Zobrazeno 1 - 10
of 43
pro vyhledávání: '"Margaret M. Shaw"'
Publikováno v:
Biotechnology Progress. 34:570-583
Mammalian cell line development is critical to bioproduct manufacturing. Success requires selecting a line with desirable performance characteristics, including consistent expression throughout the proposed manufacturing window. Given the genetic and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::015109df4bf2841eacc00861201748d7
https://doi.org/10.1002/btpr.2667
https://doi.org/10.1002/btpr.2667
Publikováno v:
Biotechnology progress. 34(3)
Mammalian cell line development is critical to bioproduct manufacturing. Success requires selecting a line with desirable performance characteristics, including consistent expression throughout the proposed manufacturing window. Given the genetic and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::6846cee38220002e49808e1c5d80a090
https://pubmed.ncbi.nlm.nih.gov/29882242
https://pubmed.ncbi.nlm.nih.gov/29882242
Autor:
Margaret M. Shaw, Cullen H. Blake
Publikováno v:
Publications of the Astronomical Society of the Pacific. 123:1302-1312
Modeling molecular absorption by Earth's atmosphere is important for a wide range of astronomical observations, including broadband NIR photometry and high-resolution NIR spectroscopy. Using a line-by-line radiative transfer approach, we calculate th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b77d0d9546bb54bd0eaa709f1f852b93
https://doi.org/10.1086/662980
https://doi.org/10.1086/662980
Publikováno v:
Antimicrobial Agents and Chemotherapy. 45:1473-1479
Atovaquone is a chemotherapeutic agent used to treat pneumonia caused by Pneumocystis carinii in some immunocompromised patients. A set of cyclic 1,4-diones were tested in vitro for ability to inhibit growth of P. carinii , including 22 variously sub
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4cd3adab1d4b941804a586d000e47b47
https://doi.org/10.1128/aac.45.5.1473-1479.2001
https://doi.org/10.1128/aac.45.5.1473-1479.2001
Autor:
Pamela J. Durant, Chao-Hung Lee, Marilyn S. Bartlett, William C. Angus, Margaret M. Shaw, James W. Smith, Juan M. Pascale
Publikováno v:
Clinical Diagnostic Laboratory Immunology. 5:74-77
Well-proven mouse and rat models were used to show that polyclonal antisera to Pneumocystis carinii protect against P. carinii pneumonia. Antibodies were obtained from animals that were allowed to recover from severe P. carinii pneumonia after immuno
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::002c8bf19f87e7ecfea6a6aa6055890e
https://doi.org/10.1128/cdli.5.1.74-77.1998
https://doi.org/10.1128/cdli.5.1.74-77.1998
Autor:
Henry Koziel, Marilyn S. Bartlett, Margaret M. Shaw, Gerald L. McLaughlin, Stephen T. Furlong, R M Jack
Publikováno v:
Journal of Infectious Diseases. 175:661-668
Pneumocystis carinii lipids are similar to host lipids, but it is not known if some of these lipids are acquired from host cells. The ability of P. carinii to incorporate a fluorescent fatty acid analogue (Bodipy-C12) was analyzed, the metabolism of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07541e8c77d18dc79b1beaea7f1d0a4e
https://doi.org/10.1093/infdis/175.3.661
https://doi.org/10.1093/infdis/175.3.661
Semisynthetic echinocandins affect cell wall deposition of Pneumocystis carinii in vitro and in vivo
Autor:
Carole J. Boylan, Michael P. Goheen, W. L. Current, James W. Smith, Sherry F. Queener, Margaret M. Shaw, Chao-Hung Lee, Marilyn S. Bartlett
Publikováno v:
Antimicrobial Agents and Chemotherapy. 40:1811-1816
Cyclic lipodepsipeptide compounds of the echinocandin class exhibit broad-spectrum antifungal activity and have been shown to be effective in the treatment of Pneumocystis carinii pneumonia in laboratory animal models. Previous studies have led inves
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::60a72af204233862b7e663492a2a9a2b
https://doi.org/10.1128/aac.40.8.1811
https://doi.org/10.1128/aac.40.8.1811
Autor:
J. W. Smith, R. Dean, Marilyn S. Bartlett, Margaret M. Shaw, Chao-Hung Lee, Sherry F. Queener, T. D. Edlind
Publikováno v:
Antimicrobial Agents and Chemotherapy. 38:1834-1837
Albendazole, a benzimidazole derivative widely used for treating helminth infections, was successfully used to treat and prevent development of Pneumocystis carinii pneumonia in transtracheally inoculated immunosuppressed mice. For treatment, 3 weeks
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ab759d149e3507c2cb1ec7dba60c4c6
https://doi.org/10.1128/aac.38.8.1834
https://doi.org/10.1128/aac.38.8.1834
Autor:
Michelle Durkin, James W. Smith, Chao-Hung Lee, Michael P. Goheen, Margaret M. Shaw, Marilyn S. Bartlett
Publikováno v:
Parasitology Research. 80:208-215
Studies of the association of rat-origin Pneumocystis carinii with culture cells were performed both to learn more about the role of cells in P. carinii culture and to evaluate additional cell lines in an effort to improve culture methods. Proliferat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::21affb5812f49086e53182a6b506a59f
https://doi.org/10.1007/bf00932676
https://doi.org/10.1007/bf00932676
Autor:
Ibrahim Kadura, Lianchun Fan, Lara E. Krebs, Christopher C. Hatfield, Christopher C. Frye, Margaret M. Shaw
Publikováno v:
Biotechnology and bioengineering. 109(4)
Although Chinese hamster ovary (CHO) cells, with their unique characteristics, have become a major workhorse for the manufacture of therapeutic recombinant proteins, one of the major challenges in CHO cell line generation (CLG) is how to efficiently
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ddec35d993ec36ada3da1db705a61b49
https://pubmed.ncbi.nlm.nih.gov/22068567
https://pubmed.ncbi.nlm.nih.gov/22068567