Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Margaret M. Halloran"'
Autor:
Michael V. Volin, Margaret M. Halloran, Alisa E. Koch, Steven L. Kunkel, James M. Woods, Robert M. Strieter, Zoltán Szekanecz, G. Kenneth Haines, Marie D. Burdick
Publikováno v:
Arthritis & Rheumatism. 43:1266-1277
OBJECTIVE To examine cytokine and chemokine production during the evolution of rat adjuvant-induced arthritis (AIA), a model of rheumatoid arthritis. METHODS Clinical and laboratory assessment of the course of AIA was performed over a 47-day period.
Autor:
Margaret M. Halloran, James M. Woods, Robert M. Strieter, Zoltan Szekanecz, Michael V. Volin, Shigeru Hosaka, G. Kenneth Haines, Steven L. Kunkel, Marie D. Burdick, Alfred Walz, Alisa E. Koch
Publikováno v:
The Journal of Immunology. 162:7492-7500
The chemokine, epithelial neutrophil-activating peptide-78 (ENA-78), is a potent neutrophil chemotaxin whose expression is increased in inflamed synovial tissue and fluid in human rheumatoid arthritis compared with osteoarthritis. Since ENA-78 has be
Autor:
Manisha R. Shah, Alisa E. Koch, Catherine J. Haskell, Zoltán Szekanecz, Margaret M. Halloran, Peter J. Polverini
Publikováno v:
Trends in Glycoscience and Glycotechnology. 11:73-93
新しい血管を作り出す血管造成は発生、組織修復、炎症、動脈硬化症や腫瘍の進展など数多くの生理的、病理的過程で重要な役割を果たしている。サイトカイン、成長因子、その他の多
Publikováno v:
Pathobiology. 65:287-292
Interleukin-13 (IL-13) is a recently described lymphokine. Like IL-4, IL-13 induces the production of IL-1 receptor antagonists and suppresses the production of inflammatory cytokines by macrophages and monocytes. In this study, we investigated the e
Autor:
Manisha R. Shah, Steven K. Baker, Richard M. Pope, Catherine J. Haskell, Ralph J. Panos, Shigeru Hosaka, Margaret M. Halloran, Gregory L. Bennett, G. Kenneth Haines, Alisa E. Koch, Napoleone Ferrara
Publikováno v:
Arthritis & Rheumatism. 39:1566-1575
Objective. Angiogenesis is an integral component of the vasculoproliferative phase of rheumatoid arthritis (RA). Recently, a heparin-binding cytokine termed hepatocyte growth factor (HGF), or scatter factor (due to its ability to disperse cohesive ep
Publikováno v:
Arthritis & Rheumatism. 39:810-819
Objective. To examine adhesion molecule expression during the progression of inflammation in a rheumatoid arthritis model of adjuvant-induced arthritis (AIA) in rats. Methods. Immunohistochemical analysis was used to determine the distribution of the
Autor:
James M. Woods, Michael V. Volin, Margaret M. Halloran, Stacie Phan, Phillip L. Campbell, William Carley, Catherine J. Haskell, Byron J. Anderson, Alisa E. Koch, Annika E. Bäcker, Peter J. Polverini
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 164(9)
Endothelial cells (ECs) are key participants in angiogenic processes that characterize tumor growth, wound repair, and inflammatory diseases, such as human rheumatoid arthritis (RA). We and others have shown that EC molecules, such as soluble E-selec
Autor:
Jessenia Magua, Alisa E. Koch, James M. Woods, Zoltán Szekanecz, John A. Damergis, Michael V. Volin, Margaret M. Halloran, Paul R. Crocker, Kenneth Haines
Publikováno v:
Experimental and molecular pathology. 66(3)
A hallmark of both adjuvant-induced arthritis (AIA) and rheumatoid arthritis is chronic joint inflammation characterized by ingress of leukocytes into the inflamed synovial tissue. The timing of expression of adhesion molecules, which govern the ingr
Autor:
Anthony N. Karnezis, Richard G. Pestell, Richard T. Lee, Genichi Watanabe, Alisa E. Koch, G K Haines, Frank Erfurth, Betty Ann Brody, Margaret M. Halloran, George E. Shambaugh
Publikováno v:
Journal of neuropathology and experimental neurology. 55(9)
Nutritional deprivation in the early postnatal period severely inhibits cerebellar growth and development, which is related in part to reduced levels of growth factors. Cyclin D1 encodes a growth factor-inducible regulatory subunit of a serine/threon
Autor:
Michael V. Volin, Alisa E. Koch, Margaret M. Halloran, G K Haines, James M. Woods, Zoltán Szekanecz
Publikováno v:
Arthritis Research
Adjuvant-induced arthritis (AIA) in rats is a relevant model for human rheumatoid arthritis (RA). In this study, th expression of the cytokines TNF-alpha, IL-1 and IL-6, as well as the chemokines MIP-1-alpha, MCP-1 and ENA-78 in the sera and joint ho