Zobrazeno 1 - 10
of 97
pro vyhledávání: '"Margaret M. Kayser"'
Publikováno v:
ARKIVOC, Vol 2002, Iss 12, Pp 47-62 (2003)
Externí odkaz:
https://doaj.org/article/2d8dfee9186b42c3813a56c6a496b16a
Autor:
Margaret M. Kayser
Publikováno v:
Tetrahedron. 65:947-974
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f69febbd679b87a142e19e9a87980aca
https://doi.org/10.1016/j.tet.2008.10.039
https://doi.org/10.1016/j.tet.2008.10.039
Publikováno v:
Microporous and Mesoporous Materials. 116:196-203
Enantiopure sulfoxides prepared via biooxidation with engineered yeast (Saccharomyces cerevisiae) and E. coli overexpressing enzyme cyclohexanone monooxygenase (CHMO) were used as chiral liners for mesoporous silica SBA-15. The protocols for attachme
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7bb1a049455366ff6e952e0f2f9f6933
https://doi.org/10.1016/j.micromeso.2008.04.002
https://doi.org/10.1016/j.micromeso.2008.04.002
Publikováno v:
Tetrahedron: Asymmetry. 18:2021-2029
We report a synthesis of pharmaceutically important α-hydroxy (or t -butyldimethylsilyl protected α-hydroxy)-β-lactams with functionalized chains in position 4 of the azetidinone ring. A convenient and high-yielding route to these compounds was de
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c5e02f642aca92e89979235bd07133c4
https://doi.org/10.1016/j.tetasy.2007.08.012
https://doi.org/10.1016/j.tetasy.2007.08.012
Publikováno v:
Journal of Molecular Catalysis B: Enzymatic. 46:32-36
The Escherichia coli (E. coli) overexpression systems of Baeyer–Villiger monooxygenases (BVMOs), cyclohexanone monooxygenase (CHMO) and cyclopentanone monooxygenase (CPMO) and their mutants derived from directed evolution were used as catalysts in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2f88e94baa2db443776ef814c3181a8c
https://doi.org/10.1016/j.molcatb.2007.02.001
https://doi.org/10.1016/j.molcatb.2007.02.001
Publikováno v:
The Journal of Organic Chemistry. 72:756-759
The kinetic resolution of racemic cis-4-phenyl- and cis-4-tert-butyl-3-hydroxy-beta-lactam derivatives with 7-O-triethylsilylbaccatin III yielded paclitaxel and butitaxel analogues with high diastereoselectivity. The results demonstrated that the ter
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e083de8384490601029b76e76ffdc41
https://doi.org/10.1021/jo061339s
https://doi.org/10.1021/jo061339s
Publikováno v:
Tetrahedron: Asymmetry. 17:2649-2653
A series of cyclohexanones substituted at the 4-position with a selection of hydrophobic and hydrophilic groups were used as substrates in the evaluation of six new cyclopentanone monooxygenase (CPMO) mutants. These mutants were obtained through evol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::739a5c5168fe3aa41a9f1bb140cf67fb
https://doi.org/10.1016/j.tetasy.2006.10.001
https://doi.org/10.1016/j.tetasy.2006.10.001
Publikováno v:
Tetrahedron: Asymmetry. 16:4004-4009
Homochiral 3-hydroxy-4-substituted β-lactams serve as precursors to the corresponding α-hydroxy-β-amino acids—key components of many biologically and therapeutically important compounds. We have developed a short synthetic sequence for these tar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::19bf3ad1c47cdc43414f78834a534dba
https://doi.org/10.1016/j.tetasy.2005.11.008
https://doi.org/10.1016/j.tetasy.2005.11.008
Publikováno v:
Tetrahedron: Asymmetry. 16:2748-2753
Using a recombinant E. coli strain overexpressing yeast reductase Ara1p, we reduced racemic 3-oxo-4-phenyl-β-lactam to cis -(3 S ,4 R )-3-hydroxy-4-phenyl-β-lactam as a single enantiopure product. The dynamic kinetic resolution occurred over the co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d91ebc932fa9adda01bb4db3535dae13
https://doi.org/10.1016/j.tetasy.2005.07.029
https://doi.org/10.1016/j.tetasy.2005.07.029
Publikováno v:
Chirality. 17:131-134
The absolute configurations of several 3-hydroxy β-lactams were assigned by the NMR “mix and shake” methodology developed by Riguera and co-workers. The results from the NMR study correlated perfectly with the absolute configurations obtained fr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::137fbb04c25f1a6220f40d83e1fffc25
https://doi.org/10.1002/chir.20125
https://doi.org/10.1002/chir.20125