Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Margaret MacMorris"'
Publikováno v:
Proceedings of the National Academy of Sciences. 105:16665-16670
RNA polymerase II (Pol II) transcription termination involves two linked processes: mRNA 3′-end formation and release of Pol II from DNA. Signals for 3′ processing are recognized by a protein complex that includes cleavage polyadenylation specifi
Publikováno v:
Proceedings of the National Academy of Sciences. 104:9753-9757
In Caenorhabditis elegans , the small nuclear ribonucleoprotein (snRNP)-associated proteins U1A and U2B″ are ≈50% identical to each other, and neither bears signature characteristics of mammalian U1A or U2B″ or the single Drosophila homolog, SN
Autor:
John F. Hutton, Erin Domke, Tobias R. Zahn, Margaret MacMorris, Cindi L. Schwartz, Joseph K. Angleson, John C. Hutton
Publikováno v:
Traffic. 5:544-559
We have developed a model system in Caenorhabditis elegans to perform genetic and molecular analysis of peptidergic neurotransmission using green fluorescent protein (GFP)-tagged IDA-1. IDA-1 represents the nematode ortholog of the transmembrane prot
Publikováno v:
RNA. 9:847-857
Expression of a gfp transgene in the intestines of living Caenorhabditis elegans has been measured following depletion by RNAi of a variety of known splicing factors and mRNA export proteins. Reduction of most splicing factors showed only a small eff
Autor:
Thomas Blumenthal, Donald Evans, Devin Leake, Carol J. Wilusz, Margaret MacMorris, Ismael Perez
Publikováno v:
Genes & Development. 15:2562-2571
Between 15% and 25% of Caenorhabditis elegans genes are organized in polycistronic transcription units, or operons (Zorio et al. 1994; T. Blumenthal, D. Evans, C. Link, A. Guffanti, D. Lawson, J. Thierry-Mieg, D. Thierry-Mieg, K. Duke, and S. Kim, in
Publikováno v:
RNA. 7:176-181
About half of Caenorhabditis elegans genes have a 1-2 bp mismatch to the canonical AAUAAA hexamer that signals 3' end formation. One rare variant, AGUAAA, is found at the 3' end of the mai-1 gene, the first gene in an operon also containing gpd-2 and
Publikováno v:
The Journal of Comparative Neurology. 429:127-143
The closely related mammalian proteins IA-2 and phogrin are protein tyrosine phosphatase-like receptor proteins spanning the membrane of dense core vesicles of neuroendocrine tissues. They are of interest as molecular components of the secretory mach
Publikováno v:
Molecular and Cellular Biology. 14:484-491
The Caenorhabditis elegans vit genes, encoding vitellogenins, are abundantly expressed in the adult hermaphrodite intestine. Two repeated elements, vit promoter element 1 (VPE1 [TGTCAAT]) and VPE2 (CTGATAA), have been identified in the 5' flanking DN
Publikováno v:
Developmental biology. 84(2)
A temperature-sensitive mutant strain (shibire) has been used to probe the normal developmental process in Drosophila melanogaster. At high temperatures lethality occurs during embryonic development. Heat pulses given early disrupt cellular blastoder
Autor:
Margaret MacMorris, Alison Larsen, Thomas Blumenthal, Madhur Kumar, Brian C. Kraemer, Erika Lasda
Publikováno v:
RNA (New York, N.Y.). 13(4)
In many Caenorhabditis elegans pre-mRNAs, the RNA sequence between the 5′ cap and the first 3′ splice site is replaced by trans-splicing a short spliced leader (SL) from the Sm snRNP, SL1. C. elegans also utilizes a similar Sm snRNP, SL2, to tran