margaret Mentink-Kane, Brian B Graham
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 16, Iss 4, p e0010343 (2022)
BackgroundSchistosomiasis, a major cause of pulmonary arterial hypertension (PAH) worldwide, is most clearly described complicating infection by one species, Schistosoma mansoni. Controlled exposure of mice can be used to induce Type 2 inflammation-d
Externí odkaz:
https://doaj.org/article/598c70bd548d40a9ac150d51cce361c6
Autor:
Andreas J. Stroehlein, Pasi K. Korhonen, V. Vern Lee, Stuart A. Ralph, Margaret Mentink-Kane, Hong You, Donald P. McManus, Louis-Albert Tchuem Tchuenté, J. Russell Stothard, Parwinder Kaur, Olga Dudchenko, Erez Lieberman Aiden, Bicheng Yang, Huanming Yang, Aidan M. Emery, Bonnie L. Webster, Paul J. Brindley, David Rollinson, Bill C. H. Chang, Robin B. Gasser, Neil D. Young
Publikováno v:
PLoS Pathogens, Vol 18, Iss 2 (2022)
Urogenital schistosomiasis is caused by the blood fluke Schistosoma haematobium and is one of the most neglected tropical diseases worldwide, afflicting > 100 million people. It is characterised by granulomata, fibrosis and calcification in urogenita
Externí odkaz:
https://doaj.org/article/fefe19173810481c8b859d7a47f4f70f
Publikováno v:
Frontiers in Microbiology, Vol 12 (2021)
On entering the mammalian host, schistosomes transition from a freshwater environment where resources are scarce, to an environment where there is an unlimited supply of glucose, their preferred energy substrate. Adult schistosome glycolytic activity
Externí odkaz:
https://doaj.org/article/1c091edc18c142a9b62a9844bfad2163
Autor:
Karlie Jones, Angela Ballesteros, Margaret Mentink-Kane, James Warren, Shemona Rattila, Harry Malech, Elizabeth Kang, Gabriela Dveksler
Publikováno v:
PLoS ONE, Vol 11, Iss 7, p e0158050 (2016)
The pregnancy-specific glycoproteins (PSGs) are a family of proteins secreted by the syncytiotrophoblast of the placenta and are the most abundant trophoblastic proteins in maternal blood during the third trimester. The human PSG family consists of 1
Externí odkaz:
https://doaj.org/article/d6de079d1f2447da9cad73dbd11c5fe9
Autor:
Wannaporn Ittiprasert, Max F. Moescheid, Cristian Chaparro, Victoria H. Mann, Thomas Quack, Rutchanee Rodpai, André Miller, Prapakorn Wistiphongpun, Watunyoo Buakaew, Margaret Mentink-Kane, Sarah Schmid, Anastas Popratiloff, Christoph G. Grevelding, Christoph Grunau, Paul J. Brindley
SummaryThe identification and characterization of genomic safe harbor sites (GSH) aims to facilitate consistent transgene activity without disruption to the host cell genome. We combined genome annotation and chromatin structure analysis by computati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::faa1cc26463e7e3a2df011a69975b0e3
https://doi.org/10.1101/2022.09.02.506379
https://doi.org/10.1101/2022.09.02.506379
Autor:
Wannaporn, Ittiprasert, Chawalit, Chatupheeraphat, Victoria H, Mann, Wenhui, Li, André, Miller, Taiwo, Ogunbayo, Kenny, Tran, Yousef N, Alrefaei, Margaret, Mentink-Kane, Paul J, Brindley
Publikováno v:
International Journal of Molecular Sciences
The efficiency of the RNA-guided AsCas12a nuclease of Acidaminococcus sp. was compared with SpCas9 from Streptococcus pyogenes, for functional genomics in Schistosoma mansoni. We deployed optimized conditions for the ratio of guide RNAs to the nuclea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f773bf3e15f8633769ef4e6d544d478d
https://pubmed.ncbi.nlm.nih.gov/35054816
https://pubmed.ncbi.nlm.nih.gov/35054816
Autor:
Andreas J. Stroehlein, Pasi K. Korhonen, V. Vern Lee, Stuart A. Ralph, Margaret Mentink-Kane, Hong You, Donald P. McManus, Louis-Albert Tchuem Tchuenté, J. Russell Stothard, Parwinder Kaur, Olga Dudchenko, Erez Lieberman Aiden, Bicheng Yang, Huanming Yang, Aidan M. Emery, Bonnie L. Webster, Paul J. Brindley, David Rollinson, Bill C. H. Chang, Robin B. Gasser, Neil D. Young
Publikováno v:
PLoS Pathogens, Vol 18, Iss 2 (2022)
Urogenital schistosomiasis is caused by the blood fluke Schistosoma haematobium and is one of the most neglected tropical diseases worldwide, afflicting > 100 million people. It is characterised by granulomata, fibrosis and calcification in urogenita
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::691fcef8303d1df682b703bffa336949
https://pubmed.ncbi.nlm.nih.gov/35167626
https://pubmed.ncbi.nlm.nih.gov/35167626
Autor:
Biruk Kassa, Michael H. Lee, Rahul Kumar, Claudia Mickael, Linda Sanders, Rubin M. Tuder, Margaret Mentink-Kane, Brian B. Graham
Publikováno v:
PLoS neglected tropical diseases, vol 16, iss 4
BackgroundSchistosomiasis, a major cause of pulmonary arterial hypertension (PAH) worldwide, is most clearly described complicating infection by one species,Schistosoma mansoni. Controlled exposure of mice can be used to induce Type 2 inflammation-de
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb7fbe7af477ecf5660a020faaaad2d8
https://pubmed.ncbi.nlm.nih.gov/35417453
https://pubmed.ncbi.nlm.nih.gov/35417453
Autor:
Neil D, Young, Andreas J, Stroehlein, Tao, Wang, Pasi K, Korhonen, Margaret, Mentink-Kane, J Russell, Stothard, David, Rollinson, Robin B, Gasser
Publikováno v:
Nature communications. 13(1)
Some snails act as intermediate hosts (vectors) for parasitic flatworms (flukes) that cause neglected tropical diseases, such as schistosomiases. Schistosoma haematobium is a blood fluke that causes urogenital schistosomiasis and induces bladder canc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::80e2d2b5c530a4e1c0e0d7668c02b215
https://pubmed.ncbi.nlm.nih.gov/35190553
https://pubmed.ncbi.nlm.nih.gov/35190553